Results 141 to 150 of about 50,219 (296)

The nanosyntax of French negation : a diachronic perspective

, 2016
This paper presents a nanosyntactic account for negation in what is referred to as le bon usage French (Grevisse and Goosse [1936] 1993, Rooryck 2010) and in colloquial French.
Cruscina, Silvioeditor, Remberger, Eva-Mariaeditor, De Clercq, KarenUGent0019990924978020006520579717346170480000-0003-4235-76331C3B70A2-F0EE-11E1-A9DE-61C894A0A6B4, Hartmann, Katharinaeditor   +3 more
core  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Health promotion as an opportunity for emancipation - DOI: 10.3395/reciis.v1i2.88en

RECIIS, 2007
In the present work the possibilities offered by health promotion, reviewed as a negation of negation and its identity, in contrast with the presently understood model of health/disease, circular and reproductive in nature, are discussed.
Fernando Lefevre, Ana Maria Cavalcanti Lefevre   +1 more
doaj  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

The difficulties faced by the sixth semester students of English and Literature Department in learning negation in english at Adab and Humanities Faculty of Makassar Alauddin State Islamic University (academic year 2012-2013)

, 2014
The study found that 41,62 as mean score of negation test. It was classified as 'very poor' belongs to 0-50 and students' difficulties to learn negation was 'neutral' which means score was 65,82 included 60-79. These findings were supported by students's
Salasinnai
core  

A negação sintática em diálogos do alemão e do português do Brasil

Pandaemonium Germanicum: Revista de Estudos Germanísticos, 2001
Der Aufsatz präsentiert die Ergebnisse einer Untersuchung der syntaktischen Negation in deutschen und brasilianischen Dialogen. Nach einigen Überlegungen über Negation und Sprache wird ihre Okkurrenz in einem Corpus von Dialogen in beiden Sprachen in ...
Selma M. Meireles
doaj