Results 131 to 140 of about 36,760 (309)

Generalisation of Patriarchy in Pakistan: Analysing Negation Concerning Women in Ziauddin Yousafzai’s Let Her Fly

Journal of Contemporary Poetics
Negation is a linguistic tool used to express denial, contradiction, non-existence, or falsification of a proposition or a sentence. This paper highlights the use of negation as a strategy to misrepresent Pakistani society as highly patriarchal ...
Maria Noureen, Iqra Maab, Irum Musa
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Evoking the Possibility of Presence:Textual and Ideological Effects of Linguistic Negation in Written Discourse

This thesis explores the textual and ideological effects of linguistic negation in written texts. It argues that when language users process negation, understanding its use in context is as much about the possibility of presence as it is about the ...
Nahajec, Lisa Margaret
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Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Playground of gender : cross-dressing and self-mutilation as negation of gender identity in Tanja Duckers’s Spielzone (1999) [PDF]

, 2014
Although it is an outstanding example of writing life as negotiation of gender roles as well as exploration of the body as site of identity constructs, Tanja Dückers’s novel Spielzone, published in 1999, has not yet received the critical attention it ...
Dautel, Katrin
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Sentence negation in the local dialects of the Čabar area,

Hrvatski Dijalektološki Zbornik
Syntactic negation is divided into sentence negation and partial negation. Sentence negation through a negated predicate negates the sentence content completely, while partial negation negates the content of a non-predicate member of the sentence ...
Iva Nazalević Čučević, Marija Malnar Jurišić   +1 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Silence as negation. The strategy and beyond

, 2017
Silence is neither separate from nor the opposite of communication. The inclusion of silence on a par with speech and non-verbal means is a vital element of any communication strategy. The more indirect communication is, the more silent it becomes at any
Dimitrov, RG ; https://orcid.org/
core  

Negative fragment answers [PDF]

, 2020
This chapter discusses the interaction of negation with fragment answers. The ability to use negative concorditems as fragment answers has been taken as evidence their having aninherent negative force; this chapter considers positions for and against ...
Weir, Andrew
core