Results 91 to 100 of about 13,221 (154)

On-Cell Saturation Transfer Difference NMR Spectroscopy on Ion Channels: Characterizing Negative Allosteric Modulator Binding Interactions of P2X7. [PDF]

J Am Chem Soc
Monaco S, Browne J, Wallace M, Angulo J, Stokes L.   +4 more
europepmc   +1 more source

Safety and Efficacy of the NMDA-2b-Selective Negative Allosteric Modulator BI 1569912: A Phase Ib Randomized Trial in Major Depressive Disorder. [PDF]

Clin Pharmacol Ther
McIntyre RS, Sanacora G, Walling DP, Cohen EA, Malhotra S, Rosenbrock H, Schmitz M, Scholz A, Süssmuth SD, De Crescenzo F.   +9 more
europepmc   +1 more source

Correction to: Effects of CB1 receptor negative allosteric modulator Org27569 on oxycodone withdrawal symptoms in mice. [PDF]

Psychopharmacology (Berl)
Scicluna RL, Everett NA, Badolato CJ, Wilson BB, Bowen MT.   +4 more
europepmc   +1 more source

Effects of CB1 receptor negative allosteric modulator Org27569 on oxycodone withdrawal symptoms in mice. [PDF]

Psychopharmacology (Berl)
Scicluna RL, Everett NA, Badolato CJ, Wilson BB, Bowen MT.   +4 more
europepmc   +1 more source

The mGlu5 receptor negative allosteric modulator mavoglurant reduces escalated cocaine self-administration in male and female rats. [PDF]

Psychopharmacology (Berl)
Vendruscolo LF, Vendruscolo JCM, Whiting KE, Acri JB, Volkow ND, Koob GF.   +5 more
europepmc   +1 more source

Identification of c[D-Trp-Phe-β-Ala-β-Ala], the First κ-Opioid Receptor-Specific Negative Allosteric Modulator. [PDF]

ACS Pharmacol Transl Sci
Zhao J, Baiula M, Cuna E, Francescato M, Matalińska J, Lipiński PFJ, Bedini A, Gentilucci L.   +7 more
europepmc   +1 more source

Depression-like effects induced by chronic unpredictable mild stress in mice are rapidly reversed by a partial negative allosteric modulator of mGlu₅ receptor, M-5MPEP. [PDF]

Psychopharmacology (Berl)
Pałucha-Poniewiera A, Bobula B, Rafało-Ulińska A, Kaczorowska K.   +3 more
europepmc   +1 more source

Basmisanil, an α5-GABA_AR negative allosteric modulator, produces rapid and sustained antidepressant-like responses in male mice. [PDF]

Neurosci Lett
Daher F, Villalobos NA, Hanley M, Atack JR, Popa MO, Fogaça MV.   +5 more
europepmc   +1 more source

The metabotropic glutamate receptor 5 negative allosteric modulator fenobam: pharmacokinetics, side effects, and analgesic effects in healthy human subjects. [PDF]

Pain, 2020
Cavallone LF, Montana MC, Frey K, Kallogjeri D, Wages JM, Rodebaugh TL, Doshi T, Kharasch ED, Gereau RW.   +8 more
europepmc   +1 more source

The CB1 negative allosteric modulator PSNCBAM-1 reduces ethanol self-administration via a nonspecific hypophagic effect. [PDF]

Pharmacol Biochem Behav
Buechler HM, Sumi M, Madhuranthakam IM, Donegan C, DiGiorgio F, Acosta AA, Uribe S, Rahman MA, Sorbello A, Fischer BD, Keck TM.   +10 more
europepmc   +1 more source