Results 41 to 50 of about 4,431,914 (288)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Global Sustainability, 2021 Non-technical summary Negative emissions technologies (NETs) have received increasing interest in recent years as a potential part of a portfolio of measures to address anthropogenic climate change, in particular following the 2015 UN Framework ...
Judith Kreuter, Markus Lederer
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Removing Carbon Now: How can companies and individuals fund negative emissions technologies in a safe and effective way to help solve the climate crisis? [PDF]
, 2020 Carbon removals are an important part of the solution of the climate crisis, hundreds of gigatons of CO2 will likely need to be removed from the atmosphere this century with the help of a wide range of negative emission technologies.
Höglund, Robert
core +1 more source
Environmental Research Letters, 2018 There are major concerns about the sustainability of large-scale deployment of carbon dioxide removal (CDR) technologies. It is therefore an urgent question to what extent CDR will be needed to implement the long term ambition of the Paris Agreement ...
Jessica Strefler +5 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Negative emissions—Part 3: Innovation and upscaling
Environmental Research Letters, 2018 We assess the literature on innovation and upscaling for negative emissions technologies (NETs) using a systematic and reproducible literature coding procedure.
Gregory F Nemet +9 more
doaj +1 more source
Frontiers in Climate, 2022 Mangrove forests, seagrass meadows and tidal saltmarshes are vegetated coastal ecosystems that accumulate and store large quantities of carbon in their sediments.
Phillip Williamson +3 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source