Results 41 to 50 of about 101,829 (247)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Negative emissions—Part 3: Innovation and upscaling

open access: yesEnvironmental Research Letters, 2018
We assess the literature on innovation and upscaling for negative emissions technologies (NETs) using a systematic and reproducible literature coding procedure.
Gregory F Nemet   +9 more
doaj   +1 more source

Carbon Removal Using Coastal Blue Carbon Ecosystems Is Uncertain and Unreliable, With Questionable Climatic Cost-Effectiveness

open access: yesFrontiers in Climate, 2022
Mangrove forests, seagrass meadows and tidal saltmarshes are vegetated coastal ecosystems that accumulate and store large quantities of carbon in their sediments.
Phillip Williamson   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Assessment of reasonable opportunities for direct air capture

open access: yesEnvironmental Research Letters, 2017
This work explores the possibility of using CO _2 captured directly from the atmosphere for several applications that require low to moderate purities.
Jennifer Wilcox   +2 more
doaj   +1 more source

Mineral–Soil–Plant–Nutrient Synergisms of Enhanced Weathering for Agriculture: Short-Term Investigations Using Fast-Weathering Wollastonite Skarn

open access: yesFrontiers in Plant Science, 2022
Enhanced weathering is a proposed carbon dioxide removal (CDR) strategy to accelerate natural carbon sequestration in soils via the amendment of silicate rocks to agricultural soils.
Hiral Jariwala   +4 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

The effectiveness of net negative carbon dioxide emissions in reversing anthropogenic climate change

open access: yesEnvironmental Research Letters, 2015
Artificial removal of CO _2 from the atmosphere (also referred to as negative emissions) has been proposed as a means to restore the climate system to a desirable state, should the impacts of climate change become ‘dangerous’.
Katarzyna B Tokarska, Kirsten Zickfeld
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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