Results 51 to 60 of about 1,131,290 (276)

Negative-continuum dielectronic recombination into excited states of highly-charged ions

, 2009
The recombination of a free electron into a bound state of bare, heavy nucleus under simultaneous production of bound-electron--free-positron pair is studied within the framework of relativistic first--order perturbation theory. This process, denoted as "
Artemyev, A. N., Shabaev, V. M., Stöhlker, Th., Surzhykov, A. S.   +3 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Criticality in confined ionic fluids

, 2001
A theory of a confined two dimensional electrolyte is presented. The positive and negative ions, interacting by a $1/r$ potential, are constrained to move on an interface separating two solvents with dielectric constants $\epsilon_1$ and $\epsilon_2$. It
A.Z. Panagiotopoulos, D.A. McQuarrie, E.S. Velazquez, E.Z. Güntelberg, G. Orkoulas, H. Weingärtner, I.S. Jacobs, J. E. Flores-Mena, J. Valleau, J.-M. Caillol, J.C. Shelley, J.J. Weis, J.J. Weis, J.M. Cailol, J.M. Cailol, J.P. Valleau, M.E. Fisher, M.E. Fisher, M.E. van Leeuwen, M.J. Stevens, Marcia C. Barbosa, N. Bjerrum, P. Pincus, P.J. Camp, P.W. Debye, Q. Yan, R.A. Salkar, R.P. Sear, R.R. Singh, T. Narayanan, T. Tlusty, W. Ebeling, W. Schröer, Y. Levin, Y. Levin, Y. Levin, Yan Levin   +36 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Sterilization Effect and Mechanism of Negative Ions in Refrigerator [PDF]

Shipin Kexue
In this study, Staphylococcus, Candida and Penicillium that had been isolated and purified from commercial salmon, chicken breast and citrus in our laboratory were used as target microorganisms to explore the sterilization effect and mechanism of ...
HU Haimei, JIANG Feng, CHEN Kaisong, LIU Gangshuai, JIA Wen, FU Daqi
doaj   +1 more source

EFFECT OF Ca2+ AND Mg2+ IONS ON THE REVERSE CATIONIC FLOTATION OF ITABIRITIC IRON ORE

Holos, 2021
In this work the effect of the Ca2+ and Mg2+ ions, added as salts of chlorine, on the reverse cationic flotation at pH 10.5 of an itabiritic iron ore sample was evaluated.
Daniel Geraldo da Cruz, Paola Suzane Moreira Gonçalves, Deisiane Ferreira Lelis, Rosa Malena Fernandes Lima   +3 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Many-body theory calculations of positron binding to negative ions [PDF]

, 2010
A many-body theory approach developed by the authors [Phys. Rev. A 70, 032720 (2004)] is applied to positron bound states and annihilation rates in atomic systems.
Gribakin, G. F., Ludlow, J. A.
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source