Results 81 to 90 of about 427,941 (305)
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Precision measurements on negative ions
In this thesis, experiments with negative ions performed at the DESIREE facility are presented. DESIREE consists of two electrostatic storage rings operated at 13 K.
Kristiansson, Moa
core
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Generation of hydrogen ionic plasma superimposed with positive ion beam
In this study, a hydrogen ionic plasma with relatively low residual fractional electron concentration (ne/n+ ∼ 10−2) is generated using an aluminum plasma grid for the production of negative hydrogen ions and a control grid for negative ion extraction ...
W. Oohara +7 more
doaj +1 more source
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
This paper presents a survey of methods, commonly in use or under development, to produce beams of polarized negative ions for injection into accelerators.
Haeberli, W.
core
Electrolyte Concentration in Urine and Urinary Infection—Is There Any Relation?
Background: Sodium, potassium, chloride, calcium, and magnesium in urine are useful biomarkers and are commonly evaluated in patients with different conditions. Urinary tract infections are among the most common diseases worldwide.
Ana Rita Ferrão +5 more
doaj +1 more source
Effects of Nonextensive Electrons on Dust-Ion Acoustic Waves in a Collisional Dusty Plasma with Negative Ions. [PDF]
Liu Z.
europepmc +1 more source
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
We review some of the recent progress in the studies of alkaline-earth, negative ions. Computations of autodetachment rates, electron affinities and transition wavelengths are discussed and some new and improved results are ...
Brage, T.
core

