Results 61 to 70 of about 152,323 (343)
Molecular Oncology, EarlyView.Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu +11 more
wiley +1 more source
NEGATIVE PRESSURE WOUND THERAPY (NPWT) FOR THE MANAGEMENT OF DIABETIC FOOT WOUND
Jurnal Ilmiah Kesehatan, 2015 Complications often experienced by people with diabetes are complications in the feet ( 15 % ) called diabetic foot ( Akhtyo , 2009) . Where the injury to the leg if not treated properly will lead to infections and ultimately need to be amputated .The ...
Wesiana Heris Santy
doaj +3 more sources
Behandeling van een chronische huidwonde bij een hond via negatieve druktherapie [PDF]
, 2016 A four-year-and-eight-month-old whippet was presented with a chronic skin wound situated at the medial aspect of the right elbow. Because of its chronic nature, the wound was initially carefully debrided and subsequently treated by means of negative ...
De Rooster, Hilde +5 more
core
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Negative pressure wound therapy: clinical utility
Chronic Wound Care Management and Research, 2015 Heidi Sandoz Accelerate CIC, Mile End Hospital, London, UK Abstract: Negative pressure wound therapy (NPWT), also known as topical negative pressure therapy, has been increasingly used in health care for the management of a wide variety of wounds over ...
Sandoz H
doaj
Journal of Pediatric Surgery Case Reports, 2021 Enterocutaneous fistula (ECF) is a serious complication with problems of nutritional maintenance, infection control and wound management. A preterm baby (birth weight 690g) developed ECF after surgery for necrotizing enterocolitis.
Chin-Yen Wu +4 more
doaj
Negative-pressure wound therapy for deep groin vascular infections [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2016 Introduction. Infection of synthetic graft in the groin is a rare but devastating complication. When it occurs, several possibilities of treatment are available.
Matić Predrag +9 more
doaj +1 more source
A case report of cutaneous mucormycosis of the hand after minor trauma in a patient with acute myeloid leukaemia [PDF]
, 2019 Background: Mucormycosis is a rare but life-threatening infection, caused by fungi of the Mucorales order, which can be found in soil, rotting leaves or on animals. Through characteristic angioinvasive growth, infections with mucor spores can occur as a
Maleitzke, Tazio +3 more
core +1 more source
Understanding and measuring mechanical signals in the tumor stroma
FEBS Open Bio, EarlyView.This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz +3 more
wiley +1 more source
The use of improvised negative pressure therapy to manage wounds in difficult situations at LAUTECH Teaching Hospital, Ogbomoso: a case series [PDF]
, 2022 Background: Creating an airtight seal is vital in making a Negative pressure wound therapy setup functional and effective but in some conditions, this may be difficult to achieve.
Ajibola, OF, Akanmu, AA, Ilori, OS
core +1 more source