Results 231 to 240 of about 9,303,620 (306)

Minimal Transport Units Govern Oxygen‐Defect Stabilization and Transport for Lightweight Solid Electrolytes

open access: yesAdvanced Science, EarlyView.
Lightweight borate chemistry combined with minimal transport units provides a new pathway for designing lightweight oxide‐ion solid electrolytes. ABSTRACT Solid electrolytes are central to electrochemical energy technologies, including fuel cells, sensors, catalysis, membrane separation, and electrolyser.
Xiaohui Li   +13 more
wiley   +1 more source

Organic Nanozyme‐Embedded Biotherapeutic Thermosensitive Hydrogel for Extracellular GSH Depletion and Postoperative Tumor Suppression

open access: yesAdvanced Science, EarlyView.
A temperature‐sensitive hydrogel loaded with cyanine nanozymes and Escherichia coli is locally injected into postoperative tumor resection beds. Upon light irradiation, synergistic PTT and PDT work with cascaded reactive oxygen species to deplete extracellular GSH, eliminate residual tumor cells, and induce robust antitumor immune responses for ...
Cong Jiang   +10 more
wiley   +1 more source

Observation of Magnetic‐Anisotropy Crossover and High‐Temperature Skyrmions in the Dirac Magnet Fe3Ge with a Distorted Kagome Lattice

open access: yesAdvanced Science, EarlyView.
A temperature‐driven magnetic anisotropy crossover is revealed in the Dirac kagome magnet Fe3Ge with a distorted kagome lattice. The transition from easy‐plane to easy‐axis magnetic anisotropy stabilizes robust Bloch‐type skyrmions over an exceptionally wide temperature window of 375–650 K.
Yalei Huang   +15 more
wiley   +1 more source

Targeting the PHB2–ACSL3 Lipid‐Remodeling Axis Overcomes Cisplatin Resistance by Restoring Ferroptosis in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
ABSTRACT Platinum‐based chemotherapy resistance remains a major obstacle in gastric cancer (GC) treatment. Through integrated transcriptomic profiling of cisplatin‐resistant xenografts and pharmacogenomic interrogation of the NCI‐60 dataset, we identified Prohibitin‐2 (PHB2) as a previously unrecognized determinant of chemoresistance.
Liang Xu   +10 more
wiley   +1 more source

AL398, A Novel NSUN6 Inhibitor, Attenuates Epithelial‐Mesenchymal Transition and Metastasis in Endometrial Cancer by Abrogating m5C‐Dependent Stabilization of Snail mRNA

open access: yesAdvanced Science, EarlyView.
Proposed molecular mechanism: NSUN6 catalyzes m5C methylation on Snail mRNA to enhance its stability, leading to Snail upregulation and EMT promotion. The first‐in‐class inhibitor AL398 suppresses endometrial cancer metastasis by targeting the NSUN6‐m5C‐Snail. axis. ABSTRACT Endometrial cancer (EC) constitutes a leading gynecologic malignancy for which
Xiangzhuan Zhao   +19 more
wiley   +1 more source

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