Results 221 to 230 of about 9,303,620 (306)

Striatal social reward sensitivity predicts trust-related brain responses depending on closeness and depression. [PDF]

Biol Psychol
Wang S, Yang Y, Sharp CJ, Fareri D, Chein J, Smith DV.   +5 more
europepmc   +1 more source

Photobiomodulation‑Engineered Extracellular Vesicles Enhance Neural Differentiation via UFL1‑Mediated UFMylation in Spinal Cord Injury

Advanced Science, EarlyView.
Photobiomodulated microglia release engineered extracellular vesicles that deliver UFL1 to the injured spinal cord. UFL1 competitively binds p53 with MDM2, inhibiting p53 ubiquitination and stabilizing p53 signaling. This dual mechanism simultaneously promotes anti‐inflammatory microglial polarization and directs neural stem cell differentiation toward
Yunxiao Fang, Zuomeng Wu, Ruocheng Guo, Cancan Wang, Yue Qin, Yixiang Dong, Aoyun Li, Ao Liu, Chongyu Jia, Tianyu Han, Peiwen Song, Lei Chen, Cailiang Shen   +12 more
wiley   +1 more source

Association of Motor Stereotypies with Emotional Dysregulation and Anxiety/Depression Symptoms in Children with Autism Spectrum Disorder. [PDF]

Children (Basel)
Hurtado Ruíz MG, Arranz Calderón MJ, Pérez Solá V, Prades Oropesa M, Hervás Zúñiga A.   +4 more
europepmc   +1 more source

Artificial Grain Boundaries Created by Freestanding Membrane Transfer Reveal Angle‐Dependent Ferroelectric Switching and Leakage in BaTiO3

Advanced Science, EarlyView.
Artificial grain boundaries are created in BaTiO3$\text{BaTiO}_3$ thin films by freestanding membrane transfer, enabling direct isolation of a single boundary. Local ferroelectric switching and leakage are found to concentrate at the grain boundary, while increasing misorientation systematically enhances conduction.
Shin‐Rou Yin, Yu‐Hsin Lin, Yun‐Guan Wei, Yu‐Cheng Fang, Yung‐Chi Su, Yu‐Wei Chen, Yu‐Ting Lin, Chia‐Chun Wei, Chih‐Hung Wu, Ching‐Yu Chiang, Heng‐Jui Liu, Jan‐Chi Yang, Yi‐Chun Chen, Yen‐Lin Huang   +13 more
wiley   +1 more source

A Micropeptide Component of the OGDH Complex Modulates ATP Production in the TCA Cycle

Advanced Science, EarlyView.
This study identified a mitochondrial micropeptide encoded by a non‐canonical open reading frame (alt‐ORF) within the CTSB gene. This micropeptide named APPM (ATP production‐promoting micropeptide) is a novel component of the OGDHc complex in the TCA cycle. APPM localizes to the inner mitochondrial membrane and directly binds to OGDH, the E1 subunit of
Xinqiang Yin, Weiyan Qi, Lifen Lin, Huilin Zheng, Guoxiang Zhao, Quan Chen, Guoqiang Shao, Yifan Wu, Jialiang Hu, Hanmei Xu   +9 more
wiley   +1 more source

Role of Maternal Mindfulness in Longitudinal Mother-Infant Neuroendocrine Reciprocity in an Urban, Low-Income White Sample. [PDF]

Dev Psychobiol
Suzuki K, Laurent H.
europepmc   +1 more source

Fzd7 Restrains Pink1‐Dependent Mitophagy in Suture Stem Cells to Maintain Cranial Suture Patency

Advanced Science, EarlyView.
How suture stem cells fail to preserve cranial suture patency remains incompletely understood. Integrated single‐cell and high‐resolution spatial transcriptomic analyses identify reduced Fzd7 expression in Prrx1+ suture stem cells as an early feature of craniosynostosis.
Xinyan Chen, Zong Chen, Chenzhi Lai, Yingying Yue, Tian He, Hao Gong, Jing Shi, Xiaoshuang Guo, Yu Wang, Guodong Song, Xiaolei Jin   +10 more
wiley   +1 more source

Negative emotions concentrate while positive emotions diffuse in football fan rivalries. [PDF]

PLoS One
Grund TU.
europepmc   +1 more source

TH17–Associated Polyamine Metabolism‐Guided Nanozyme Promotes Alveolar Bone Repair in Periodontitis

Advanced Science, EarlyView.
A pronounced TH17‐skewed immune response is identified in experimental periodontitis, and enrichment of the polyamine pathway is observed during TH17 differentiation, suggesting its potential as an immunometabolic target. Inspired by these findings, DFMO@Ui‐Mn is developed as a therapeutic platform combining cascade ROS scavenging with immunometabolic ...
Cheng Zhu, Tiancheng Li, Yu Jin, Yixin Li, Qicheng Liu, Runzhe Fang, Luyao Qu, Xinyue Tang, Ruomei Li, Xiaoyue Zhao, Jin Hao, Bing Fang, Lunguo Xia   +12 more
wiley   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source