Results 71 to 80 of about 9,303,620 (306)
Negative moments of orthogonal polynomials
Forum of Mathematics, Sigma, 2023 If a sequence indexed by nonnegative integers satisfies a linear recurrence without constant terms, one can extend the indices of the sequence to negative integers using the recurrence.
Jihyeug Jang +4 more
doaj +1 more source
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Exploring the Influence of Workplace Ostracism on Knowledge Hiding: The Mediating Effect of Reciprocal Beliefs [PDF]
نشریه مطالعات دانشپژوهیPurpose: This study investigates the impact of workplace ostracism on knowledge hiding, emphasizing the mediating role of reciprocity beliefs among library staff at the University of Tehran.Methodology: This research is descriptive and survey-based, and ...
Seifallah Andayesh
doaj +1 more source
Reciprocity of thermal diffusion in time-modulated systems
Nature Communications, 2022 The use of time modulation to break reciprocity is well understood for light, sound or charge diffusion, but it’s unclear whether it can work for thermal diffusion.
Jiaxin Li +10 more
doaj +1 more source
Emotional Feeding and Emotional Eating: Reciprocal Processes and the Influence of Negative Affectivity [PDF]
Child Development, 2018 Abstract Emotional eating, that is, eating more in response to negative mood, is often seen in children. But the origins of emotional eating remain unclear. In a representative community sample of Norwegian 4-year-olds followed up at ages 6, 8, and 10 years (analysis sample: n = 801), one potential developmental pathway was examined ...
Steinsbekk, S +4 more
openaire +8 more sources
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Reciprocity in parenting of adolescents within the context of marital negativity. [PDF]
Developmental Psychology, 2009 The authors investigated the degree to which parents become more similar to each other over time in their childrearing behaviors. Mothers and fathers of 451 adolescents were assessed at 3 points in time, with 2-year lags between each assessment. Data on parent warmth, harshness, and monitoring were collected by parent self-report, adolescent report ...
Thomas J. Schofield +5 more
openaire +2 more sources