Active Force Dynamics in Red Blood Cells Under Non‐Invasive Optical Tweezers
A non‐invasive method combines low‐power optical tweezers with high‐speed microscopy to simultaneously monitor local membrane forces and displacements in single human red blood cells. This dual‐channel approach reveals a mechano‐dynamic signature that correlates the cell's metabolic state with its mechanical activity. This energetic framework serves as
Arnau Dorn +5 more
wiley +1 more source
Consequences of Canada's Drug Agency Reimbursement Recommendations for New Medicines and Pan-Canadian Pharmaceutical Alliance Price Negotiations on Patient Access. [PDF]
Rawson NSB.
europepmc +1 more source
An Approach to the stability of international environmental agreements: the absorbing sets solution [PDF]
We study international environmental negotiations when agreements between countries can not be binding. A problem with this kind of negotiations is that countries have incentives for free-riding from such agreements.
Olaizola Sánchez, María Norma
core
A spectrally and kinetically multiplexed single‐molecule imaging method is developed, which achieved simultaneous imaging of 12 exosomal proteins at an unparalleled single‐copy resolution. It is found that co‐occurrence of α6 integrin and the pairing β counterpart on single exosomes is essential for lung targeting, providing valuable information for ...
Songlin Liu +10 more
wiley +1 more source
From Glasgow to Belém: bringing health to the COP climate negotiations. [PDF]
Straif K, Gouveia N.
europepmc +1 more source
General schematic of the approach. Abstract Conventional Silver/Silver Chloride (Ag/AgCl) electrodes remain the clinical standard for electrophysiological monitoring but are hindered by poor skin conformity, mechanical rigidity, and signal degradation, particularly under motion or sweat.
Nazmi Alsaafeen +11 more
wiley +1 more source
Label‐Free Molecular Characterization of Protein Aggregates in Differentiated Astrocytes
Mid‐infrared photothermal microscopy enables label‐free structural, molecular, and functional imaging of protein aggregates in astrocyte cells. The processes of astrocytes differentiated on a nanomaterial interface are characterized by α‐helical signatures combined with enhanced interfacial thermal resistance properties, while the cell soma of non ...
Panagis D. Samolis +9 more
wiley +1 more source
Domestication as Stabilisation: Exploring the Incorporation of Social Technology by Older Adults and Their Relatives. [PDF]
Bavngaard MV, Lund A, Rasmussen EB.
europepmc +1 more source
GOT1 Inhibition Induces Extracellular Matrix Remodeling in Pancreatic Cancer
Using tumor tissue engineering, we recreated pancreatic cancer and found that inhibiting glutamic‐oxaloacetic transaminase 1 (GOT1) induces extracellular matrix remodeling and secretome rewiring, as well as promotes cell death. ABSTRACT Pancreatic cancer cells rely on glutamine to sustain their survival in the stiff and poorly vascularized tumor ...
Rodrigo Curvello +10 more
wiley +1 more source
Health and Climate at COP29: Advancing Integration and Bridging Research Gaps. [PDF]
Patel RR +4 more
europepmc +1 more source

