Results 121 to 130 of about 359,204 (312)

Rhinovirus infection and co-infection in children with severe acute respiratory infection during the COVID-19 pandemic period

open access: yesVirulence
Rhinovirus causes respiratory tract infections in children and is found in co-infections. The objective of this research was to study the clinical profile of rhinovirus infection and co-infection in children with severe acute respiratory infection (SARI)
Célia Regina Malveste Ito   +12 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Neighborhood Context, Poverty, and Urban Children’s Outdoor Play [PDF]

open access: yes
Although research consistently demonstrates a link between neighborhood conditions and physical activity for adults and adolescents, less is known about residential context and young children’s physical activity.
Sara McLanahan   +2 more
core  

On the Size of the Neighborhoods of a Word

open access: yesIEEE Transactions on Computational Biology and Bioinformatics
The d-neighborhood of a word W in the Levenshtein distance is the set of all words at distance at most d from W. Generating the neighborhood of a word W, or related sets of words such as the condensed neighborhood or the super-condensed neighborhood has applications in the design of approximate pattern matching algorithms. It follows that bounds on the
Cédric Chauve, Louxin Zhang
openaire   +3 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Sliding down the socioeconomic health gradient of COVID-19 in New York City: multinomial regression analyses of disproportionate financial hardship for Black, Latino, and Asian residents and households with children

open access: yesFrontiers in Public Health
BackgroundDistinct socioeconomic gradients in COVID-19 outcomes were observed across the United States, so an evaluation of individual resident characteristics related to economic deprivation (race or ethnicity, precarious employment, children in the ...
Rose Jimenez   +8 more
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Low-income housing tax credit developments and neighborhood property conditions [PDF]

open access: yes
Public housing has long been a contentious issue for cities and regions. While there is a great need for affordable housing in many communities, neighbors of low-income housing developments fret about neighborhood decay.
Kelly D. Edmiston
core  

A One-Year Retrospective Observational Study of an Occupational Medicine Outpatient Clinic in a City Hospital

open access: yesAnnals of Global Health
Background: Occupational diseases (ODs) remain a major public health concern. Despite advances in occupational health (OH), many workers remain at risk due to insufficient preventive measures and limited access to specialized care.
Yusuf Samir Hasanli
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

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