Results 1 to 10 of about 91,150 (302)
PLoS Pathogens, 2020 It is increasingly being recognised that the interplay between commensal and pathogenic bacteria can dictate the outcome of infection. Consequently, there is a need to understand how commensals interact with their human host and influence pathogen ...
Rafael Custodio +4 more
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Cefotaxime-Resistant Neisseria meningitidis Sequence Type 4821 Causing Fulminant Meningitis [PDF]
Emerging Infectious DiseasesWe explored the role of commensal Neisseria in the emergence of third-generation cephalosporin-resistant N. meningitidis. Cefotaxime resistance–conferring penA795 was prevalent among commensal Neisseria isolates in Shanghai, China, and was acquired by a
Youxing Shao +7 more
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Genome wide expression profiling reveals suppression of host defence responses during colonisation by Neisseria meningitides but not N. lactamica. [PDF]
PLoS ONE, 2011 Both Neisseria meningitidis and the closely related bacterium Neisseria lactamica colonise human nasopharyngeal mucosal surface, but only N. meningitidis invades the bloodstream to cause potentially life-threatening meningitis and septicaemia.
Hazel En En Wong +4 more
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An Overview of Neisseria meningitidis
Methods in molecular biology, 2019 Neisseria meningitidis (the meningococcus) is a member of the normal nasopharyngeal microbiome in healthy individuals, but can cause septicemia and meningitis in susceptible individuals. In this chapter we provide an overview of the disease caused by N. meningitidis and the schemes used to type the meningococcus. We also review the adhesions, virulence
Hollingshead, S, Tang, C
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Recognition of Neisseria meningitidis by the long pentraxin PTX3 and its role as an endogenous adjuvant. [PDF]
PLoS ONE, 2015 Long pentraxin 3 (PTX3) is a non-redundant component of the humoral arm of innate immunity. The present study was designed to investigate the interaction of PTX3 with Neisseria meningitidis.
Barbara Bottazzi +14 more
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Metabolism and virulence in Neisseria meningitidis [PDF]
Frontiers in Cellular and Infection Microbiology, 2014 A longstanding question in infection biology addresses the genetic basis for invasive behavior in commensal pathogens. A prime example for such a pathogen is Neisseria meningitidis. On the one hand it is a harmless commensal bacterium exquisitely adapted to humans, and on the other hand it sometimes behaves like a ferocious pathogen causing potentially
Schoen, Christoph +3 more
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The comparative population genetics of Neisseria meningitidis and Neisseria gonorrhoeae [PDF]
PeerJ, 2019 Neisseria meningitidis and N. gonorrhoeae are closely related pathogenic bacteria. To compare their population genetics, we compiled a dataset of 1,145 genes found across 20 N. meningitidis and 15 N. gonorrhoeae genomes. We find that N.
Eyre-Walker, Adam, Vigué, Lucile
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Neisseria meningitidis: pathogenesis and immunity
Current Opinion in Microbiology, 2015 The recent advances in cellular microbiology, genomics, and immunology has opened new horizons in the understanding of meningococcal pathogenesis and in the definition of new prophylactic intervention. It is now clear that Neissera meningitidis has evolved a number of surface structures to mediate interaction with host cells and a number of mechanisms ...
Pizza, Mariagrazia, Rappuoli, Rino
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Outbreak of Sexually Transmitted Nongroupable Neisseria meningitidis–Associated Urethritis, Vietnam [PDF]
Emerging Infectious Diseases, 2023 We report on an outbreak of nongroupable Neisseria meningitidis–associated urethritis, primarily among men who have sex with men in southern Vietnam. Nearly 50% of N. meningitidis isolates were resistant to ciprofloxacin.
Hao Trong Nguyen +17 more
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Rifampin-resistant Neisseria meningitidis
Emerging Infectious Diseases, 2006 To the Editor: Immediate management of meningococcal disease requires antimicrobial drug treatment of patients with β-lactams and chemoprophylaxis of contact persons with rifampin. High-level resistance to rifampin (MIC >32 mg/L) in Neisseria meningitidis is provoked by mutations (most frequently at the residue His 552) in the rpoB gene encoding the b ...
Muhamed-Kheir Taha +4 more
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