Genome wide expression profiling reveals suppression of host defence responses during colonisation by Neisseria meningitides but not N. lactamica. [PDF]
Both Neisseria meningitidis and the closely related bacterium Neisseria lactamica colonise human nasopharyngeal mucosal surface, but only N. meningitidis invades the bloodstream to cause potentially life-threatening meningitis and septicaemia.
Hazel En En Wong+4 more
doaj +4 more sources
Internalization of Lactobacillus crispatus Through Caveolin-1-Mediated Endocytosis Boosts Cellular Uptake but Blocks the Transcellular Passage of Neisseria meningitidis [PDF]
Neisseria meningitidis is a human-specific pathogen that colonizes the nasopharyngeal epithelium, which is populated by a dynamic microbiota that includes Lactobacillus species.
Kenny Lidberg+3 more
doaj +2 more sources
Clonal analysis of meningococci during a 26 year period prior to the introduction of meningococcal serogroup C vaccines [PDF]
Meningococcal disease remains a public health burden in the UK and elsewhere. Invasive Neisseria meningitidis, isolated in Scotland between 1972 and 1998, were characterised retrospectively to examine the serogroup and clonal structure of the circulating
Clarke, Stuart C.+3 more
core +26 more sources
Background: Neutrophils are an essential part of innate immunity and play a crucial role in controlling infection caused by Neisseria meningitidis.
Abdel-Rahman Youssef
doaj +1 more source
A rare complication of Neisseria meningitidis is pericarditis. Here a 74-year-old male with Neisseria meningitidis serogroup W(P1.5−2) presented with myopericarditis.
Michael Platten, Layth Aladellie
doaj +1 more source
Development of a SimpleProbe real-Time PCR Assay for rapid detection and identification of the US novel urethrotropic clade of Neisseria meningitidis ST-11 (US_NmUC) [PDF]
Urethritis, or inflammation of the urethra, is one of the most common reasons men seek clinical care. Sexually transmitted pathogens including Neisseria gonorrhoeae are responsible for over half of the symptomatic urethritis cases in U.S. men.
Ermel, Aaron+4 more
core +1 more source
Development of Lipid Nanoparticles [LNP]-RNA Vaccine Against Neisseria Meningitidis CPS Gene Locus Facilitating the Synthesis of The Capsular Polysaccharide in Egypt [PDF]
Background: Neisseria meningitidis meningitis is a dangerous, widespread illness in Egypt nowadays. Immunity lasts a long time. Worldwide, meningitis and meningococcemia, which are caused by Neisseria meningitidis, are the leading infectious causes of ...
Mohammed Kassab
doaj +1 more source
Genealogical typing of Neisseria meningitidis [PDF]
Despite the increasing popularity of multilocus sequence typing (MLST), the most appropriate method for characterizing bacterial variation and facilitating epidemiological investigations remains a matter of debate. Here, we propose that different typing schemes should be compared on the basis of their power to infer clonal relationships and investigate
Didelot, X+3 more
openaire +5 more sources
Neisseria meningitidis-induced acute systemic meningococcal disease is an emergency and a fatal condition that has a high mortality rate. In patients with a fulminant infection, a maculopapular petechial eruption, purpura fulminans, or an ecchymotic ...
Meng-Yu Wu+5 more
doaj +1 more source
Potchefstroom experienced an outbreak of Neisseria meningitidis (N. meningitidis) during May-July 2003. An opportunity for obtaining valuable data arose when mass prophylactic treatment to approximately 28% of the Potchefstroom community was provided by ...
Michelle Viljoen+2 more
doaj +1 more source