Results 21 to 30 of about 93,162 (292)

Neisseria meningitidis Induced Fatal Waterhouse–Friderichsen Syndrome in a Patient Presenting With Disseminated Intravascular Coagulation and Multiple Organ Failure

Brain Sciences, 2020
Neisseria meningitidis-induced acute systemic meningococcal disease is an emergency and a fatal condition that has a high mortality rate. In patients with a fulminant infection, a maculopapular petechial eruption, purpura fulminans, or an ecchymotic ...
Meng-Yu Wu, Chien-Sheng Chen, Chih-Yi Tsay, Giou-Teng Yiang, Jian-Yu Ke, Po-Chen Lin   +5 more
doaj   +1 more source

Expression of phosphofructokinase in Neisseria meningitidis [PDF]

Microbiology, 2010
Neisseria meningitidisserogroup B is a pathogen that can infect diverse sites within the human host. According to theN. meningitidisgenomic information and experimental observations, glucose can be completely catabolized through the Entner–Doudoroff pathway and the pentose phosphate pathway. The Embden–Meyerhof–Parnas pathway is not functional, because
Baart, G.J.E., Langenhof, M., van de Waterbeemd, B., Hamstra, H.J., Zomer, B., van der Pol, L.A., Beuvery, E.C., Tramper, J., Martens, D.E.   +8 more
openaire   +5 more sources

Towards the Immunoproteome of Neisseria meningitidis [PDF]

PLoS ONE, 2009
Despite the introduction of conjugated polysaccharide vaccines for many of the Neisseria meningitidis serogroups, neisserial infections continue to cause septicaemia and meningitis across the world. This is in part due to the difficulties in developing a, cross-protective vaccine that is effective against all serogroups, including serogroup B ...
Mendum, TA, Newcombe, J, McNeilly, CL, McFadden, J   +3 more
openaire   +6 more sources

Detailed evaluation of data analysis tools for subtyping of bacterial isolates based on whole genome sequencing : Neisseria meningitidis as a proof of concept [PDF]

, 2019
Whole genome sequencing is increasingly recognized as the most informative approach for characterization of bacterial isolates. Success of the routine use of this technology in public health laboratories depends on the availability of well-characterized ...
Bertrand, Sophie, De Keersmaecker, Sigrid CJ, Marchal, Kathleen, Mattheus, Wesley, Roosens, Nancy HC, Saltykova, Assia   +5 more
core   +1 more source

The Neisseria meningitidis CRISPR-Cas9 System Enables Specific Genome Editing in Mammalian Cells

Molecular Therapy, 2016
The clustered regularly-interspaced short palindromic repeats (CRISPR)—CRISPR-associated (Cas) system from Streptococcus pyogenes (Spy) has been successfully adapted for RNA-guided genome editing in a wide range of organisms.
Ciaran M. Lee, T. Cradick, Gang Bao
semanticscholar   +1 more source

Early-onset neonatal sepsis caused by Neisseria meningitidis serogroup B: case report and literature review of a 102-year period

The Turkish Journal of Pediatrics, 2020
A 36-week-2-day-old male infant was admitted to the neonatal unit with respiratory distress, hypoglycaemia and suspected early onset neonatal sepsis for respiratory support, monitoring and intravenous antibiotics.
Tayyib Mubashar, Paul Christopher Turner, Siba Prosad Paul   +2 more
doaj   +1 more source

Bacterial outer membrane vesicles and vaccine applications [PDF]

, 2014
Vaccines based on outer membrane vesicles (OMV) were developed more than 20 years ago against Neisseria meningitidis serogroup B. These nano-sized structures exhibit remarkable potential for immunomodulation of immune responses and delivery of “self ...
Acevedo, Reinaldo, Acosta, Armando, Campa, Concepcion, Cardoso, Daniel, Fernandez, Sonsire, Ferro, Valerie, Garcia, Luis, Perez, Jose Luis, Rosenqvist, Einar, Sarmiento, Maria Elena, Zayas, Caridad   +10 more
core   +2 more sources

Expansion of a urethritis-associated Neisseria meningitidis clade in the United States with concurrent acquisition of N. gonorrhoeae alleles

BMC Genomics, 2018
BackgroundIncreased reports of Neisseria meningitidis urethritis in multiple U.S. cities during 2015 have been attributed to the emergence of a novel clade of nongroupable N. meningitidis within the ST-11 clonal complex, the “U.S. NmNG urethritis clade”.
Adam C. Retchless, C. Kretz, J. Bazan, Jeanine Abrams, C. Kretz, How-Yi Chang, A. J. Abrams, A. N. Turner, Laurel T Jenkins, D. Trees, Yih-Ling Tzeng, D. Stephens, Jessica R Macneil, Xin Wang   +13 more
semanticscholar   +1 more source

Structure of the Neisseria meningitidis Type IV pilus

Nature Communications, 2016
Neisseria meningitidis use Type IV pili (T4P) to adhere to endothelial cells and breach the blood brain barrier, causing cause fatal meningitis. T4P are multifunctional polymers of the major pilin protein, which share a conserved hydrophobic N terminus ...
S. Kolappan, Mathieu Coureuil, Xiong Yu, X. Nassif, E. Egelman, L. Craig   +5 more
semanticscholar   +1 more source

Cocirculation of Hajj and non-Hajj strains among serogroup W meningococci in Italy, 2000 to 2016 [PDF]

, 2019
In Italy, B and C are the predominant serogroups among meningococci causing invasive diseases. Nevertheless, in the period from 2013 to 2016, an increase in serogroup W Neisseria meningitidis (MenW) was observed.
Arghittu M., Barbui A. M., Bernaschi P., Bisbano A., Chironna M., Ciammaruconi A., De Nittis R., Fazio C., Galanti I. A., Giammanco A., Isola P., Mencacci A., Neri A., Pagani E., Stefanelli P., Vacca P., Vocale C.   +16 more
core   +1 more source