Results 81 to 90 of about 93,162 (292)

Pseudomonas aeruginosa LptE is crucial for LptD assembly, cell envelope integrity, antibiotic resistance and virulence [PDF]

, 2018
Lipopolysaccharide (LPS) is an essential structural component of the outer membrane (OM) of most Gram-negative bacteria. In the model organism Escherichia coli, LPS transport to the OM requires seven essential proteins (LptABCDEFG) that form a continuous
Fernández-Piñar, Regina, Imperi, Francesco, Lo Sciuto, Alessandra, Mancone, Carmine, Martorana, Alessandra M., Polissi, Alessandra   +5 more
core   +3 more sources

Nasal Inoculation of the Commensal Neisseria lactamica Inhibits Carriage of Neisseria meningitidis by Young Adults: A Controlled Human Infection Study.

Clinical Infectious Diseases, 2015
BACKGROUND Herd protection by meningococcal vaccines is conferred by population-level reduction of meningococcal nasopharyngeal colonization. Given the inverse epidemiological association between colonization by commensal Neisseria lactamica and ...
A. Deasy, E. Guccione, Adam P. Dale, N. Andrews, C. Evans, Julia S. Bennett, H. Bratcher, M. Maiden, A. Gorringe, R. Read   +9 more
semanticscholar   +1 more source

Trends in Paediatric Viral Meningitis and Encephalitis With Unconfirmed Aetiology: A Spanish Population‐Based Study, 2016–2020

Acta Paediatrica, EarlyView.
ABSTRACT Aim The prevalence of meningitis and encephalitis of unknown aetiology in Spanish children has not been specifically documented before. The aim of this study is to describe the epidemiology and trends of these clinical conditions between 2016 and 2020.
Marina Pons‐Espinal, Noemi López‐Perea, Josefa Masa‐Calles, Carmen Muñoz‐Almagro, David Tarragó, Cristian Launes   +5 more
wiley   +1 more source

Pericarditis due to Neisseria meningitidis serogroup W135

IDCases, 2018
Neisseria meningitidis is a well-recognized cause of bacterial meningitis. Although less common, N. meningitidis can also involve extra-meningeal sites, including the pericardium.
Takashi Shinha, Hiroshi Fujita
doaj  

Efficacy and safety of HRS‐5965 monotherapy in complement inhibitor–naïve patients with paroxysmal nocturnal haemoglobinuria

British Journal of Haematology, EarlyView.
Summary Paroxysmal nocturnal haemoglobinuria (PNH) is a rare, life‐threatening disorder characterized by complement‐mediated haemolysis, leading to anaemia and thrombosis. HRS‐5965 is a novel, oral, selective complement factor B inhibitor targeting the alternative pathway, potentially reducing both intra‐ and extravascular haemolysis.
Li Zhang, Ziwei Liu, Xin Zhao, Bin Hu, Rong Huang, Chang Shu, Fengkui Zhang, Bing Han   +7 more
wiley   +1 more source

Pharyngeal carriage of Neisseria species in the African meningitis belt. [PDF]

, 2016
OBJECTIVES: Neisseria meningitidis, together with the non-pathogenic Neisseria species (NPNs), are members of the complex microbiota of the human pharynx.
Ali, Oumer A, Aseffa, Abraham, Bennett, Julia S, Borrow, Ray, Bugri, Akalifa, Collard, Jean-Marc, Dano, Ibrahim D, Daugla, Doumagoum M, Diallo, Aldiouma, Diallo, Kanny, Dieng, Marietou, Gadzama, Galadima, Gamougam, Kadidja, Greenwood, Brian M, Issaka, Bassira, Maiden, Martin CJ, Manigart, Olivier, Mbainadji, Lodoum, Mihret, Adane, Nascimento, Maria, Omotara, Babatunji A, Osei, Isaac, Quaye, Stephen L, Rebbetts, Lisa S, Sambo, Zailani B, Sow, Samba O, Stuart, James M, Tamboura, Boubou, Timbine, Youssouf, Trotter, Caroline, Watkins, Eleanor R, Woukeu, Arouna   +31 more
core   +1 more source

Is Rifampin (Rifampicin) Essential for the Treatment of Rhodococcus equi Infections in Foals? A Critical Review of the Role of Rifampin

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Rifampin is an enigma among antimicrobials. Blood and tissue compartment concentrations are a “moving target” along the treatment course due to the complex pharmacodynamic interactions within the body. Rifampin concomitant therapies are for the prevention and treatment of Rhodococcus equi infection in foals, for nearly 40 years.
Keith Edward Baptiste, Niels Christian Kyvsgaard, Mohamed Omar Ahmed, Peter Damborg, Patricia M. Dowling   +4 more
wiley   +1 more source

Polyhydroxyalkanoate beads as a particulate vaccine against Streptococcus pneumoniae and Neisseria meningitidis : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Microbiology at Massey University, Manawatu, New Zealand [PDF]

, 2017
Listed in 2018 Dean's List of Exceptional ThesesStreptococcus pneumoniae and Neisseria meningitidis are the major causes of pneumonia and meningitis, respectively, worldwide.
González Miró, Majela
core  

Detection of recombination in DNA multiple alignments with hidden markov models [PDF]

, 2001
CConventional phylogenetic tree estimation methods assume that all sites in a DNA multiple alignment have the same evolutionary history. This assumption is violated in data sets from certain bacteria and viruses due to recombination, a process that leads
Dempster A.P., Dirk Husmeier, Frank Wright   +2 more
core   +2 more sources

Clinical Evaluation of a Loop-Mediated Isothermal Amplification (LAMP) Assay for Rapid Detection of Neisseria meningitidis in Cerebrospinal Fluid

PLoS ONE, 2015
Background Neisseria meningitidis (Nm) is a leading causative agent of bacterial meningitis in humans. Traditionally, meningococcal meningitis has been diagnosed by bacterial culture. However, isolation of bacteria from patients’ cerebrospinal fluid (CSF)
Dokyung Lee, E. J. Kim, P. Kilgore, S. A. Kim, Hideyuki Takahashi, M. Ohnishi, D. Anh, B. Dong, J. S. Kim, J. Tomono, Shigehiko Miyamoto, T. Notomi, D. W. Kim, M. Seki   +13 more
semanticscholar   +1 more source