Results 121 to 130 of about 4,593,278 (410)

Neoadjuvant eribulin mesylate following anthracycline and taxane in triple negative breast cancer: Results from the HOPE study [PDF]

, 2019
Background Eribulin mesylate (E) is indicated for metastatic breast cancer patients previously treated with anthracycline and taxane. We argued that E could also benefit patients eligible for neoadjuvant chemotherapy. Methods Patients with primary triple
Apolone G., Bianchi G. V., Cazzaniga M. E., Colombo M. P., Cosimo S. D., Crippa F., de Braud F., De Santis M. C., Folli S., Generali D., Gulino A., Mariani L., Moretti A., Nicola M. D., Paolini B., Scaperrotta G., Torri V., Tripodo C., Verde N. L.   +18 more
core   +2 more sources

Blood Biomarker‐Based Predictive Indicator for Liver Metastasis in Alpha‐Fetoprotein‐Producing Gastric Cancer and Multi‐Omics Tumor Microenvironment Insights

Advanced Science, EarlyView.
Alpha‐fetoprotein‐producing gastric cancer (AFPGC), a rare and aggressive subtype of gastric cancer, presents a high risk of liver metastasis. This study introduces the ANLiM score, a blood biomarker‐based predictive indicator for assessing liver metastasis and immunotherapy response.
Yongfeng Ding, Yiran Chen, Jing Zhang, Qingrui Wang, Songting Zhu, Junjie Jiang, Chao He, Jincheng Wang, Laizhen Tou, Jingwei Zheng, Bicheng Chen, Sizhe Hu, Xiongfei Yu, Haohao Wang, Yimin Lu, Mei Kong, Yanyan Chen, Haiyong Wang, Haibin Zhang, Hongxia Xu, Fei Teng, Xian Shen, Nong Xu, Jian Ruan, Zhan Zhou, Jun Lu, Lisong Teng   +26 more
wiley   +1 more source

NEOADJUVANT ENDOCRINE THERAPY FOR PATIENTS WITH ESTROGEN-RECEPTOR-POSITIVE BREAST CANCER

Сибирский онкологический журнал, 2018
More than 70 % of patients with breast cancer have estrogen-receptor-positive tumors (ER+) and are considered hormone- sensitive. That is why a vast majority of patients with early operable  tumors receive adjuvant endocrine therapy.
V. F. Semiglazov, V. V. Semiglazov, G. A. Dashyan, P. V. Krivorotko, V. G. Ivanov, E. K. Zhiltsova, R. M. Paltuev, L. M. Bershtein, T. Yu. Semiglazova, S. S. Yerechshenko, V. V. Klimenko, V. S. Apollonova, A. V. Komyahov, A. A. Bessonov   +13 more
doaj   +1 more source

Diffusion Tensor Imaging for Assessment of Response to Neoadjuvant Chemotherapy in Patients With Breast Cancer. [PDF]

, 2016
In this study, the prognostic significance of tumor metrics derived from diffusion tensor imaging (DTI) was evaluated in patients with locally advanced breast cancer undergoing neoadjuvant therapy.
Harnish, Roy, Hylton, Nola M, Li, Wen, Newitt, David C, Proctor, Evelyn, Shin, Hee Jung, Wilmes, Lisa J   +6 more
core   +1 more source

Survival benefit of adjuvant therapy completion with early initiation for patients with pancreatic ductal adenocarcinoma

Annals of Gastroenterological Surgery, EarlyView.
Adjuvant completion with early initiation may contribute to the improved survival of patients with pancreatic ductal adenocarcinoma. Abstract Aim To evaluate the prognostic effect of initiation timing and completion of adjuvant therapy in patients with pancreatic ductal adenocarcinoma.
Kenjiro Okada, Kenichiro Uemura, Tatsuaki Sumiyoshi, Ryuta Shintakuya, Kenta Baba, Takumi Harada, Yasutaka Ishii, Shiro Oka, Yoshiaki Murakami, Shinya Takahashi   +9 more
wiley   +1 more source

Cancer nanomedicine in preoperative therapeutics: Nanotechnology-enabled neoadjuvant chemotherapy, radiotherapy, immunotherapy, and phototherapy

Bioactive Materials, 2023
Surgical resection remains a mainstay in the treatment of malignant solid tumors. However, the use of neoadjuvant treatments, including chemotherapy, radiotherapy, phototherapy, and immunotherapy, either alone or in combination, as a preoperative ...
Xiaogang Qu, Dong Zhou, Jianpu Lu, Duotian Qin, Jun Zhou, Hai-Jun Liu   +5 more
doaj  

Optimal duration of antimicrobial prophylaxis in patients undergoing distal pancreatectomy: A multicenter cohort study

Annals of Gastroenterological Surgery, EarlyView.
Prolonged administration of antimicrobial prophylaxis might not be effective to prevent surgical site infections after distal pancreatectomy compared to intraoperative or up to 24‐h administration. Abstract Background Antimicrobial prophylaxis is routinely administered in patients undergoing distal pancreatectomy, with cephalosporins being the most ...
Kenjiro Okada, Kenichiro Uemura, Sohei Satoi, Tsutomu Fujii, Manabu Kawai, So Yamaki, Toru Watanabe, Hideki Motobayashi, Shinya Takahashi   +8 more
wiley   +1 more source

Neoadjuvant therapy for esophageal cancer

World Journal of Gastrointestinal Oncology, 2014
Esophageal cancer is increasing in incidence more than any other visceral malignancy in North America. Adenocarcinoma has become the most common cell type. Surgery remains the primary treatment modality for locoregional disease. Overall survival with surgery alone has been dismal, with metastatic disease the primary mode of treatment failure after an ...
James P. Neifeld, Rachit D. Shah, Anthony D. Cassano   +2 more
openaire   +3 more sources

Validity of upfront surgery for patients with unsuspected lymph node metastasis in esophageal cancer: a propensity scoring matching study

Journal of Cardiothoracic Surgery, 2018
Background Although neoadjuvant therapy followed by esophagectomy is well-established as being superior to upfront esophagectomy when locoregional lymph node (LN) metastasis is present in esophageal cancer, upfront esophagectomy without neoadjuvant ...
Jae Kil Park, Jae Jun Kim, Seok Whan Moon, Deog Gon Cho   +3 more
doaj   +1 more source

Total Neoadjuvant Therapy With FOLFIRINOX in Combination With Losartan Followed by Chemoradiotherapy for Locally Advanced Pancreatic Cancer: A Phase 2 Clinical Trial.

JAMA Oncology, 2019
Importance Patients with locally advanced pancreatic cancer have historically poor outcomes. Evaluation of a total neoadjuvant approach is warranted. Objective To evaluate the margin-negative (R0) resection rate of neoadjuvant FOLFIRINOX (fluorouracil,
Janet E. Murphy, J. Wo, D. Ryan, Jeffrey W. Clark, Wenqing Jiang, B. Yeap, L. Drapek, L. Ly, Christian V. Baglini, L. Blaszkowsky, C. Ferrone, A. Parikh, C. Weekes, R. Nipp, E. Kwak, Jill N. Allen, R. Corcoran, D. Ting, J. Faris, A. Zhu, L. Goyal, D. Berger, M. Qadan, K. Lillemoe, Nilesh P. Talele, R. Jain, T. Delaney, D. Duda, Y. Boucher, C. F. Fernandez-Del Castillo, T. Hong   +30 more
semanticscholar   +1 more source