Results 141 to 150 of about 4,626,170 (385)

Long‐Term Survival of Two Versus Three Courses of Preoperative Cisplatin and Fluorouracil Plus Docetaxel for Locally Advanced Esophageal Cancer: A Multicenter Randomized Phase II Trial

Annals of Gastroenterological Surgery, EarlyView.
This multi‐institutional, randomized, phase II trial aimed to investigate the long‐term survival outcomes of two versus three courses of DCF for locally advanced esophageal squamous cell carcinoma (ESCC). The 5‐year overall survival and progression‐free survival rates for the three and two course groups were 70.7% vs. 63.8% (hazard ratio (HR) = 0.91, p 
Takahito Sugase, Hiroshi Miyata, Takashi Kanemura, Norihiro Matsuura, Tomoki Makino, Makoto Yamasaki, Koji Tanaka, Kotaro Yamashita, Kota Momose, Osamu Shiraishi, Keijiro Sugimura, Masaaki Motoori, Kazumasa Fujitani, Atsushi Takeno, Motohiro Hirao, Yutaka Kimura, Taroh Satoh, Masahiko Yano, Yuichiro Doki, Takushi Yasuda   +19 more
wiley   +1 more source

Inflammatory fibroblasts mediate resistance to neoadjuvant therapy in rectal cancer.

Cancer Cell, 2022
Adele M. Nicolas, M. Pesic, Esther Engel, Paul K Ziegler, M. Diefenhardt, Kilian B. Kennel, F. Buettner, Claire Conche, V. Petrocelli, Eiman Elwakeel, A. Weigert, A. Zinoveva, Maximilian Fleischmann, Björn Häupl, Cem Karakütük, H. Bohnenberger, Mohammed H. Mosa, L. Kaderali, J. Gaedcke, M. Ghadimi, F. Rödel, M. C. Arkan, T. Oellerich, C. Rödel, E. Fokas, F. Greten   +25 more
semanticscholar   +1 more source

Results of neoadjuvant chemotherapy and radiation therapy in the breast-conserving treatment of 250 patients with all stages of infiltrative breast cancer [PDF]

, 1990
C Jacquillat, Marise Weil, F Baillet, Christian Borel, G Auclerc, M. A. De Maublanc, Martin Housset, Geneviève Forget, L Thill, Claude Soubrane, David Khayat   +10 more
openalex   +1 more source

Surgical Procedure of Lateral Lymph Node Dissection for Advanced Lower Rectal Cancer

Annals of Gastroenterological Surgery, EarlyView.
Lateral lymph node dissection (LLND) is an effective surgical approach for lower rectal cancer. This paper outlines key points from the Japan Society of Gastroenterological Surgery consensus meeting, including standardized LLND techniques and procedural highlights.
Mamoru Uemura, Jun Watanabe, Akio Shiomi, Takashi Akiyoshi, George J. Chang, Yukihide Kanemitsu, Ichiro Takemasa, Yoshiharu Sakai, Masahiko Watanabe, Itaru Endo   +9 more
wiley   +1 more source

Personalized response-directed surgery and adjuvant therapy after neoadjuvant ipilimumab and nivolumab in high-risk stage III melanoma: the PRADO trial

Nature Network Boston, 2022
I. Reijers, A. Menzies, A. V. Van Akkooi, J. Versluis, N. V. D. van den Heuvel, R. Saw, T. Pennington, E. Kapiteijn, A. V. D. van der Veldt, K. Suijkerbuijk, G. Hospers, E. Rozeman, W. Klop, W. V. van Houdt, K. Sikorska, J. A. van der Hage, D. Grünhagen, M. Wouters, A. Witkamp, C. Zuur, J. Lijnsvelt, A. Torres Acosta, L. Grijpink-Ongering, Maria Gonzalez, K. Jóźwiak, C. Bierman, K. Shannon, S. Ch’ng, A. Colebatch, A. Spillane, J. Haanen, R. Rawson, B. A. Van de Wiel, L. V. van de Poll-Franse, R. Scolyer, A. Boekhout, G. Long, C. Blank   +37 more
semanticscholar   +1 more source

Improved Axillary Evaluation Following Neoadjuvant Therapy for Patients With Node-Positive Breast Cancer Using Selective Evaluation of Clipped Nodes: Implementation of Targeted Axillary Dissection.

Journal of Clinical Oncology, 2016
PURPOSE Placing clips in nodes with biopsy-confirmed metastasis before initiating neoadjuvant therapy allows for evaluation of response in breast cancer.
A. Caudle, W. Yang, S. Krishnamurthy, E. Mittendorf, Dalliah M. Black, M. Gilcrease, I. Bedrosian, B. Hobbs, S. DeSnyder, R. Hwang, B. Adrada, S. Shaitelman, M. Chávez-MacGregor, Benjamin D. Smith, R. Candelaria, G. Babiera, B. Dogan, L. Santiago, K. Hunt, H. Kuerer   +19 more
semanticscholar   +1 more source

Role for targeted resection in the multidisciplinary treatment of metastatic gastrointestinal stromal tumor [PDF]

, 2019
The management of advanced gastrointestinal stromal tumors (GISTs) has evolved in the modern era due to the discovery of c-kit mutations and the development of tyrosine kinase inhibitors (TKIs).
Feizpour, Cyrus, Kays, Joshua K., Kim, Bradford J., Koniaris, Leonidas G., Milgrom, Daniel P.   +4 more
core   +1 more source

Essential Updates 2023/2024: Recent Advances of Multimodal Approach in Patients for Gastric Cancer

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Gastric cancer remains a major global health burden, especially in East Asia. Recent years have brought significant advances in multimodal management, including surgery, perioperative chemotherapy, immunotherapy, and supportive care. This review summarizes key updates from 2023 to 2024, focusing on surgical innovations, perioperative systemic ...
Katsutoshi Shoda, Yoshihiko Kawaguchi, Suguru Maruyama, Daisuke Ichikawa   +3 more
wiley   +1 more source

Personalized circulating tumor DNA analysis to detect residual disease after neoadjuvant therapy in breast cancer

Science Translational Medicine, 2019
A robust personalized ctDNA test, TARDIS, achieves high accuracy for residual disease after completion of neoadjuvant therapy. Early detection, no time travel needed Analysis of tumor DNA shed into a patient’s circulation can provide a noninvasive means ...
B. R. McDonald, T. Contente-Cuomo, S. Sammut, Ahuva Odenheimer-Bergman, Brenda J Ernst, N. Perdigones, S. Chin, M. Farooq, Rosa Mejia, P. Cronin, K. Anderson, H. Kosiorek, D. Northfelt, A. McCullough, B. Patel, J. Weitzel, T. Slavin, C. Caldas, B. Pockaj, M. Murtaza   +19 more
semanticscholar   +1 more source

Significance of Intraoperative Lavage Cytology in Perihilar Cholangiocarcinoma

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Perihilar cholangiocarcinoma (PHC) has a poor prognosis, with frequent early metastatic recurrence after curative resection. Peritoneal metastasis (PM) is particularly difficult to diagnose and predict. While intraoperative lavage cytology (CY) is a standard method to detect PM, its utility remains unclear in PHC.
Kentaro Miyake, Ryusei Matsuyama, Yusuke Nakazaki, Kota Sahara, Tomoaki Takahashi, Yutaro Kikuchi, Yasuhiro Yabushita, Yu Sawada, Yuki Homma, Itaru Endo   +9 more
wiley   +1 more source