Results 141 to 150 of about 4,593,278 (410)

TopoTxR: A topology-guided deep convolutional network for breast parenchyma learning on DCE-MRIs [PDF]

open access: yesVolume 99, 2025, 103373
Characterization of breast parenchyma in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is a challenging task owing to the complexity of underlying tissue structures. Existing quantitative approaches, like radiomics and deep learning models, lack explicit quantification of intricate and subtle parenchymal structures, including ...
arxiv   +1 more source

Tumor microenvironment immune response in pancreatic ductal adenocarcinoma patients treated with neoadjuvant therapy.

open access: yesJournal of the National Cancer Institute, 2020
BACKGROUND Neoadjuvant FOLFIRINOX and chemoradiation have been utilized to downstage borderline and locally advanced pancreatic ductal adenocarcinoma (PDAC).
T. Michelakos   +22 more
semanticscholar   +1 more source

Neoadjuvant Trastuzumab Emtansine and Pertuzumab in Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer: Three-Year Outcomes From the Phase III KRISTINE Study. [PDF]

open access: yes, 2019
PurposeThe KRISTINE study compared neoadjuvant trastuzumab emtansine plus pertuzumab (T-DM1+P) with docetaxel, carboplatin, trastuzumab plus P (TCH+P) for the treatment human epidermal growth factor receptor 2-positive stage II to III breast cancer.
Afenjar, Karen   +20 more
core  

Impact of primary tumor clinicopathological factors on prognosis after hepatic resection for rectal liver metastases

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This retrospective study evaluates the prognostic factors in patients undergoing curative hepatic resection for rectal cancer liver metastases. It identifies lateral lymph node metastasis and perineural invasion as significant prognostic factors. Moreover, patients with these factors required nonsurgical treatment in the early postoperative period ...
Tomofumi Uotani   +9 more
wiley   +1 more source

Cancer treatment scheduling and dynamic heterogeneity in social dilemmas of tumour acidity and vasculature [PDF]

open access: yesarXiv, 2016
Background: Tumours are diverse ecosystems with persistent heterogeneity in various cancer hallmarks like self-sufficiency of growth factor production for angiogenesis and reprogramming of energy-metabolism for aerobic glycolysis. This heterogeneity has consequences for diagnosis, treatment, and disease progression.
arxiv  

Survival in Locally Advanced Pancreatic Cancer After Neoadjuvant Therapy and Surgical Resection.

open access: yesAnnals of Surgery, 2019
OBJECTIVE The aim of the study was to identify the survival of patients with locally advanced pancreatic cancer (LAPC) and assess the effect of surgical resection after neoadjuvant therapy on patient outcomes.
G. Gemenetzis   +13 more
semanticscholar   +1 more source

Perioperative outcomes of esophagectomy after doublet versus docetaxel‐based triplet neoadjuvant chemotherapy in older patients: A nationwide inpatient database study in Japan

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
In this nationwide inpatient database study of 5229 patients aged 70–79 years who underwent esophagectomy for cancer after neoadjuvant chemotherapy, overlap propensity score weighting analysis showed that neoadjuvant docetaxel‐based triplet regimen (docetaxel, cisplatin, and 5‐fluorouracil) was not associated with a higher incidence of perioperative ...
Yuki Hirano   +11 more
wiley   +1 more source

Long‐Term Outcomes of Neoadjuvant Therapy Versus Upfront Surgery for Resectable Pancreatic Ductal Adenocarcinoma

open access: yesCancer Medicine
Introduction This study aimed to compare the long‐term effects of neoadjuvant therapy and upfront surgery on overall survival (OS) and progression‐free survival (PFS) in patients with resectable pancreatic ductal adenocarcinoma (PDAC).
Kyung In Shin   +14 more
doaj   +1 more source

Factors Predicting Response, Perioperative Outcomes, and Survival Following Total Neoadjuvant Therapy for Borderline/Locally Advanced Pancreatic Cancer.

open access: yesAnnals of Surgery, 2019
MINI: Total neoadjuvant therapy, or systemic induction chemotherapy followed by chemoradiation, is an optimal preoperative sequencing strategy for patients with borderline resectable or locally advanced pancreatic adenocarcinoma.
M. Truty   +13 more
semanticscholar   +1 more source

Institutional learning curve and factors of prolonged operation time of robotic distal pancreatectomy: An analysis of an initial 117 cases

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This study verified the effective implementation of robotic distal pancreatectomy as the standard approach in our strategic robotic surgical oncology program. Although an institutional learning curve was observed, the robotic surgery program successfully expanded the number of primary operating surgeons while maintaining stable short‐term outcomes ...
Yuki Hirata   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy