Results 271 to 280 of about 4,732,777 (361)

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Progress in the Application of Single-Cell Sequencing in Neoadjuvant Therapy for Esophageal Cancer. [PDF]

Cureus
Houyi S, Zhiqiang S, Jianlin W, Xinchu N, Judong L.   +4 more
europepmc   +1 more source

The 5‐Methylcytosine RNA Modification in Hepatitis B Virus‐Negative Hepatocellular Carcinoma: Insights From Long‐Read Nanopore Sequencing

Molecular Carcinogenesis, EarlyView.
ABSTRACT 5‐Methylcytosine (m5C) RNA modification contributes to tumor initiation and progression. However, its transcriptome‐wide distribution patterns and biological implications in hepatitis B virus (HBV)‐negative hepatocellular carcinoma (HCC) remain poorly understood.
Tianhan Sun, Liying Zhou, XiaoQing Li, Ryan Xiao, Gaoyuan Sun, Lili Zhang, Yifei Li, Wei Huang, Yayu Li, Lu Kuai, Xuanmei Luo, Hongyuan Cui, Meng Chen   +12 more
wiley   +1 more source

Predicting Tumor Regrowth in Patients Undergoing Non-Operative Management after Total Neoadjuvant Therapy. [PDF]

J Gastrointest Cancer
Erozkan K, Simon E, Steinhagen E, Henke L, Costedio M, Selfridge JE, Viswanath SE, Charles R.   +7 more
europepmc   +1 more source

Single‐Cell Transcriptomic Analysis Reveals Epithelial‐Mesenchymal Transition and Key Gene AGRN as a Universal Programme in Gastrointestinal Tumours by an Artificial Intelligence‐Derived Prognostic Index

Med Research, EarlyView.
Intra‐tumour heterogeneity is present in gastrointestinal tumours at the single‐cell level. Cell cycling, EMT, MYC and TNF‐α are the four main consensus meta‐programs in gastrointestinal tumours. Then, a prognostic model based on intratumoral heterogeneity was constructed using an artificial intelligence‐derived prognostic index.
Zhizhan Ni, Pengyuan Zhu, Liming Liu, Haiyang Wang, Jinzhe Zhou, Xianqing Wang, Song Wang, Liangchen Zhu, Songze Zhang, Yongxin Zhou, Bujun Ge, Qi Huang, Chenshen Huang   +12 more
wiley   +1 more source

Neoadjuvant Therapy in Pancreatic Ductal Adenocarcinoma: Aligning Guideline Recommendations with Real-World Evidence. [PDF]

Cancers (Basel)
Cammarata R, Catamerò A, La Vaccara V, Coppola R, Caputo D.   +4 more
europepmc   +1 more source

Advances and Prospects of Stereotactic Radiosurgery and Stereotactic Ablative Body Radiotherapy: Evolving Paradigms in Precision Oncology

Med Research, EarlyView.
The graphical abstract outlines the progressive development and impact of stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT). Technological Evolution illustrates the transition from brachytherapy with single‐dose, LDR/HDR schedules to fractionated radiotherapy, three‐dimensional conformal radiotherapy (3DCRT) and Gamma Knife ...
Jing Zhang, Wenhao Xu, Weiqing Lu, Yingxuan Lin, Luoxi He, Zonglin Lv, Yiliyaer Nuerrula, Zouting, Zhen Zhang, Hailiang Zhang, Xuejun Ma   +10 more
wiley   +1 more source

Neoadjuvant therapy for pMMR/MSS locally advanced rectal cancer in the immunotherapy era: current landscape and future perspectives. [PDF]

Front Oncol
Farooq B, Li X, Xiao S, Liu X.
europepmc   +1 more source

Comparative Efficacy of Metabolic/Bariatric Surgery Versus GLP‐1 Receptor Agonists: A Network Meta‐Analysis of Randomized Controlled Trials

Obesity, EarlyView.
ABSTRACT Objective This study compared the efficacy of metabolic/bariatric surgery (MBS) and GLP‐1 receptor agonists (GLP‐1 RAs), including dual GLP‐1/GIP analogues, for weight and metabolic outcomes in adults with obesity. Methods A network meta‐analysis of randomized controlled trials compared MBS or GLP‐1 RAs versus lifestyle intervention in adults ...
Lucas Sabatella, Patricia M. Ortega, Víctor Valentí Azcárate, Fernando Rotellar Sastre, Adriana Uriz Pagola, Ahmed Ahmed, Sanjay Purkayastha, Carlota Tuero Ojanguren, Nuria Blanco Asensio, Manuel F. Landecho   +9 more
wiley   +1 more source

Pseudoprogression of Non-Small Cell Lung Cancer Following Neoadjuvant Therapy: A Case Report. [PDF]

Cureus
Ramadan K, Benaissa M, Shackcloth M.
europepmc   +1 more source