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Development of isolated neocortex
Experientia, 1973La migration des neuroblastes et la croissance des aires dendritiques de base des neurones pyramidaux font ici l'objet d'une etude portant sur les regions IV et Vb du neocortex cerebral isole de rats de souche Wistar. La migration des neuroblastes s'effectuait normalement et aboutissait au dispositif habituel ordonne en 6 regions.
M, Berry, T, Hollingworth
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Neuronal Domains in Developing Neocortex
Science, 1992The mammalian neocortex consists of a mosaic of columnar units whose development is poorly understood. Optical recordings of brain slices labeled with the fluorescent calcium indicator fura-2 revealed that the neonatal rat cortex was partitioned into distinct domains of spontaneously coactive neurons.
R, Yuste, A, Peinado, L C, Katz
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Hypoxia-Induced Dysfunction in Developing Rat Neocortex
Journal of Neurophysiology, 1997Luhmann, Heiko J. and Thomas Kral. Hypoxia-induced dysfunction in developing rat neocortex. J. Neurophysiol. 78: 1212–1221, 1997. Neocortical slices from young [postnatal day (P) 5–8], juvenile (P14–18), and adult (>P28) rats were exposed to long periods of hypoxia.
H J, Luhmann, T, Kral
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GABAergic Transcallosal Neurons in Developing Rat Neocortex
European Journal of Neuroscience, 1997AbstractIn the mature cerebral cortex the interhemispheric connections across the corpus callosum appear to be essentially completely excitatory on the basis of both immunocytochemical and electrophysiological studies. During late embryonic development, however, immunocytochemical staining reveals numerous GABA‐positive fibres in the callosum, which ...
F, Kimura, R W, Baughman
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Development of the noradrenergic innervation of neocortex
Brain Research, 1979The development of the noradrenaline (NA)-neuron innervation of rat neocortex was studied by fluorescence histochemistry, high affinity uptake of [3H-]NA, and biochemical assay of regional NA content. Fluorescence histochemistry indicates that NA axons enter areas of developing neocortex prenatally and the innervation matures rapidly during early ...
P, Levitt, R Y, Moore
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Gap junctions in developing neocortex: a review
Brain Research Reviews, 2004Several independent lines of evidence indicate that gap junctional coupling is widespread and functionally important in early cortical development. The extensive expression of many connexins, the clusters of coupled neuroblasts or neurons revealed by tracer injections or the functional coactivation of neurons shown by calcium imaging can be seen as ...
Rafael J, Montoro, Rafael, Yuste
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DYX1C1 functions in neuronal migration in developing neocortex
Neuroscience, 2006Rodent homologues of two candidate dyslexia susceptibility genes, Kiaa0319 and Dcdc2, have been shown to play roles in neuronal migration in developing cerebral neocortex. This functional role is consistent with the hypothesis that dyslexia susceptibility is increased by interference with normal neural development. In this study we report that in utero
Y, Wang +9 more
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Proliferation and apoptosis in the developing human neocortex
The Anatomical Record, 2002AbstractThe cell kinetics of the developing central nervous system (CNS) is determined by both proliferation and apoptosis. In the human neocortex at week 6 of gestation, proliferation is confined to the ventricular zone, where mitotic figures and nuclear immunoreactivity for proliferating cell nuclear antigen (PCNA) are detectable.
Wood Yee, Chan +3 more
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