Results 91 to 100 of about 178,038 (303)

Cosmic ray neon, Wolf-Rayet stars, and the superbubble origin of galactic cosmic rays [PDF]

, 2005
The abundances of neon isotopes in the galactic cosmic rays (GCRs) are reported using data from the Cosmic Ray Isotope Spectrometer (CRIS) aboard the Advanced Composition Explorer (ACE). We compare our ACE-CRIS data for neon and refractory isotope ratios,
A. C. Cummings, Audouze J., Connell J. J., Connell J. J., E.C. Stone, Engelmann J. J., Epstein R. I., G. Meynet, Geiss J., Huss G. R., J. S. George, Kafatos M., L. M. Scott, Leske R. A., Leske R. A., M. Arnould, M. E. Wiedenbeck, M. H. Israel, Maeder A., Maehl R., Meylan G., Meynet G., Meynet G., Niedzielski A., Nugis T., R. A. Leske, R. A. Mewaldt, S. Goriely, Schaller G., Soutoul A., Stone E. C., Streitmatter R. E., T. T. von Rosenvinge, van der Hucht K. A., W. R. Binns, Wiedenbeck M. E., Wiedenbeck M. E., Wieler R., Willis A. J.   +38 more
core   +2 more sources

Hierarchically Engineered Multi‐Enzyme Nanoreactors for in vitro Drug Biosynthesis and Pathway Transplantation Into Cells

Advanced Materials, EarlyView.
A hierarchically structured metal–organic framework (eMIL) is shown to host the complete six‐enzyme biosynthesis pathway for the anti‐cancer pigment violacein, reshaping reaction dynamics and multiplying in vitro yields. eMIL nanoreactors deliver this reconstituted bacterial multi‐protein system into mammalian cells, where cell‐derived substrates and ...
Ainur Sharip, Somayah S. Qutub, Manar M. Farooqui, Walaa Baslyman, Nida Khalfay, Lukman O. Alimi, Patricia Lopez Sanchez, Lingyun Zhao, Milena Chernyshevskaia, Giovanni Colombo, Niveen M. Khashab, Stefan T. Arold, Raik Grünberg   +12 more
wiley   +1 more source

Microfluidic Engineering of Chitosan‐Coated Nanoemulsions for Controlled Release and Stability in Space Pharmaceutics

Advanced Materials Technologies, EarlyView.
Microfluidic engineering enables the fabrication of chitosan‐coated, melatonin‐loaded nanoemulsions with controlled release and enhanced physicochemical stability for space pharmaceutics. Interfacial biopolymer coating modulates droplet behavior under accelerated thermal stress and simulated microgravity.
Modupe Adebowale, Nguyen Van Duc Long, Philip M Williams, Volker Hessel   +3 more
wiley   +1 more source

New Directions in Focused Ion Beam Induced Deposition for the Nanoprinting of Functional 3D Heterostructures

Advanced Materials Technologies, EarlyView.
Here, it is shown that focused ion beam induced deposition (FIBID) using helium and neon ions enables advanced high‐resolution 3D nanoprinting achieving precise multimaterial architectures and engineered internal voids. Thus, FIBID with finely focused noble gas ion species is presented as a unique platform for designing functional nanomaterials for ...
Frances Isabel Allen
wiley   +1 more source

Multimodal Haptic Perception Through Synergistic Nanocomposite Sensor Arrays

Advanced Materials Technologies, EarlyView.
Multi‐modal fingertip haptics are advanced through a bioinspired &vertical‐via' electronic skin architecture. A confined PDMS/MWCNT/NiNP nanocomposite, sitting at the percolation threshold, enables tactile, thermal, and magnetic sensing. A unique via‐density gradient and dedicated &Un‐Touch' reference nodes provide robust spatial resolution and signal ...
Amos Bardea, Fernando Patolsky
wiley   +1 more source

Cell Cycle Control of Nuclear Metabolism Couples Phosphatidylinositol Signaling to Histone Methylation

Advanced Science, EarlyView.
Nuclear metabolism oscillates during cell cycle progression. Quantitative chromatome proteomics and imaging reveal phase‐specific dynamics of PIP5K1A and nuclear PIP2, linking phosphatidylinositol metabolism to histone methylation. This work identifies nuclear lipid metabolism as a previously unrecognized regulatory axis coordinating chromatin ...
Antoni Gañez‐Zapater, Savvas Kourtis, Camilla Reiter Elbæk, Lorena Espinar, Carolina Toro‐Márquez, Albert Coll‐Manzano, Alfredo Smiriglia, Laura García‐López, Laura Wiegand, Maria Guirola, Frédéric Fontaine, Andrea Morandi, André C. Müller, Sara Sdelci   +13 more
wiley   +1 more source

Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors

Advanced Science, EarlyView.
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen, Scott R Walsh, Li Deng, Lan Chen, Yonghong Wan   +4 more
wiley   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Perception and appropriation of a web-based recovery narratives intervention: qualitative interview study

Frontiers in Digital Health
IntroductionMental health recovery narratives are widely available to the public, and can benefit people affected by mental health problems. The NEON Intervention is a novel web-based digital health intervention providing access to the NEON Collection of
Yasmin Ali, Stefan Rennick-Egglestone, Joy Llewellyn-Beardsley, Fiona Ng, Caroline Yeo, Caroline Yeo, Donna Franklin, Donna Franklin, Elvira Perez Vallejos, Elvira Perez Vallejos, Dror Ben-Zeev, Yasuhiro Kotera, Yasuhiro Kotera, Mike Slade, Mike Slade   +14 more
doaj   +1 more source

Does a Partial Rotator Cuff Tear Affect Pitching Ability? Results From an MRI Study

Orthopaedic Journal of Sports Medicine, 2019
Background: Numerous studies have examined changes in the athletic performance of baseball pitchers after rotator cuff surgery. However, only a few studies have evaluated changes in athletic performance caused by partial rotator cuff tears that are not ...
Jin-Young Park MD, PhD, Junhyun Kim MD, Jae-Hyung Lee MD, Kyung-Soo Oh MD, Seok Won Chung MD, Hyunjun Park   +5 more
doaj   +1 more source