Results 71 to 80 of about 23,878 (259)

The role of tree traits in explaining throughfall variability in US forests

Ecosphere
Throughfall, precipitation that passes through the plant canopy or drips from canopy surfaces, represents the dominant input of water to most forests and is extremely spatially and temporally variable.
Edward Ayres
doaj   +1 more source

Gut Microbiota, Immunity, and Metabolism in the Progression From Chronic Liver Disease to Hepatocellular Carcinoma

Advanced Science, EarlyView.
This review explains how chronic liver injury progresses toward hepatocellular carcinoma through interconnected changes in gut microbes, metabolism, immunity, fibrosis, and diet. It highlights microbial metabolites, bile‐acid signaling, immune dysfunction, and nutritional or microbiome‐based interventions as opportunities to identify risk earlier ...
Yi Hu, Caiyan Lin, Lijie Zhang, Xue Jiang, Huawen Li, Yangzhe Wu   +5 more
wiley   +1 more source

Localizable Fluorescent Metal Ion Indicators With Tunable Colors

Advanced Science, EarlyView.
A modular platform enables the generation of fluorescent metal ion indicators with tunable emission colors and precise subcellular localization. Conjugation to self‐labeling proteins yields bright, color‐tunable potassium probes that permit wash‐free live‐cell imaging, revealing dynamic potassium efflux in stimulated neurons.
Ming‐Ming Wang, De‐en Sun, Klara Gries, Kai Johnsson   +3 more
wiley   +1 more source

A High‐Throughput Live Imaging Platform to Investigate Circuit‐Dependent Regulation of Circadian Rhythms in Brain Tissue

Advanced Science, EarlyView.
Biological rhythms coordinate physiology, from genes to behavior. Study of circadian rhythms in brain tissue is constrained by limited throughput and spatial and temporal information quality. A new platform for high‐throughput, long‐term multiplexed fluorescent live imaging of circadian rhythms in brain slices is introduced.
Marco Ferrari, Natalie Ness, Julieta Acosta, Marco Brancaccio   +3 more
wiley   +1 more source

Integrated Single‐Cell and Spatial Analysis Reveals a Metabolic‐Immune Axis Driving Aortic Dissection

Advanced Science, EarlyView.
Single‐cell and spatial profiling of 110 human thoracic aortic samples reveals a stromal–immune circuit driving aortic dissection. An elastin‐rich fibroblast subset is depleted with age and markedly reduced in disease, weakening aortic wall integrity.
Jing Tao, Huanjie Yang, Jiahui Yong, Xueting Chen, Qiang Zhao, Xueli Wu, Lei Yan, Li Pang, Fan Luo, Mengjun Yu, Shanshan Pan, Deyang Li, Rouxi Chen, Juan Wang, Zhensheng Dong, Fan Yang, Yue Wang, Yang Chen, Hongjian Zheng, Zhimin Yang, Zijie Wang, Karsten Kristiansen, Hui Peng, Xiaodong Fang, Juan Shen, Yining Yang   +25 more
wiley   +1 more source

Perception and appropriation of a web-based recovery narratives intervention: qualitative interview study

Frontiers in Digital Health
IntroductionMental health recovery narratives are widely available to the public, and can benefit people affected by mental health problems. The NEON Intervention is a novel web-based digital health intervention providing access to the NEON Collection of
Yasmin Ali, Stefan Rennick-Egglestone, Joy Llewellyn-Beardsley, Fiona Ng, Caroline Yeo, Caroline Yeo, Donna Franklin, Donna Franklin, Elvira Perez Vallejos, Elvira Perez Vallejos, Dror Ben-Zeev, Yasuhiro Kotera, Yasuhiro Kotera, Mike Slade, Mike Slade   +14 more
doaj   +1 more source

Does a Partial Rotator Cuff Tear Affect Pitching Ability? Results From an MRI Study

Orthopaedic Journal of Sports Medicine, 2019
Background: Numerous studies have examined changes in the athletic performance of baseball pitchers after rotator cuff surgery. However, only a few studies have evaluated changes in athletic performance caused by partial rotator cuff tears that are not ...
Jin-Young Park MD, PhD, Junhyun Kim MD, Jae-Hyung Lee MD, Kyung-Soo Oh MD, Seok Won Chung MD, Hyunjun Park   +5 more
doaj   +1 more source

CK2α Deficiency Drives Myocardial Fibrosis via Desmin‐Induced Mitochondrial Dysfunction

Advanced Science, EarlyView.
CK2α preserves mitochondrial homeostasis by phosphorylating Desmin to recruit Cryab, ensuring proper filament assembly. CK2α deficiency disrupts this interaction, causing mitochondrial dysfunction, metabolic shifts, bioenergetic failure, and oxidative stress—ultimately establishing a pro‐fibrotic environment that drives cardiac fibrosis.
Canjie Ma, Jiali Jia, Juncong Lan, Jing Wang, Dan Rao, Lanlan Rao, Weibin Zhang, Dongpeng Wu, Jie Zhang, Gang Wang, Baohua Liu, Ying Ao, Zimei Wang   +12 more
wiley   +1 more source

Clinical and Radiologic Outcomes of the Bankart Repair Using Mason-Allen (BRUMA) Technique for Small Bony Bankart Lesions: An Objective, Performance Criteria-Referenced, Single-Surgeon Case Series

Orthopaedic Journal of Sports Medicine
Background: The optimal management of small bony Bankart lesions remains controversial. The Bankart repair using Mason-Allen (BRUMA) technique uses indirect fragment reduction through capsulolabral retensioning without direct fixation of the bony ...
Hyung Seo Jung MD, Hong-Keun Park MD, Kyung-Soo Oh MD, PhD, Jin-Young Park MD, PhD   +3 more
doaj   +1 more source

Master Regulator SMC1A, Stabilized by N6‐Methyladenosine Reader IGF2BP1, Promotes HCC Progression Through Facilitating Enhancer–Promoter Interaction of Nestin

Advanced Science, EarlyView.
IGF2BP1‐mediated m6A stabilization sustains SMC1A expression, enabling cohesin‐associated chromatin regulation of Nestin in hepatocellular carcinoma. This work reveals an epitranscriptomic‐chromatin‐cytoskeletal regulatory axis linked to malignant phenotypes and identifies SMC1A as a biologically relevant vulnerability in HCC.
Zhenxiang Peng, Diguang Wen, Lu Zeng, Lin Lv, Shengtao Liao, Wenguang Zhang, Zhechuan Mei, Chuanfei Li   +7 more
wiley   +1 more source