Results 131 to 140 of about 23,878 (259)

Nonviral Gold Nanoparticle‐Mediated Delivery of CRISPR‐Cas9 Ribonucleoprotein and Long DNA Transgenes Into Primary Blood Cells

Advanced NanoBiomed Research, EarlyView.
CRISPR/Cas9 has revolutionized the field of gene therapy, but delivery remains an outstanding issue. We propose a nonviral gold‐nanoparticle platform for co‐delivery of CRISPR/Cas9 ribonucleoprotein and long 2.1 kilobase dsDNA transgene constructs. This CRISPR‐AuNP is inexpensive to produce and mediate gene editing and DNA delivery in T cells and CD34+
Rachel A. Cunningham, Karthikeya S. V. Gottimukkala, Daniel D. Lane, Katrina Poljakov, Patricia Lipson, Mark R. Enstrom, Alessandro Rizzi, Aude G. Chapuis, Jennifer E. Adair   +8 more
wiley   +1 more source

Chloroplast-Thylakoid Organisation Is More Important than Carotenoid Accumulation for Optimum Photosynthetic Quantum Yield and Carbon Gain in Variegated <i>Epipremnum aureum</i>. [PDF]

Cells
Falcioni R, Antunes WC, Chicati ML, Demattê JAM, Nanni MR.   +4 more
europepmc   +1 more source

Separability of the Coupled-Cluster Excited State Equations: The Case of Excitonic Couplings. [PDF]

J Phys Chem A
Köhn A.
europepmc   +1 more source

Abundance-Occupancy Relationships are Informed by Species Temporal Occupancy. [PDF]

Ecol Evol
Holian LA, Ten Caten C, Dallas TA.
europepmc   +1 more source

Photobiomodulation Enhances Tendon Regeneration: A Systematic Review and Meta‐analysis of Preclinical Studies

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To evaluate the preclinical evidence supporting the efficacy of photobiomodulation therapies in tendon regeneration. Methods A comprehensive literature search was conducted in MEDLINE, ScienceDirect, and Google Scholar to identify in vivo animal studies evaluating photobiomodulation therapies for tendon healing.
Yose Waluyo, Diah Nurul Islami Muchsin, Muthiah Nur Afifah, Yaldi Rosadi, M. Salas Al Aldi   +4 more
wiley   +1 more source

Sporecasting Biogeography Across Scales: Continental Patterns and Local Constraints on Macrofungal Dispersal. [PDF]

Mol Ecol
Ratz AW, Arnold AE, Burrill HM, Caiafa MV, Conery J, Dawson HA, Delevich CA, Diez JM, Frey SD, Lodge DJ, Ronold EK, Roy BA, Smith ME, U'Ren J, Wilson AW, Loucks JJ, Wuest J, Willis CB, Kennedy PG.   +18 more
europepmc   +1 more source

Lower Extremity Sprains and Knee/Ankle Injury Predominate Among Pediatric Dancers

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To determine the most common body regions, diagnoses, and mechanisms of injury among pediatric dance‐related injuries in the United States. Methods A descriptive epidemiologic analysis of the National Electronic Injury Surveillance System from January 1, 2019 to December 31, 2023 identified emergency department presentations for primary dance ...
Katherine Koch, Philip M. Lee, Cameron Nishida, Sonya B. Levine, Kyle K. Obana, Jennifer M. Weiss, Jennifer King   +6 more
wiley   +1 more source

Soil microbiome prediction using traditional machine learning and deep learning models. [PDF]

Sci Rep
Aouabed Z, Therrien V, Bouaoune MA, Bakhtyari M, Hijri M, Makarenkov V.   +5 more
europepmc   +1 more source

A Multifaceted Interplay Among Hemophagocytosis, Interleukin‐18, and Type I Interferon Distinguishes Still Disease From Other Autoinflammatory Diseases

Arthritis &Rheumatology, EarlyView.
Objective The unknown pathophysiology and the lack of specific features for systemic juvenile idiopathic arthritis and adult‐onset Still disease (collectively known as Still disease; SD) delay diagnosis and appropriate treatment. The goal of this study was to identify features and mechanisms that distinguish SD from other systemic autoinflammatory ...
Yvonne M. Mueller, Charlotte Girard, Harmen J. G. van de Werken, Stefan J. Erkeland, Dwin G. B. Grashof, Laurie Vaillant, Renske J. H. den Dekker, Iris van Zuijen, Sharon Veenbergen, Fanny Coffin, Eric Bindels, Yvan Jamilloux, Katerina Laskari, Vassili Soumelis, Bruno Fautrel, Cem Gabay, Peter D. Katsikis   +16 more
wiley   +1 more source

Tracking the Complex Dynamics of Electron-Transfer-Mediated Decay in Real Space and Time. [PDF]

J Am Chem Soc
Trinter F, Hofierka J, Rist J, Kircher M, Weller M, Melzer N, Tsitsonis D, Geyer A, Kruse J, Kastirke G, Williams JB, Miteva T, Dörner R, Schöffler MS, Kunitski M, Sisourat N, Cederbaum LS, Jahnke T.   +17 more
europepmc   +1 more source