Results 81 to 90 of about 316,235 (202)

Integrative proteomic profiling of extracellular vesicle‐enriched preparations with machine learning identifies disease activity‐associated signatures linked to adverse pregnancy outcomes in systemic lupus erythematosus

VIEW, EarlyView.
Integrating cross‐cohort extracellular vesicle proteomics with machine learning identifies a simplified protein signature (AGT, FETUB, SPP2, and FCN3) for adverse pregnancy outcome risk stratification in systemic lupus erythematosus, enabling precise disease‐activity discrimination beyond routine clinical assessment.
Weiwei Shi, Xipei Huang, Wutao Chen, Wen Di, Lin Huang, You Wang   +5 more
wiley   +1 more source

Cholestasis beyond the Neonatal and Infancy Periods

, 2016
Cholestasis results from impairment in the excretion of bile, which may be due to mechanical obstruction of bile flow or impairment of excretion of bile components into the bile canaliculus.
Racha Khalaf(Johns Hopkins All Children’s Hospital, St. Petersburg, FL, United Stat); Claudia Phen(Johns Hopkins All Children’s Hospital, St. Petersburg, FL, United States); Sara Karjoo(Johns Hopkins All Children’s Hospital, St. Petersburg, FL, United States); Michael Wilsey(Johns Hopkins All Children’s Hospital, St. Petersburg, FL, United States)
core  

Infection by cytomegalovirus in patients with neonatal cholestasis Infecção por cytomegalovirus em pacientes com colestase neonatal

Arquivos de Gastroenterologia, 2002
Background - Neonatal cholestasis syndrome with an intra or extrahepatic origin has been associated to viral infections. The participation of the cytomegalovirus in the etiopathogenesis of neonatal hepatitis has been already known for some time, but only
Nara Léia Gelle de OLIVEIRA, Fernanda Rafful KANAWATY, Sandra Cecilia Botelho COSTA, Gabriel HESSEL   +3 more
doaj   +1 more source

Gestational diabetes in multifetal versus singleton pregnancies: A multicenter cohort study

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Gestational diabetes in multifetal pregnancies was associated with increased maternal morbidity but less adverse neonatal and long‐term offspring outcomes than in singleton pregnancies, suggesting that current diagnostic thresholds derived from singleton gestations may not fully reflect the unique metabolic and clinical characteristics of multifetal ...
Rinat Gabbay‐Benziv, Esther Maor‐Sagie, Amos Stern, Inna Bleicher, Simon Shenhav, Enav Yefet, Yifat Wiener, Michal Kovo, Maya Frank Wolf   +8 more
wiley   +1 more source

Developmental Osteopenia: An Explanation for Fractures in Young Infants

Acta Paediatrica, EarlyView.
ABSTRACT Aim The aim is to test whether a fraction of full‐term infants pass through a phase of postnatal fracture susceptibility and whether this physiological phase explains real‐world fracture age distributions in young infants. Methods Preterm infant data were used to establish fracture risk zones based on bone quality (using Speed of Sound, SOS ...
Chris Brook, Julie Mack, Waney Squier
wiley   +1 more source

Neonatal intrahepatic cholestasis caused by citrin deficiency in Korean infants [PDF]

, 2007
Citrin is a liver-type mitochondrial aspartate-glutamate carrier encoded by the SLC25A13 gene, and its deficiency causes adult-onset type II citrullinemia and neonatal intrahepatic cholestasis caused by citrin deficiency (NICCD).
Seo, Jeong Kee, Park, Sung Sup, Ko, Jae Sung, Song, Jung Han   +3 more
core   +1 more source

Neonatal cholestasis: recent insights

Egyptian Pediatric Association Gazette, 2019
Background Neonatal physiological jaundice is a common benign condition that rarely extends behind the second week of life; however, it may interfere with the diagnosis of a pathological condition termed neonatal cholestasis (NC).
Ramy Mohamed Ghazy, Mohamed Ahmed Khedr
doaj   +1 more source

Postnatally Acquired Cytomegalovirus Infection in Extremely Premature Infants: A Prospective Observational Cohort Study

Acta Paediatrica, EarlyView.
ABSTRACT Aim Postnatally acquired cytomegalovirus (pCMV) infection may cause severe disease in extremely preterm infants, but its clinical significance remains uncertain. We investigated the incidence, timing, disease burden, and diagnostic performance of saliva screening. Method In this prospective cohort study, infants born at < 28 weeks of gestation
Sara Krøis Holm, Lise Aunsholt, Porntiva Poorisirak, Alex Christian Yde Nielsen, Rune Micha Pedersen, Bo Mølholm Hansen, Anne Mette Plomgaard, Karina Kwi Im Jordan, Hristo Stanchev, Maren Rytter, Tatjana Zaharov, Sven Bonato, Kia Schultz Dungu, Anja Poulsen, Susanne Søndergaard Kappel, Ulrikka Nygaard, Stine Lund   +16 more
wiley   +1 more source

Prognostic value of biochemical liver parameters in neonatal sepsis-associated cholestasis

, 2013
Aim:s The aim of the study was to evaluate the significance of total bilirubin, aspartate transaminase (AST), alanine transaminase and gamma-glutamyltransferase (GGT) for predicting outcome in sepsis-associated cholestasis.
Cleghorn, Geoffrey J., Oswari, Hanifah, Cleghorn, Geoffrey, Rohsiswatmo, Rinawati, Widjaja, Ruth Karisma   +4 more
core   +1 more source

Preventive Effect of Bifidobacterium Supplementation on Neonatal Cholestasis in Preterm Neonates with Very Low Birth Weight

Gastroenterology Research and Practice, 2020
Background. Cholestasis is a common but serious clinical condition in preterm neonates. The current management for preterm neonatal cholestasis has limitations.
Gaohong Wu, Xiaoqian Chen, Ningxun Cui, Yunxia He, Jiaying Fan, Dongya Yan, Xueping Zhu, Xiaoli Zhu   +7 more
doaj   +1 more source