A Framework for Emergency Department–Integrated Hepatitis C Test‐and‐Treat in the United States
ABSTRACT Despite the availability of curative, direct‐acting antiviral therapy, hepatitis C virus elimination remains incomplete. Losses across the care cascade continue to limit impact, from initial diagnosis to sustained virologic response. Fewer than 1/3 of individuals ultimately achieve cure. These gaps reflect a delivery system that does not align
Saeed S. Graham
wiley +1 more source
Single-Cell RNA Sequencing in Incontinentia Pigmenti With Neonatal Encephalopathy Reveals Broad Immune Activation Moderated by Steroids. [PDF]
Mohammad SS +8 more
europepmc +1 more source
Deciphering the Impact of RAC1‐SPTAN1 in ARPKD Cystogenesis Using Multifaceted Models
Distal/connecting tubules expressing SLC8A1 have been suggested as a potential origin of ARPKD cysts. SPTAN1 has been identified as a key molecule in ARPKD cyst formation. Restoring SPTAN1 in PKHD1−/− organoids reduced cyst formation, normalized calcium levels, and decreased RAC1/c‐FOS expression, highlighting SPTAN1's role in ARPKD and the potential ...
Shohei Kuraoka +9 more
wiley +1 more source
Clinician Stakeholder Experience With Telemedicine Consults to Assess Neonatal Encephalopathy in a Rural State. [PDF]
Seften LM +3 more
europepmc +1 more source
Cooling down for going up: Could selective ‘brain chilling’ mitigate high‐altitude illness?
Experimental Physiology, EarlyView.
Adnan Haq, Damian M. Bailey
wiley +1 more source
Inhalation of Isopropyl Alcohol Leading to Acute Severe Toxicity: A Case Report
ABSTRACT This case represents the first reported instance of adult isopropyl alcohol inhalation intoxication with a rapid onset (2 h) and initially negative serum and urine ketones. It highlights that early isopropyl alcohol intoxication may not exhibit the typical clinical features, such as respiratory depression, altered mental status, and positive ...
Ben Thiravetyan +7 more
wiley +1 more source
Cooling and physiology during parent cuddling infants with neonatal encephalopathy in usual care: CoolCuddle-2 study. [PDF]
Chakkarapani E +5 more
europepmc +1 more source
Partial microglial depletion indirectly promoted the activity of the STAT3 signaling pathway in neural cells and increased the proliferation and/or differentiation of NSCs in areas of infarction to exert neuroprotective effects via the paracrine effects of NSCs and immature neurons in HIE.
Ao Ding +10 more
wiley +1 more source
A Comparison of Automatically Extracted Quantitative EEG Features for Seizure Risk Stratification in Neonatal Encephalopathy. [PDF]
Keene JC +9 more
europepmc +1 more source
The impact of metal cup size on neonatal and maternal morbidity in vacuum‐assisted deliveries
Abstract Objective To evaluate whether metal cup size influences maternal and neonatal morbidity in vacuum‐assisted deliveries (VAD). Materials and Methods Retrospective cohort at a single tertiary center (2011–2022) comparing 60‐mm versus 50‐mm Malmström cups. A 1:1 matched cohort analysis balanced maternal and obstetric variables.
Matan Anteby +6 more
wiley +1 more source

