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Consensus definition and diagnostic criteria for neonatal encephalopathy-study protocol for a real-time modified delphi study. [PDF]
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Neonatal Epileptic Encephalopathies
Seminars in Pediatric Neurology, 2021The majority of neonatal seizures are related to common diagnoses, including hypoxic-ischemic encephalopathy and intraventricular hemorrhage. While relatively uncommon, neonatal epileptic encephalopathies represent an important group of neonatal seizure disorders that require immediate diagnosis and intervention. In this review, we provide a summary of
Samiya Fatima, Ahmad +2 more
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Neonatal Encephalopathy: Beyond Hypoxic-Ischemic Encephalopathy
NeoReviews, 2021Neonatal encephalopathy is a clinical syndrome of neurologic dysfunction that encompasses a broad spectrum of symptoms and severity, from mild irritability and feeding difficulties to coma and seizures. It is vital for providers to understand that the term “neonatal encephalopathy” is simply a description of the neonate’s neurologic status that is ...
Jeffrey B, Russ +2 more
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Neonatal endotoxin encephalopathy
Annals of Neurology, 1977AbstractTelencephalic white matter of the neonatal kitten frequently contained diffuse astrogliosis or focal necrosis (sometimes including the thalamus and the caudate) following a single intraperitoneal injection of Escherichia coli lipopolysaccharide. No evidence for a disseminated intravascular coagulopathy was found.
F H, Gilles, D R, Averill, C S, Kerr
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Neuroimaging of neonatal encephalopathies
Journal of Neuroradiology, 2007Neonatal brain disorders consist of a wide chapter including brain malformations, hypoxic-ischemic encephalopathy (HIE), intracranial infections, perinatal trauma and metabolic encephalopathy. We will focus here on HIE, intracranial infections (especially materno-fetal infection with or without prolonged and/or premature rupture of membranes) and ...
Girard, Nicolas +7 more
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MRI of Neonatal Encephalopathy
Clinical Radiology, 2003We present the magnetic resonance imaging (MRI) findings in neonatal encephalopathy, including hypoxic-ischaemic encephalopathy, perinatal/neonatal stroke, metabolic encephalopathy from inborn errors of metabolism, congenital central nervous system infections and birth trauma.
Lam, BCC +5 more
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Epidemiology of neonatal encephalopathy and hypoxic–ischaemic encephalopathy
Neonatal encephalopathy (NE) is the clinical manifestation of disordered neonatal brain function. Lack of universal agreed definitions of NE and the sub-group with hypoxic-ischaemia (HIE) makes the estimation of incidence and the identification of risk factors problematic. NE incidence is estimated as 3.0 per 1000 live births (95%CI 2.7 to 3.3) and for
Jennifer J Kurinczuk +1 more
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Placental contribution to neonatal encephalopathy
Seminars in Fetal and Neonatal Medicine, 2021Placental assessment, although currently underused, can inform our understanding of the etiology and timing of Neonatal Encephalopathy (NE). We review our current understanding of the links between placental dysfunction and NE and how this information may inform clinical decisions, now and in the future, emphasizing the four major placental lesions ...
A A, Penn +6 more
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Neonatal encephalopathy and hypoxic–ischemic encephalopathy
2019Acute hypoxic-ischemic encephalopathy around the time of birth remains a major cause of death and life-long disability. The key insight that led to the modern revival of studies of neuroprotection was that, after profound asphyxia, many brain cells show initial recovery from the insult during a short "latent" phase, typically lasting approximately 6h ...
Gunn, A, Thoresen, Marianne
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Neonatal encephalopathy: Etiologies other than hypoxic-ischemic encephalopathy
Seminars in Fetal and Neonatal Medicine, 2021Neonatal encephalopathy (NE) describes the clinical syndrome of a newborn with abnormal brain function that may result from a variety of etiologies. HIE should be distinguished from neonatal encephalopathy due to other causes using data gathered from the history, physical and neurological exam, and further investigations.
A G, Sandoval Karamian +7 more
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