Impact of Monoclonal Antibody Aggregates on Effector Function Characterization. [PDF]
Antibodies (Basel)Walton WJ +5 more
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Fast-acting treatment of myasthenic crisis with efgartigimod from the perspective of the neonatal intensive care unit. [PDF]
BMC NeurolShi F +9 more
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Clinical efficacy of efgartigimod combined with intravenous methylprednisolone in the acute phase of neuromyelitis optica spectrum disorders. [PDF]
Orphanet J Rare DisYang W, Chen P, Guo J, Feng H, Huang X.
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Influence of Distinct Maternal Cytomegalovirus-Specific Neutralizing and Fc Receptor-Binding Responses on Congenital Cytomegalovirus Transmission in HIV-Exposed Neonates. [PDF]
VirusesMiller IG +11 more
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FcRn: the neonatal Fc receptor comes of age [PDF]
Nature Reviews Immunology, 2007 The neonatal Fc receptor for IgG (FcRn) has been well characterized in the transfer of passive humoral immunity from a mother to her fetus. In addition, throughout life, FcRn protects IgG from degradation, thereby explaining the long half-life of this class of antibody in the serum. In recent years, it has become clear that FcRn is expressed in various
Roopenian, D C, Akilesh, S
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Colostrogenesis: Role and Mechanism of the Bovine Fc Receptor of the Neonate (FcRn)
Journal of Mammary Gland Biology and Neoplasia, 2021Colostrogenesis is a separate and unique phase of mammary epithelial cell activity occurring in the weeks before parturition and rather abruptly ending after birth in the bovine. It has been the focus of research to define what controls this process and how it produces high concentrations of specific biologically active components important for the ...
Craig R. Baumrucker +2 more
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The neonatal Fc receptor (FcRn) expression in the human skin
Virchows Archiv, 2007The neonatal Fc receptor, FcRn, has a wide expression within the human body, including adult cells; however, it is not ubiquitously expressed (reviewed in [2]). The receptor is involved both in IgG transcytosis as well as recycling, being able to bind both free and antigen complexed IgG molecules (reviewed in [4]). Cauza et al.
Petru Cianga +4 more
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The neonatal Fc receptor (FcRn) is expressed in the bovine lung
Veterinary Immunology and Immunopathology, 2004In neonatal calves, maternal immunoglobulin (Ig) is transferred into respiratory secretion which contributes to protection against pathogens. The early predominance of IgG1 in respiratory tract secretions is progressively reduced in favor of IgA by age but in the lower, bronchoalveolar system secreted IgG remains the dominant secreted Ig even in ...
Laszlo V. Frenyo +5 more
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Expression of the neonatal Fc receptor (FcRn) in the bovine mammary gland
Journal of Dairy Research, 2005In ruminants, protective immunoglobulins are transferred to the newborn via colostrum to mediate maternal immunity. There is a high selectivity in the transport of immunoglobulins from the maternal plasma across the mammary barrier into the colostrum, and only IgG1 is transferred in large amounts.
Imre Kacskovics +6 more
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Expression of the neonatal Fc receptor (FcRn) at the blood–brain barrier
Journal of Neurochemistry, 2002AbstractThe blood–brain barrier (BBB) restricts transport of immunoglobulin G (IgG) in the blood to brain direction. However, IgG undergoes rapid efflux in the brain to blood direction via reverse transcytosis across the BBB after direct intracerebral injection. This BBB IgG transport system has the characteristics of an Fc receptor (FcR), but there is
Chunni Zhu +2 more
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