Results 41 to 50 of about 69,213 (212)

Long‐Acting Therapeutics in Pediatric Health: Bridging Innovation and Access

Clinical Pharmacology &Therapeutics, EarlyView.
Children have distinct therapeutic needs arising from age‐dependent physiology, disease epidemiology, formulation requirements, dosing considerations, and safety vulnerabilities. Despite substantial reductions in childhood mortality over the past three decades, nearly 5 million children under five died in 2023, with infectious diseases continuing to ...
Prajith Venkatasubramanian, Moherndran Archary, Daniel B. Hawcutt, Rachel Daley, Edmund Capparelli, Adeniyi Olagunju   +5 more
wiley   +1 more source

Neonates with acute liver failure have higher overall mortality but similar posttransplant outcomes as older infants

Liver Transplantation, EarlyView., 2022
Abstract Neonatal acute liver failure (ALF) carries a high mortality rate; however, little data exist on its peritransplant hospital course. This project aimed to identify factors associated with outcomes in neonates with ALF using large multicenter databases.
Swati Antala, Bridget Whitehead, Justin Godown, Matt Hall, Anna Banc‐Husu, Estella M. Alonso, Sarah A. Taylor   +6 more
wiley   +1 more source

Clinical outcome and risk factors of neonatal sepsis among neonates in Felege Hiwot referral Hospital, Bahir Dar, Amhara Regional State, North West Ethiopia 2016: a retrospective chart review

BMC Research Notes, 2017
Background Sepsis remains a major cause of morbidity and mortality among neonates. The risk factors and clinical outcomes of sepsis are poorly understood.
Tilahun Tewabe, Seida Mohammed, Yibeltal Tilahun, Birhanie Melaku, Mequanint Fenta, Tsigiereda Dagnaw, Amare Belachew, Ashagre Molla, Habte Belete   +8 more
doaj   +1 more source

Incidence of Neonatal Sepsis in the Neonatal Intensive Care unit: A prospective study at Al Batool Teaching Hospital in Diyala Governorate

Diyala Journal of Medicine, 2020
Background:Sepsis is regarded as one of the most common causes of morbidity and mortality in neonates despite of recent advances in neonatal intensive care unit technologies.
Sura Qais Mahmood Almaroof, Imad Mahmood Enad, Shaima Hussein Alwan, Issam Tariq Abdul Wahaab   +3 more
doaj   +2 more sources

Prediction of subsequent seizures after acute symptomatic seizures in critically ill children: A clinical–electroencephalographic model

Epilepsia, EarlyView.
Abstract Objective We aimed to determine the risk of subsequent seizure or epilepsy diagnosis after acute symptomatic seizures (ASyS) in critically ill children, evaluate whether antiseizure medication (ASM) use is associated with subsequent seizure/epilepsy diagnosis, and develop a simple Seizure/Epilepsy Risk Score to predict subsequent seizure ...
Nicholas S. Abend, France W. Fung, Darshana S. Parikh, Mark Ramos, Rui Xiao, Alexis A. Topjian   +5 more
wiley   +1 more source

Comparative efficacy of micro-erythrocyte sedimentation rate (m-ESR) and C-reactive protein (CRP) as a neonatal septic screening marker—a single-center, retrospective observational study

Egyptian Pediatric Association Gazette, 2023
Background Neonatal sepsis is a clinical syndrome characterized by signs and symptoms of infection with or without accompanying bacteremia in neonatal period. Most of neonatal sepsis-related morbidity and mortality can be prevented by early diagnosis and
Thirunavukkarasu Arun Babu, Arundhathi Shankaralingappa, Vijayasankar Vijayadevagaran, Vijayan Sharmila, Vinoth Kumar Kalidoss   +4 more
doaj   +1 more source

Fatalities within seven days after equine standing sedation: A prospective, multicentre study

Equine Veterinary Journal, EarlyView.
Abstract Background Information regarding mortality associated with standing procedures in horses is sparse. Objectives To report data from >12,000 standing sedations. Study Design Confidential, observational, prospective, multicentre, cohort study.
Miguel Gozalo‐Marcilla, José I. Redondo, Polly M. Taylor, Luis Domenech, Javier Doménech, Gordon Mark Johnston, Regula Bettschart‐Wolfensberger   +6 more
wiley   +1 more source

Evaluate the diagnosis of neonatal sepsis by measuring interleukins: A systematic review

Pediatrics and Neonatology, 2018
Neonatal sepsis is a dangerous and common disease among infants which is associated with high morbidity and mortality. Interleukins may be helpful for diagnosis of neonatal sepsis.
Hassan Boskabadi, Maryam Zakerihamidi
doaj   +1 more source

Vaginal host–microbe signatures linked to placental outcomes in mares

Equine Veterinary Journal, EarlyView.
Abstract Background Ascending placentitis is a leading cause of late‐term pregnancy loss in mares. Although pathogens are presumed to ascend from the caudal reproductive tract, the association between the vaginal microbiome and placentitis has not been systematically examined.
Machteld van Heule, Babiche Heil, Jamie K. Norris, Kristene Gedye, Xiaoxiao Lin, Ward De Spiegelaere, Peter Daels, Pouya Dini   +7 more
wiley   +1 more source

Efficient management of neonatal sepsis diagnosis using predictive analytics methods: a scoping review

Healthcare in Low-resource Settings
Neonatal sepsis is a critical and life-threatening condition that significantly contributes to the high rates of illness and death among newborns, particularly in low- and middle-income countries (LMICs).
KVKL Narasimha Rao, Pradeep Kumar Dadabada, Sanjita Jaipuria   +2 more
doaj   +1 more source