Results 1 to 10 of about 445,411 (238)

Multizonal anogenital neoplasia in women: a cohort analysis

open access: yesBMC Cancer, 2021
Background There is currently a lack of information on full anogenital evaluation of women with a previous history of anogenital neoplasia. Methods Retrospective analysis of the Homerton Anogenital Neoplasia Service records from January 2012 to March ...
Andreia Albuquerque   +9 more
doaj   +1 more source

The Role of TGF-β in Bone Metastases

open access: yesBiomolecules, 2021
Complications associated with advanced cancer are a major clinical challenge and, if associated with bone metastases, worsen the prognosis and compromise the survival of the patients.
Trupti Trivedi   +3 more
doaj   +1 more source

Quantifying requirements for mitochondrial apoptosis in CAR T killing of cancer cells

open access: yesCell Death and Disease, 2023
Chimeric antigen receptor (CAR) T cell therapy is an FDA-approved treatment for several hematologic malignancies, yet not all patients respond to this treatment.
Alexandra L. Pourzia   +7 more
doaj   +1 more source

Translational Strategies to Target Metastatic Bone Disease

open access: yesCells, 2022
Metastatic bone disease is a common and devastating complication to cancer, confounding treatments and recovery efforts and presenting a significant barrier to de-escalating the adverse outcomes associated with disease progression.
Gabriel M. Pagnotti   +2 more
doaj   +1 more source

3D Models as a Tool to Assess the Anti-Tumor Efficacy of Therapeutic Antibodies: Advantages and Limitations

open access: yesAntibodies, 2022
Therapeutic monoclonal antibodies (mAbs) are an emerging and very active frontier in clinical oncology, with hundred molecules currently in use or being tested.
Virginia Guzzeloni   +4 more
doaj   +1 more source

Adjuvant therapy in adrenocortical carcinoma: prognostic factors and treatment options

open access: yesEndocrine Oncology, 2023
Adrenocortical carcinoma (ACC) is a rare cancer with high recurrence rates and heterogeneous clinical behavior. The role of adjuvant therapy remains unclear because of the challenges in collecting high-quality data for a rare cancer.
Ruaa Al-Ward   +2 more
doaj   +1 more source

Parathyroid adenoma versus primary hyperparathyroidism [PDF]

open access: yesRomanian Medical Journal, 2021
This is a narrative review of literature. We focus on the issue of identifying a parathyroid adenoma without anomalies of function (non-functioning parathyroid adenoma) which is incidentally detected or not, via routine neck ultrasound or through ...
Mihai Cristian Dumitrascu   +8 more
doaj   +1 more source

Faecal haemoglobin can define risk of colorectal neoplasia at surveillance colonoscopy in patients at increased risk of colorectal cancer. [PDF]

open access: yes, 2020
Background: Quantitative faecal immunochemical tests measure faecal haemoglobin concentration (f-Hb), which increases in the presence of colorectal neoplasia.Objective: We examined the diagnostic accuracy of faecal immunochemical test (FIT)in patients at
Cleary, Shirley   +9 more
core   +2 more sources

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