Results 91 to 100 of about 191,052 (217)

Comparison of self‐sampling versus clinician‐sampling HPV DNA cervical cancer screening in South African women living with and without HIV

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Introduction Human papilloma virus (HPV) testing is the preferred primary screening method for cervical cancer, and HPV self‐sampling has the potential to improve screening uptake. We compared the test performance and agreement of self‐ and clinician‐sampling HPV in women living with HIV (WLWH) and HIV‐negative women in Gauteng and Western ...
Leon C. Snyman, Cathy Visser, Gerrit J. Dreyer, Azwidowi Lukhwareni, F. Haynes van der Merwe, Matthys H. Botha, Karin Richter, Greta Dreyer   +7 more
wiley   +1 more source

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source

Tofacitinib Regulates β‐Catenin Nuclear Translocation to Inhibit FLS Migration and Alleviate Clinical Symptoms of RA

iNew Medicine, EarlyView.
ABSTRACT Objective Tofacitinib is a Janus kinase (JAK) inhibitor approved for the treatment of moderate‐to‐severe rheumatoid arthritis (RA). However, its synovium‐related molecular mechanisms, particularly its regulatory effect on fibroblast‐like synoviocyte (FLS) migration, remain incompletely understood.
Shuqi Fang, Tianjing Zhang, Ling Hu, Ruijin Liu, Leyi Jia, Menglin Bai, Jiale Dong, Yuchen Zhao, Han Wang, Lei Zhang, Tao Li, Youcai Deng, Xianzheng Zhang, Lingling Zhang   +13 more
wiley   +1 more source

The Crude Venom of the Whitetail Lancehead, Bothrops leucurus, and Two of Its Enzymatic Components Are Selectively Cytotoxic for Glioma Cells In Vitro

Journal of Applied Toxicology, EarlyView.
ABSTRACT Malignant glioma is the most common primary brain tumor, and glioblastoma multiforme (GBM) remains its most aggressive and incurable form. Snake venoms contain bioactive compounds with promising antitumoral properties against several cancer types.
M. O. H. V. Rosário, T. M. Fucase, P. J. Spencer, J. M. Sciani, J. Clarêncio, G. Rádis‐Baptista, L. L. Casais‐e‐Silva, R. S. El‐Bachá   +7 more
wiley   +1 more source

Intraoral myxoid fibrolipoma with chondroid areas: Diversified differentiation or a mere coincidence? [PDF]

Journal of Oral Health and Oral Epidemiology
Background: Oral mesenchymal tumors are uncommon lesions, presenting as slow-growing exophytic masses. Myxofibrolipoma(MFL) is a lipoma variant comprising mature fat cells admixed with variable quantities of mucinous and fibrous stroma.Case Presentation:
Hima Edupuganti, Archana Shetty, Vijaya Mysorekar, Sharmila G S, Aakanksha Koul   +4 more
doaj  

Repeated Exposure to a Hair Bleaching Mixture Alters cGAS–STING Pathway Transcripts in Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT Hair bleaching products commonly contain ammonia and hydrogen peroxide, chemicals capable of generating reactive oxygen species (ROS). However, their effects on innate immune signaling pathways associated with DNA damage remain poorly understood.
Leticia Rodrigues Sampaio, Marjori Lima Boblitz Parente, Ronald Feitosa Pinheiro   +2 more
wiley   +1 more source

High-throughput analysis of the T cell receptor gene repertoire in low-count monoclonal B cell lymphocytosis reveals a distinct profile from chronic lymphocytic leukemia

Haematologica, 2020
Andreas Agathangelidis, Chrysi Galigalidou, Lydia Scarfò, Theodoros Moysiadis, Alessandra Rovida, Elisavet Vlachonikola, Electra Sofou, Fotis Psomopoulos, Anna Vardi, Pamela Ranghetti, Alexandra Siorenta, Alex Galanis, Kostas Stamatopoulos, Anastasia Chatzidimitriou, Paolo Ghia   +14 more
doaj   +1 more source

Flow Cytometry‐Guided Diagnosis of Cortical T‐Lymphoblastic Lymphoma Presenting With a Massive Mediastinal Mass and Borderline Bone Marrow Involvement

Journal of Clinical Laboratory Analysis, EarlyView.
ABSTRACT Background T‐cell lymphoblastic lymphoma (T‐LBL) and T‐cell acute lymphoblastic leukemia (T‐ALL) are considered a single biological entity, distinguished primarily by the extent of bone marrow infiltration. This distinction becomes diagnostically challenging in patients with borderline marrow blast counts and predominantly extramedullary ...
Chen Glait‐Santar, Yakir Moshe, Itzhaki‐Alfia Ayelet, Ben‐Zion Katz   +3 more
wiley   +1 more source

Reimagining Dental Education for Planetary Health, One Health, and Environmental Sustainability: A Narrative Review With Case Studies

Journal of Dental Education, EarlyView.
ABSTRACT Oral health is shaped by environmental, social, and systemic determinants that extend well beyond clinical care. As frequent points of contact within the health system, oral health professionals are uniquely positioned to advance sustainable practices and holistic health policies.
Faizan Alawi, Jonathan Dixon, James Field, Nicolas Martin   +3 more
wiley   +1 more source

Bone-derived excess TGF-ß release is associated with cognitive dysfunction due to oxidation of RyR, Ca2+ leak and mitochondrial dysfunction

Journal of Bone Oncology
Lei Shi, Sukanya Suresh, Truc Kuo, Anand Singh, Jade Martinez, Trupti Trivedi, Gabriel M. Pagnotti, Leah D. Guerra, Xu Cao, Theresa A. Guise   +9 more
doaj   +1 more source