Results 101 to 110 of about 585,185 (390)

Use of the Intratumoural Anticancer Drug Tigilanol Tiglate in Two Horses

open access: yesFrontiers in Veterinary Science, 2020
Tigilanol tiglate is a novel small molecule approved as a veterinary pharmaceutical in Europe for intratumoural treatment of non-metastatic, non-resectable canine mast cell tumors.
Thomas De Ridder   +4 more
doaj   +1 more source

What Is the Risk of Anal Carcinoma in Patients With Anal Intraepithelial Neoplasia III?

open access: yesDiseases of the Colon & Rectum, 2018
BACKGROUND: The risk of anal carcinoma after previous diagnosis of anal intraepithelial neoplasia III is unclear. OBJECTIVE: The purpose of this study was to estimate the risk of anal carcinoma in patients with anal intraepithelial neoplasia III and to ...
Grace C. Lee   +7 more
semanticscholar   +1 more source

Non‐RASopathy Genetic Syndromes Identified as the Molecular Cause of Disease in Patients Previously Diagnosed With Noonan Syndrome

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Noonan Syndrome (NS) is a clinically and genetically heterogeneous condition characterized by typical facial dysmorphisms, short stature, congenital heart defects, and developmental delays. While variants in genes such as PTPN11, SOS1, and RAF1 account for most genetically confirmed cases, diagnosis is challenging due to phenotypic overlap ...
Gabriela Jeesoo Kim   +9 more
wiley   +1 more source

T-PLL Presenting with an Indolent Course

open access: yesCase Reports in Hematology
T-cell prolymphocytic leukemia (T-PLL) is a rare, mature T-cell leukemia which usually presents with aggressive behavior. We report an asymptomatic T-PLL patient diagnosed by clinical features, lymphocyte morphology, and flow cytometry. Incidentally, she
Arsa Thammahong   +2 more
doaj   +1 more source

Concomitant Presence of Ovarian Tumors (Teratoma and Granulosa Cell Tumor), and Pyometra in an English Bulldog Female Dog: A Case Report

open access: yesFrontiers in Veterinary Science, 2020
Background: The diagnosis of ovarian tumors in dogs is usually complicated because the clinical signs can be very discrete and can be easily confused with other diseases.
Carlos A. Oviedo-Peñata   +4 more
doaj   +1 more source

Is There a Causal Association between Genotoxicity and the Imposex Effect? [PDF]

open access: yes, 2006
There is a growing body of evidence that indicates common environmental pollutants are capable of disrupting reproductive and developmental processes by interfering with the actions of endogenous hormones.
Colborn T   +13 more
core   +2 more sources

Genomics Review of Selective RET Inhibitors Sensitivity in Thyroid Cancer Clinical Trials

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT RET gene is a driver of thyroid cancer (TC) tumorigenesis. The incidence of TC has increased worldwide in the last few decades, both in medullary and follicular‐derived subtypes. Several drugs, including multikinase and selective inhibitors, have been explored.
Sara Gil‐Bernabé   +5 more
wiley   +1 more source

Molecular diversity of bivalve transmissible neoplasia of blue mussels in the Kola Bay (Barents Sea) indicates a recent migration of the cancer lineages between the North Pacific and Northern Europe [PDF]

open access: green, 2023
Maria Skazina   +8 more
openalex   +1 more source

Sinonasal Sarcomas Management: An International Consensus Statement

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Introduction Sinonasal sarcomas are exceedingly rare entities, constituting less than 7% of head and neck sarcomas. Their complex histology needs specialized treatment, which is often based on multimodal approaches including surgery, radiation therapy, and/or chemotherapy.
Alessandro Vinciguerra   +51 more
wiley   +1 more source

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