Results 11 to 20 of about 553,772 (230)
Multizonal anogenital neoplasia in women: a cohort analysis
Background There is currently a lack of information on full anogenital evaluation of women with a previous history of anogenital neoplasia. Methods Retrospective analysis of the Homerton Anogenital Neoplasia Service records from January 2012 to March ...
Andreia Albuquerque +9 more
doaj +1 more source
The Role of TGF-β in Bone Metastases
Complications associated with advanced cancer are a major clinical challenge and, if associated with bone metastases, worsen the prognosis and compromise the survival of the patients.
Trupti Trivedi +3 more
doaj +1 more source
Quantifying requirements for mitochondrial apoptosis in CAR T killing of cancer cells
Chimeric antigen receptor (CAR) T cell therapy is an FDA-approved treatment for several hematologic malignancies, yet not all patients respond to this treatment.
Alexandra L. Pourzia +7 more
doaj +1 more source
Translational Strategies to Target Metastatic Bone Disease
Metastatic bone disease is a common and devastating complication to cancer, confounding treatments and recovery efforts and presenting a significant barrier to de-escalating the adverse outcomes associated with disease progression.
Gabriel M. Pagnotti +2 more
doaj +1 more source
Therapeutic monoclonal antibodies (mAbs) are an emerging and very active frontier in clinical oncology, with hundred molecules currently in use or being tested.
Virginia Guzzeloni +4 more
doaj +1 more source
Adjuvant therapy in adrenocortical carcinoma: prognostic factors and treatment options
Adrenocortical carcinoma (ACC) is a rare cancer with high recurrence rates and heterogeneous clinical behavior. The role of adjuvant therapy remains unclear because of the challenges in collecting high-quality data for a rare cancer.
Ruaa Al-Ward +2 more
doaj +1 more source
Immune checkpoint inhibitors, such as anti-cytotoxic T-lymphocyte–associated antigen-4 and anti-programmed death-1, are a type of cancer immunotherapy approved for late-stage malignancy treatment.
Anastasia Politi +4 more
doaj +1 more source
Summary: In this protocol, we describe how to generate 3D culture surrogates of chronic lymphocytic leukemia (CLL) and multiple myeloma (MM) bone marrow microenvironments. We detail the use of culturing scaffolds populated with BM stromal cells and tumor
Daniela Belloni +6 more
doaj +1 more source
Chemotherapy Associated Ovarian Failure
As the incidence of malignancies in young adults is increasing, fertility preservation in cancer survivors arises as a major concern. Especially among female cancer patients, pregnancy rates are estimated to be 40% lower compared to women of the same age.
Davide Mauri +10 more
doaj +1 more source
Background High resolution anoscopy (HRA) examination is regarded as the best method for the management of anal high grade squamous intraepithelial lesions to prevent anal squamous carcinoma.
Anke De-Masi +10 more
doaj +1 more source

