Results 61 to 70 of about 445,411 (238)

Disrupting pro-survival and inflammatory pathways with dimethyl fumarate sensitizes chronic lymphocytic leukemia to cell death

Cell Death and Disease
Microenvironmental signals strongly influence chronic lymphocytic leukemia (CLL) cells through the activation of distinct membrane receptors, such as B-cell receptors, and inflammatory receptors, such as Toll-like receptors (TLRs).
Maria Elena Mantione, Miriam Meloni, Ilenia Sana, Jessica Bordini, Martina Del Nero, Michela Riba, Pamela Ranghetti, Eleonora Perotta, Paolo Ghia, Lydia Scarfò, Marta Muzio   +10 more
doaj   +1 more source

A neuroendocrine cause for refractory symptoms in coeliac disease

JGH Open, 2021
Neuroendocrine tumours while rare, need to be considered in patients with chronic diarrhoea. Reported herein is a case of vasoactive intestinal peptideoma in a patient with refractory diarrhoea following a diagnosis of coeliac disease.
Hardesh Dhillon, Damian Dowling, Sina Alexander   +2 more
doaj   +1 more source

Genetic background influences tumour development in heterozygous Men1 knockout mice [PDF]

, 2020
Multiple endocrine neoplasia type 1 (MEN1), an autosomal dominant disorder caused by MEN1 germline mutations, is characterised by parathyroid, pancreatic and pituitary tumours. MEN1 mutations also cause familial isolated primary hyperparathyroidism (FIHP)
Christie, Paul T., Javid, Mahsa, Kooblall, Kreepa G., Lines, Kate E., Mallon, Ann-Marie, Newey, Paul J., Piret, Sian E., Reed, Anita Ac, Simon, Michelle, Stevenson, Mark, Thakker, Rajesh V., Walls, Gerard V.   +11 more
core   +2 more sources

P1489: HIGH DOSE IRON IMPAIRS MALIGNANT B-CELL VIABILITY AND IMPROVES IMMUNE ANTITUMOR FUNCTIONS IN CHRONIC LYMPHOCYTIC LEUKEMIA

HemaSphere, 2023
Jessica Bordini, Alessia Morabito, Caterina Taccetti, Chiara Lenzi, Pamela Ranghetti, Eleonora Perotta, Michela Frenquelli, Lydia Scarfò, Elisa Albi, Paolo Ghia, Alessandro Campanella   +10 more
doaj   +1 more source

Volumetric laser endomicroscopy and its application to Barrett's esophagus: results from a 1,000 patient registry. [PDF]

, 2019
Volumetric laser endomicroscopy (VLE) uses optical coherence tomography (OCT) for real-time, microscopic cross-sectional imaging. A US-based multi-center registry was constructed to prospectively collect data on patients undergoing upper endoscopy during
Berzin, T, Cash, B, Chang, K, DeMeester, S, Di Palma, JA, Diehl, D, Ganguly, E, Gonda, T, Gordon, S, Gress, F, Hagen, J, Hasan, M, Hawes, R, Hyder, S, Jobe, B, Joshi, V, Kahaleh, M, Kedia, P, Khara, H, Komatsu, Y, Konda, V, Lee, C, Lipham, J, Malik, Z, Mashimo, H, McKinley, M, Navaneethan, U, Oh, D, Pleskow, D, Poneros, J, Rodriguez, R, Rothstein, R, Samarasena, J, Sawhney, M, Schnoll-Sussman, F, Sejpal, DV, Sethi, A, Sharaiha, R, Sharzehi, K, Siddiqui, UD, Singh, S, Smith, MS, Tarnasky, P, Thakkar, S, Trindade, AJ, Wallace, M, Waxman, I, Wolfsen, H   +47 more
core  

MicroRNA-551b expression profile in low and high-grade cervical intraepithelial neoplasia [PDF]

, 2018
OBJECTIVE: To evaluate the expression of microRNA (miR)-551b in patients with low and high grade cervical intraepithelial neoplasia (CIN) and to find an association with high-risk Human Papillomavirus (HR-HPV) infection-related prognostic biomarkers ...
Bordi, G, Carico, E, Caserta, D, DE VITIS, C, DI PROPERZIO, M, Giglio, S, Lukic, A, Mancini, R.   +7 more
core   +1 more source

T-PLL Presenting with an Indolent Course

Case Reports in Hematology
T-cell prolymphocytic leukemia (T-PLL) is a rare, mature T-cell leukemia which usually presents with aggressive behavior. We report an asymptomatic T-PLL patient diagnosed by clinical features, lymphocyte morphology, and flow cytometry. Incidentally, she
Arsa Thammahong, Narittee Sukswai, Chantana Polprasert   +2 more
doaj   +1 more source

Metastatic Cholangiocarcinoma in a Bearded Dragon (Pogona vitticeps)

Acta Veterinaria, 2020
A 6.5-year-old female bearded dragon (Pogona vitticeps) was presented with a swollen right pelvic limb. A tissue core biopsy from the swollen area was performed and a presumptive histopathological diagnosis of adenocarcinoma was made.
Dominik Komenda, Tamara Dolenšek, Tanja Švara, Marjan Kastelic, Pavel Proks, Ivana Nývltová, Pavel Kvapil   +6 more
doaj   +1 more source

A systematic approach to cancer: evolution beyond selection. [PDF]

, 2017
Cancer is typically scrutinized as a pathological process characterized by chromosomal aberrations and clonal expansion subject to stochastic Darwinian selection within adaptive cellular ecosystems.
Miller, William B, Torday, John S
core   +1 more source

Is There a Causal Association between Genotoxicity and the Imposex Effect? [PDF]

, 2006
There is a growing body of evidence that indicates common environmental pollutants are capable of disrupting reproductive and developmental processes by interfering with the actions of endogenous hormones.
Colborn T, Collins MKL, Cooke H, Depledge MH, Gibbs PE, Harring KE, Harris JO, Josephine A. Hagger, Jörg Oehlmann, Laruelle F, Michael H. Depledge, Smith BS, Susan Jobling, Tamara S. Galloway   +13 more
core   +2 more sources