Results 61 to 70 of about 585,185 (390)
Advanced Science, EarlyView.In pancreatic cancer, the protein DKK3 is found to play a complex role: it initially slows early tumor growth but later promotes tumor aggressiveness. DKK3 expression evolves during progression and drives cancer severity by orchestrating cellular and molecular signaling pathways.
Dharini Srinivasan +20 more
wiley +1 more source
Kidney International, 1977 Proteinuria, often of sufficient magnitude to cause the nephrotic syndrome, is a recognized systemic manifestation of neoplastic diseases. The medical literature contains numerous examples of an apparent temporal relationship between the development of the nephrotic syndrome and the clinical appearance of a tumor. Many types of tumor have been reported,
Eagen, Jeremiah W., Lewis, Edmund J.
openaire +2 more sources
Gut, 2016 Background For endoscopic resection of early GI neoplasia, endoscopic submucosal dissection (ESD) achieves higher rates of complete resection (R0) than endoscopic mucosal resection (EMR).
G. Terheggen +7 more
semanticscholar +1 more source
CDH1 Orchestrates Anabolic Events to Promote Cell Cycle Initiation
Advanced Science, EarlyView.Cell proliferation requires the integration of cell cycle and anabolic signals. G1‐phase regulator CDH1 coordinates anabolism through the CDH1‐VHL‐AARS2/HIF1α axis, while CDH1‐accumulated R5P is sensed by TKTL1 to facilitate CDH1 degradation and cell cycle initiation, constituting a CDH1‐centered regulatory circuit.
Yun‐Zi Mao +18 more
wiley +1 more source
Journal of Veterinary Internal Medicine, 2021 A 10‐year‐old female spayed mixed breed dog was evaluated for diarrhea and vomiting. Diagnostic imaging demonstrated the presence of an intracardiac mass.
Joseph S. Raleigh +11 more
doaj +1 more source
Periacinar clefting and p63 immunostaining in prostatic intraepithelial neoplasia and prostatic carcinoma [PDF]
, 2006 The aim of the present study was to correlate the presence and extent of retraction clefting and the expression of p63 in neoplastic glands and glands with prostatic intraepithelial neoplasia (PIN) in needle core biopsies.
Belicza, Mladen +5 more
core +1 more source
Multiple endocrine neoplasia: an update
Internal medicine journal (Print), 2019 The multiple endocrine neoplasia (MEN) syndromes include MEN1, MEN2 (formerly MEN2A), MEN3 (formerly MEN2B) and the recently identified MEN4. Clinical presentations are varied and often relate to the overproduction of specific hormones. Understanding the
J. McDonnell +3 more
semanticscholar +1 more source
Targeted Expansion of Treg Cells to Induce Immune Tolerance after Kidney Transplantation
Advanced Science, EarlyView.A dual‐targeting nanoparticle platform that selectively engages graft stromal cells via CD248 receptors while employing kidney‐ specific promoters (NPHS2) to drive localized IL‐ 2/TGF‐βexpression is developed. This approach achieves three therapeutic objectives:1) intragraft Treg polarization without systemic cytokine exposure;2) reduced dependence on ...
Tong Lu +18 more
wiley +1 more source
A Field‐Deployable RotEx‐LAMP‐LFA Platform for Molecular Triage of HPV‐Driven Oncogenesis
Advanced Science, EarlyView.This study presents RotEx‐LAMP‐LFA, a fully integrated, battery‐powered, low‐cost point‐of‐care device for rapid cervical cancer risk detection based on HPV16/18 E6/E7 mRNA. Clinically validated, the system demonstrated high sensitivity and specificity, and showed full concordance between self‐collected and clinician‐collected samples, offering a ...
Yuan Gao +10 more
wiley +1 more source
Laparoscopic‐assisted cutaneous ureterostomy in a canine patient with prostatic carcinoma
Veterinary Medicine and Science, 2021 A 9‐year‐old neutered male Dachshund dog was assessed for stranguria. An enlarged prostate was identified on physical examination, and a diagnosis of prostatic carcinoma confirmed by cytology.
Giovanni Allevi +3 more
doaj +1 more source