Results 101 to 110 of about 2,228,127 (334)

Socio-economic inequalities in survival of patients with prostate cancer: role of age and Gleason grade at diagnosis [PDF]

, 2013
In the United Kingdom, survival of prostate cancer patients has improved since the 1990s. A deprivation gap in survival (better survival for the least deprived compared with the most deprived) has been reported but it is not known if differential ...
Morrison, D., Shafique, M.
core   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Identification of Clinically Significant Prostate Cancer by Combined PCA3 and AMACR mRNA Detection in Urine Samples

Research and Reports in Urology, 2020
Elena S Kotova,1 Yulia A Savochkina,2 Yuriy V Doludin,3 Alexander O Vasilyev,4 Elena A Prilepskay,4 Natalia V Potoldykova,3 Konstantin A Babalyan,1 Alexandra V Kanygina,1 Andrey O Morozov,3 Alexander V Govorov,4 Dmitry V Enikeev,3 Elena S Kostryukova,1 ...
Kotova ES, Savochkina YA, Doludin YV, Vasilyev AO, Prilepskay EA, Potoldykova NV, Babalyan KA, Kanygina AV, Morozov AO, Govorov AV, Enikeev DV, Kostryukova ES, Ilina EN, Govorun VM, Pushkar DY, Sharova EI   +15 more
doaj  

Histopathological Study of Canine Mammary Tumours with Different Stain Tecniques [PDF]

, 2018
Mammary gland cancer is the most frequent Malignant tumor in human females and bitches and morbidity and mortality due to it continue to increase. Mammary gland carcinomas are quite heterogeneous in terms of morphology and biological behavior.
Dhaskali, L. (Luljeta), Mazari, B. (Brunilda), Qoku, A. (Alketa)   +2 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Inter/Intra-Observer Reproducibility of Gleason Scoring in Prostate Adenocarcinoma in Iranian Pathologists

Urology Journal, 2012
PURPOSE: To measure the level of inter/intra-observer reproducibility among pathologists as far as Gleason scoring of adenocarcinoma of the prostate is concerned. MATERIALS AND METHODS: A total of 101 prostate biopsy slides, diagnosed with adenocarcinoma
Hassan Hosseinzadeh, Mohammadreza Bakhshandeh, Ali Ahmadi, Hedieh Moradi-Tabriz, Sara Sheikhbahaei, Alipasha Meysamie, Alireza Abdollahi   +6 more
doaj  

Predictive factors of unfavorable prostate cancer in patients who underwent prostatectomy but eligible for active surveillance

Prostate International, 2014
To investigate the predictive factors of unfavorable prostate cancer in Korean men who underwent radical prostatectomy but eligible for active surveillance according to Epstein criteria.
Seol Ho Choo, Hwang Gyun Jeon, Byong Chang Jeong, Seong Il Seo, Seong Soo Jeon, Han Yong Choi, Hyun Moo Lee   +6 more
doaj   +1 more source

A Phase II Basket Trial of Dual Anti-CTLA-4 and Anti-PD-1 Blockade in Rare Tumors (DART SWOG 1609) in Patients with Nonpancreatic Neuroendocrine Tumors. [PDF]

, 2020
PurposeImmune checkpoint blockade has improved outcomes across tumor types; little is known about the efficacy of these agents in rare tumors. We report the results of the (nonpancreatic) neuroendocrine neoplasm cohort of SWOG S1609 dual anti-CTLA-4 and ...
Baghdadi, Tareq Al, Blanke, Charles D, Chae, Young Kwang, Chen, Helen X, Fontaine, Annette, Gatalica, Zoran, Giles, Francis J, Hansel, Donna E, Hayward, Jourdain, Kasi, Anup, Korn, W Michael, Kurzrock, Razelle, Matrana, Marc, Mayerson, Edward, McLeod, Christine, Othus, Megan, Patel, Sandip P, Plets, Melissa, Ryan, Christopher W, Shah, Manisha H, Sharon, Elad, Singh, Preet Paul   +21 more
core  

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Factors correlating with lymph node metastases in patients with T1 ductal invasive breast cancer [PDF]

, 2006
BACKGROUND: Identification of reliable predictors of axillary lymph node metastases (ALNM) may be useful in selecting appropriate management for patients with T1-size breast cancer.
Ivković-Kapicl Tatjana, Knežević-Ušaj Slavica, Ninčić Dejan, Panjković Milana   +3 more
core   +1 more source