Seprase: An overview of an important matrix serine protease [PDF]
Seprase or Fibroblast Activation Protein (FAP) is an integral membrane serine peptidase, which has been shown to have gelatinase activity. Seprase has a dual function in tumour progression.
Abbott+115 more
core +1 more source
Uterine Rupture Due to Invasive Metastatic Gestational Trophoblastic Neoplasm [PDF]
While complete molar pregnancies are rare, they are wrought with a host of potential complications to include invasive gestational trophoblastic neoplasia. Persistent gestational trophoblastic disease following molar pregnancy is a potentially fatal complication that must be recognized early and treated aggressively for both immediate and long-term ...
Bruner, David I+2 more
openaire +6 more sources
Edge effects in game theoretic dynamics of spatially structured tumours [PDF]
Background: Analysing tumour architecture for metastatic potential usually focuses on phenotypic differences due to cellular morphology or specific genetic mutations, but often ignore the cell's position within the heterogeneous substructure.
Basanta, David+2 more
core +1 more source
Ultrasonographic criteria for the major salivary glands: a perspective for the application of new technologies [PDF]
It emerges from the interesting recent article by David et al. (4) on high-resolution ultrasound is the first line examination for parotid gland diffuse disease and focal lesions, normally using grey-scale and color-Doppler ultrasound especially using
Messineo, Daniela
core +1 more source
CRISPR/Cas9 mediated knockout of rb1 and rbl1 leads to rapid and penetrant retinoblastoma development in Xenopus tropicalis [PDF]
Retinoblastoma is a pediatric eye tumor in which bi-allelic inactivation of the Retinoblastoma 1 (RB1) gene is the initiating genetic lesion. Although recently curative rates of retinoblastoma have increased, there are at this time no molecular targeted ...
Boel, Annekatrien+12 more
core +2 more sources
Intraductal papillary mucinous neoplasms of the pancreas: Uncommon imaging presentation, evolution and comparison of guidelines [PDF]
Pancreatic cystic lesions are often asymptomatic, incidentally detected and include a range of entities with varying degrees of concern for malignancy.
Balducci F.+7 more
core +1 more source
Predictive factors for invasive intraductal papillary mucinous neoplasm of the pancreas [PDF]
Intraductal papillary mucinous neoplasm (IPMN) of the pancreas has malignant potential. Predicting invasive IPMN has proven difficult and controversial. We tried to identify predictive factors for invasive IPMN.Thirty six patients underwent resection for IPMN from February 2001 to July 2011.
Young Kook Yun+8 more
openaire +2 more sources
Clinical reasoning in canine spinal disease: what combination of clinical information is useful? [PDF]
Spinal disease in dogs is commonly encountered in veterinary practice. Numerous diseases may cause similar clinical signs and presenting histories. The study objective was to use statistical models to identify combinations of discrete parameters from the
ABRAMSON+36 more
core +2 more sources
DACH1 suppresses breast cancer as a negative regulator of CD44. [PDF]
Dachshund homolog 1 (DACH1), a key cell fate determination factor, contributes to tumorigenesis, invasion, metastasis of human breast neoplasm. However, the exact molecular mechanisms for the anti-tumor roles of DACH1 in breast carcinoma are still lack ...
Kuang, Dong+6 more
core +2 more sources
Keratocystic odontogenic tumor overexpresses invadopodia-related proteins, suggesting invadopodia formation [PDF]
OBJECTIVE: Keratocystic odontogenic tumor (KOT) is an odontogenic neoplasm that shows aggressive clinical behavior and local invasiveness. Invadopodia are actin-rich cellular protrusions exhibiting proteolytic pericellular activity, thereby inducing ...
Brasil da Silva, W+8 more
core +1 more source