Results 91 to 100 of about 485,459 (299)
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
CLINICAL STUDIES ON LYMPHANGIOGRAPHY FOR MALIGNANT NEOPLASM OF UROGENITAL ORGANS [PDF]
, 1975 Lymph node dissection was applied to 25 cases of malignant neoplasm of urogenital Organs and 517 lymph nodes dissected were studied in comparison with pre-operative lymphangiogram and the results were statistically analysed.
出村, 愰
core
A Rare Case of Thyroid Metastasis from Pancreatic Adenocarcinoma [PDF]
, 2011 Context Thyroid metastasis from pancreatic adenocarcinoma is extremely rare, with only two previous cases in the literature. We report a case of pancreatic adenocarcinoma metastasising to the thyroid. We review the incidence, diagnosis, and management of
Swan, Niall +4 more
core +2 more sources
Clinical Case ReportsThis case reports a rare co‐occurrence of pancreatic intraductal papillary mucinous neoplasm with invasive carcinoma and ampullary neuroendocrine tumor. Laparoscopic pancreaticoduodenectomy was done. No recurrence/metastasis in 12‐month follow‐up, though
Jingcheng Zhang +4 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Unusual Presentation of Differentiated Thyroid Cancer Metastasis
International Archives of Otorhinolaryngology, 2018 Introduction The rates of thyroid cancers are on a rise, especially well-differentiated thyroid cancers. This could be partly due to newer diagnostic modalities, like high-resolution ultrasound, that can pick up smaller lesions.
Haissan Iftikhar +3 more
doaj +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Renal cell carcinoma metastasis to thyroid tumor: a case report and review of the literature [PDF]
, 2013 Introduction. Metastatic neoplasms to the thyroid gland are rare in clinical practice. Clear cell renal carcinoma is the most frequent site of origin of thyroid metastases and represents 12-34% of all secondary thyroid tumours.
CALO', PIETRO GIORGIO +5 more
core +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source