Results 31 to 40 of about 494,128 (290)

Expression of Autophagy-Related Proteins in Hürthle Cell Neoplasm Is Different from That in Follicular Neoplasm [PDF]

open access: yesDisease Markers, 2017
Purpose. We aimed to evaluate expression of autophagy-related proteins in Hürthle cell neoplasm (HCN) and follicular neoplasm (FN) and assess the clinical implications. Methods. 265 FNs (112 follicular carcinomas and 153 follicular adenomas) and 108 HCNs (27 Hürthle cell carcinomas and 81 Hürthle cell adenomas) were made into a tissue microarray ...
Yoon Jin Cha, Hye Min Kim, Ja Seung Koo
openaire   +3 more sources

Role of hypoxia-related proteins in adenoid cystic carcinoma invasion

open access: yesDiagnostic Pathology, 2020
Background Among cancers affecting the oral cavity, adenoid cystic carcinoma (ACC) is a relatively common malignant neoplasm. It has high rates of metastasis and recurrence and is associated with significant morbidity.
Raíssa Pinheiro de Mendonça   +9 more
doaj   +1 more source

Neoplastic signatures: Comparative proteomics of canine hepatobiliary neuroendocrine tumors to normal niche tissue.

open access: yesPLoS ONE, 2023
Hepatobiliary neuroendocrine neoplasms are rare cancers in humans and dogs. To date, no large-scale primary hepatobiliary neoplasm omics analyses exist in any species.
Tifini L Batts   +9 more
doaj   +1 more source

Immunolocalization of the Bcl-2 protein within hematopoietic neoplasms [PDF]

open access: yesBlood, 1991
Abstract The Bcl-2 proto-oncogene was discovered at the t(14;18) breakpoint found in most follicular B-cell lymphomas and some diffuse large-cell lymphomas. Bcl-2 is unique among proto-oncogenes, being localized to mitochondria and extending cell survival by blocking programmed cell death.
M, Zutter   +3 more
openaire   +3 more sources

Consequences of a high incidence of microsatellite instability and BRAF‐mutated tumors: A population‐based cohort of metastatic colorectal cancer patients

open access: yesCancer Medicine, 2019
Background Immunotherapy for patients with microsatellite‐instable (MSI‐H) tumors or BRAF‐inhibitors combination treatment for BRAF‐mutated (mutBRAF) tumors in metastatic colorectal cancer (mCRC) is promising, but the frequency of these molecular changes
Kristine Ø. Aasebø   +9 more
doaj   +1 more source

Pleural effusion as first extra-medullary clinical presentation of an occult multiple myeloma: The role of medical thoracoscopy

open access: yesRespiratory Medicine Case Reports, 2020
Multiple myeloma is a malignant neoplasm of plasma cells that usually invades the bone marrow replacing normal bone marrow and producing large amounts of light chains of immunoglobulins (Ig) [1]. Clinical manifestations are related to the accumulation of
Antonietta Coppola   +10 more
doaj   +1 more source

Expression of cdc25A and cdc25B proteins in thyroid neoplasms [PDF]

open access: yesBritish Journal of Cancer, 2002
Cdc25B and cdc25A phosphates are prominent stimulators of cell cycle progression and recent studies have also suggested their oncogenic roles. To elucidate the role of these proteins in thyroid neoplasms, we immunohistochemically investigated their expression, and neither protein was expressed in normal follicular cells.
Ito, Y   +10 more
openaire   +2 more sources

Expression of Glucose Metabolism-Related Proteins in Adrenal Neoplasms

open access: yesPathobiology, 2021
<b><i>Purpose:</i></b> The aim of this study was to investigate the expression patterns of glucose metabolism-related proteins and their clinicopathologic implications in adrenal cortical neoplasms (ACN) and pheochromocytoma (PCC).
Eun Kyung, Kim   +2 more
openaire   +3 more sources

An Ulcerated Reddish Nodule of the Chest: When You See, Think …

open access: yesDermatopathology, 2018
A 97-year-old man with a previous personal history of multiple nonmelanoma skin cancers presented with a fast-growing, ulcerated reddish nodule on his chest.
Giulia Maria Ravaioli   +4 more
doaj   +1 more source

Mcl-1 Inhibition: Managing Malignancy in Multiple Myeloma

open access: yesFrontiers in Pharmacology, 2021
Multiple myeloma (MM) is a plasma cells neoplasm. The overexpression of Bcl-2 family proteins, particularly myeloid cell leukemia 1 (Mcl-1), plays a critical role in the pathogenesis of MM.
Omar S. Al-Odat   +12 more
doaj   +1 more source

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