Results 71 to 80 of about 386,493 (313)

Odontoameloblastoma with extensive chondroid matrix deposition in a guinea pig [PDF]

, 2018
Odontoameloblastomas (previously incorporated within ameloblastic odontomas) are matrix-producing odontogenic mixed tumors and are closely related in histologic appearance to the 2 other types of matrix-producing odontogenic mixed tumors: odontomas and ...
Hedley, J, Murphy, B, Priestnall, S L, Stapleton, N, Wong, H E   +4 more
core   +1 more source

Order-of-mutation effects on cancer progression: models for myeloproliferative neoplasm [PDF]

arXiv, 2023
We develop a modeling framework for cancer progression that distinguishes the order of two possible mutations. Recent observations and information on myeloproliferative neoplasms are analyzed within our framework. In some patients with myeloproliferative neoplasms, two genetic mutations can be found, JAK2 V617F and TET2.
arxiv  

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

Molecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas, Konstantinos Voutetakis, Vivian Kosmidou, Spyridon Tsikalakis, Spyridon Roditis, Konstantinos Pateas, Ryangguk Kim, Kymberleigh Pagel, Stephan Wolf, Gregor Warsow, Antonia Dimitrakopoulou‐Strauss, Georgios N. Zografos, Alexander Pintzas, Johannes Betge, Olga Papadodima, Stefan Wiemann   +15 more
wiley   +1 more source

Clear cell sarcoma of the esophagus: A rare location

Clinical Case Reports, 2020
Clear cell sarcoma of the esophagus is very rare. The etiology of this neoplasm remains unknown. Confirmed diagnosis requires histopathology with immunochemistry and molecular study.
Yosra Yahyaoui, Yosr Zenzri, Khalil Behi, Nadia Boujelbene, Amina Mokrani, Imen Abbas, Karima Mrad, Amel Mezlini   +7 more
doaj   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Surgery results in low relapse and progression rates in extramedullary plasmacytoma of the head and neck: A case cohort and review of the literature

Hematology Reports, 2020
Extramedullary plasmacytoma of the head and neck is a rare indolent neoplasm. Radiotherapy is often the preferred treatment option with excellent local control and survival.
Matevz Skerget, Tadej Dovsak, Gregor Kos, Samo Zver   +3 more
doaj   +1 more source

Interneurons accelerate learning dynamics in recurrent neural networks for statistical adaptation [PDF]

arXiv, 2022
Early sensory systems in the brain rapidly adapt to fluctuating input statistics, which requires recurrent communication between neurons. Mechanistically, such recurrent communication is often indirect and mediated by local interneurons. In this work, we explore the computational benefits of mediating recurrent communication via interneurons compared ...
arxiv  

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Characterization of efficacy and toxicity after high-dose pelvic reirradiation with palliative intent for genitourinary second malignant neoplasms or local recurrences after full-dose radiation therapy in the pelvis: A high-volume cancer center experience [PDF]

Advances in Radiation Oncology, 2017
The use of large-field external beam reirradiation (re-RT) after pelvic radiation therapy (RT) for genitourinary (GU) cancers has not been reported. We report the results of such treatment in patients with either symptomatic GU second malignant neoplasms or locally recurrent pelvic tumors after initial RT for whom surgery or further systemic therapy ...
Neil E. Martin, Neil E. Martin, Paul L. Nguyen, Paul L. Nguyen, Vinayak Muralidhar, Sarah Faso, Sophia C. Kamran, Akila N. Viswanathan, Akila N. Viswanathan, Clair J. Beard, Clair J. Beard, Mandar S. Bhagwat, Stephanie K. La Follette, Jason A. Efstathiou, Lauren C. Harshman   +14 more
openaire   +4 more sources

Serum anti-Müllerian hormone concentrations before and after treatment of an ovarian granulosa cell tumour in a cat [PDF]

, 2017
Case summary A 15-year-old female cat was presented for investigation of progressive behavioural changes, polyuria, polydipsia and periuria. An ovarian granulosa cell tumour was identified and the cat underwent therapeutic ovariohysterectomy (OHE).
Fowkes, R C, Garden, O A, Heaps, L A, Lipscomb, V J, Martineau, H, Priestnall, S L, Scudder, C J, Steinbach, S M L, Szladovits, B   +8 more
core   +2 more sources