Results 111 to 120 of about 364,324 (267)
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Cervical Angiomatoid Fibrous Histiocytoma [PDF]
, 2012 Background: Angiomatoid fibrous histiocytoma (AFH) is a rare type of sarcoma with low-grade malignancy thatusually occurs in young subjects. AFH is uncommon in the head and neck region.Methods: We describe an exceptional case of localization in the neck.
Arnaud, Sebestian +3 more
core +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Frontiers in OncologyObjectiveTo evaluate the value of Gd-EOB-DTPA-enhanced MRI in the early diagnosis of occult intrahepatic recurrence after curative ablation for hepatocellular carcinoma (HCC).Materials and methodsThis retrospective study included 74 HCC patients who ...
Zhi Zhu +7 more
doaj +1 more source
Angiolymphoid hyperplasia with eosinophilia treated with Mohs micrographic surgery [PDF]
, 2019 A 60-year-old healthy man presented with several enlarging, tender, spontaneously bleeding, and episodically pruritic nodules on his ear. Five agminated pink-red papulonodules of the superior postauricular sulcus were noted on examination.
DeWitt, Corey M +3 more
core
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Fifth‐Time Recurrence of Dermatofibrosarcoma Protuberans at Distinct Sites: A Rare Case Report
Clinical Case ReportsDermatofibrosarcoma protuberans is a rare dermal sarcoma with high local recurrence and rare metastasis. Our case highlights unusually frequent recurrences at different trunk sites over 8 years, including fibrosarcomatous transformation and nodal ...
Hamna Tariq +2 more
doaj +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
대한영상의학회지, 2019 Granulocytic sarcoma is a form of extramedullary involvement of primitive myeloid cells. A 69-year-old male patient, with history of acute myeloid leukemia (AML) in remission state for 4 years, presented numbness, radiating pain and progressive motor ...
Seung Eun Lee +3 more
doaj +1 more source
Full Issue: Volume 13, Issue 1 - Winter 2018 [PDF]
, 2018 Full Issue: Volume 13, Issue 1 - Winter ...
core +1 more source