Results 111 to 120 of about 571,072 (310)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Maximum Likelihood Estimation of the Prevalence of nonlethal Neoplasms [PDF]
, 1982 Kellerer, Albrecht M. +3 more
core +1 more source
Clinical Application and Advances in Radiofrequency Ablation of Lung Neoplasms
, 2010 Lung cancer is the leading cause of cancer-related mortality worldwide. In recent years, radiofrequency ablation (RFA), as a minimally invasive therapy, has been increasing utilized as a non-surgical treatment option for patients with primary and ...
Yong ZHANG, Xiaoqun LI
core +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Myeloid neoplasms and autoimmune diseases: markers of association
, 2021 Objective To investigate the prognostic significance of concomitant autoimmune diseases (ADs) in myeloproliferative neoplasms (MPNs). Methods 435 subjects with a diagnosis of MPNs were included in this observational single institution longitudinal ...
Galimberti, Sara +11 more
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
, 2015 Hydroxyurea as an indirect antithrombotic agent: In Myeloproliferative neoplasms (MPNs) thrombosis is an important cause of morbidity and mortality and some experimental studies reported an indirect, but significant, anti-thrombotic efficacy of ...
Landolfi, Raffaele +1 more
core +1 more source
An agenda for future research projects in polycythemia vera and essential thrombocythemia
Haematologica, 2020 Tiziano Barbui +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source