Results 71 to 80 of about 11,257 (224)

Biology of childhood germ cell tumours, focussing on the significance of microRNAs. [PDF]

, 2014
Genomic and protein-coding transcriptomic data have suggested that germ cell tumours (GCTs) of childhood are biologically distinct from those of adulthood.
Coleman, N, Murray, MJ, Nicholson, JC
core   +2 more sources

Structural and Biological Insights Into Copper(I) Phosphane Complexes With Boron‐Phenylated Poly(3‐(CF3)Pyrazolyl)‐ and Poly(6‐(CF3)‐2‐pyridyl)‐Borates

Chemistry – A European Journal, EarlyView.
This study reports six new copper(I) complexes with unusual coordination and strong anticancer activity against a panel of human cancer cell lines derived from different solid tumors. The most active compounds outperform cisplatin, even in resistant cells, by inhibiting protein disulfide isomerase and inducing redox stress that triggers non‐apoptotic ...
Vo Quang Huy Phan, Jo’ Del Gobbo, Mukundam Vanga, Deepika V. Karade, Cristina Marzano, Valentina Gandin, Laura Rigon, Carlo Santini, Maura Pellei, H. V. Rasika Dias   +9 more
wiley   +1 more source

Challenges and Pitfalls to Diagnosing NUTM1‐Rearranged Neoplasia of the Pancreas by Cytology and Ancillary Studies

Diagnostic Cytopathology, EarlyView.
ABSTRACT Fine‐needle aspiration cytology specimens are frequently utilized for ancillary studies to identify diagnostic and prognostic information. This case highlights diagnostic pitfalls and challenges in diagnosing NUTM1‐rearranged neoplasia on pancreatic cytology.
Terrance J. Lynn
wiley   +1 more source

The MyD88+ phenotype is an adverse prognostic factor in epithelial ovarian cancer [PDF]

, 2014
The prognosis of epithelial ovarian cancer is poor in part due to the high frequency of chemoresistance. Recent evidence points to the Toll-like receptor-4 (TLR4), and particularly its adaptor protein MyD88, as one potential mediator of this resistance ...
Barry-O'Crowley, Jacqui, Bates, Mark, Cooke, Aoife A., Costello, Katie M., D'Arcy, Tom, D’Adhemar, Charles J., Ffrench, Brendan, Finn, Stephen, Flood, Brian, Gallagher, Michael F., Gleeson, Noreen, Haley, Kathryn, Hennessy, Bryan T., Kernan, Niamh, Martin, Cara M., McCann, Amanda, Murphy, Ciara, O'Byrne, Ken, O'Donnell, Dearbhaile, O'Leary, John J., O'Neill, Luke A. J., O'Toole, Sharon, Pennington, Stephen, Sheils, Orla, Smyth, Paul C., Spillane, Cathy D., Stordal, Britta K.   +26 more
core   +3 more sources

Supposed pituitary-production of human chorionic Gonadotropin induced by androgen deprivation therapy

International Brazilian Journal of Urology
Introduction: The main cause of slightly elevated human chorionic gonadotropin (HCG) after successful treatment of male germ cell tumors is considered to be pituitary-derived HCG.
Koji Yoshimura, Yoshiharu Nakashima, Kyohei Sugiyama, Naoki Kohei, Akitoshi Takizawa   +4 more
doaj   +1 more source

Spatiotemporal cellular dynamics of the notochord shape intervertebral disc morphogenesis in the mouse embryo through apoptosis and proliferation

Developmental Dynamics, EarlyView.
Abstract Background The notochord is a midline structure essential for vertebrate embryogenesis, contributing to the development of the nervous system, digestive tract, and vertebral column. In particular, notochord signaling is indispensable for proper patterning and coordinated development of alternating vertebrae and intervertebral discs (IVDs ...
Julie Warin, Estelle Balissat, Pauline Colombier, Lily Paillat, Maeva Dutilleul, Anne Camus   +5 more
wiley   +1 more source

Central nervous system tumours in children in Ibadan, Nigeria: a histopathologic study

The Pan African Medical Journal, 2016
INTRODUCTION: contrary to some earlier teachings that central nervous system (CNS) tumours are uncommon in black children, these neoplasms are the fourth most common paediatric tumours in Ibadan. Our centre is the major referral centre for CNS tumours in
Gabriel Olabiyi Ogun, Amos Olufemi Adeleye, Olaosebikan Babatunde, Olufunmilola Abimbola Ogun, Ayodeji Salami, Biobele Jotham Brown, Effiong Akang   +6 more
doaj   +1 more source

Umbilical KeyPort bilateral laparoscopic orchiectomy in patient with complete androgen insensitivity syndrome

International Brazilian Journal of Urology, 2012
MAIN FINDINGS: A 22-year-old woman with complete androgen insensitivity syndrome (CAIS) presenting with primary amenorrhea and normal female external genitalia was referred for laparoscopic gonadectomy.
Felipe P. Andrade, Pedro M. Cabrera, Felipe Cáceres, Belen Gil, José M. Rodríguez-Barbero, Javier C. Angulo   +5 more
doaj   +1 more source

Buck Wheat: Nutritional, Bioactive Characteristics, Health Benefits, and Side Effects

Future Postharvest and Food, EarlyView.
ABSTRACT Micronutrient deficits have resulted from an over‐reliance on a small number of cereal crops for food security. The agricultural sector faces severe sustainability issues due to the rapid growth of the world's population and sudden climatic changes.
Momina Farooq, Sajad Ahmad Mir, Zahida Naseem   +2 more
wiley   +1 more source

Clinical analysis of 28 cases with pediatric germ cell tumors in pineal region

Chinese Journal of Contemporary Neurology and Neurosurgery, 2020
Objective To summarize the treatment methods and effects of pediatric germ cell tumors in pineal region. Methods and Results Clinical data of 28 children with primary intracranial pineal region germ cell tumors from March 2012 to December 2019 were ...
Ju⁃lei WANG, Tao HUANG, Qi⁃long TIAN, Jia⁃hua ZHOU, Liang WANG, Yan QU   +5 more
doaj