Results 61 to 70 of about 9,124 (231)

Protein Glutamylation: From Cytoskeleton to Signaling

open access: yesMed Research, EarlyView.
Tubulin glutamylation, γ‐glutamylation, and nontubulin glutamylation are distinct yet interconnected post‐translational modifications that regulate diverse physiological and pathological processes, including cytoskeletal organization, cell cycle progression, immunity, metabolism, and disease development.
Jiayuan Chen   +4 more
wiley   +1 more source

Giant Mediastinal Teratoma in a Child: A Case Report With a Brief Review of the Literature

open access: yesClinical Case Reports
Giant mediastinal teratomas in the pediatric population are uncommon entities that may grow insidiously and cause significant compression of intrathoracic structures.
Urías Hernandez Lopez   +5 more
doaj   +1 more source

Programmed cell death in response to chemotherapeutic agents in human germ cell tumour lines

open access: yes, 1995
Testicular germ cell tumours are amongst the most chemosensitive neoplasms both in vivo and in vitro. In the present study we demonstrate that following exposure to drugs used in chemotherapeutic treatment of testicular germ cell cancer tumour cells ...
Robertson, D.   +11 more
core   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli   +5 more
wiley   +1 more source

Supposed pituitary-production of human chorionic Gonadotropin induced by androgen deprivation therapy

open access: yesInternational Brazilian Journal of Urology
Introduction: The main cause of slightly elevated human chorionic gonadotropin (HCG) after successful treatment of male germ cell tumors is considered to be pituitary-derived HCG.
Koji Yoshimura   +4 more
doaj   +1 more source

Adult granulosa cell tumor of the testis masquerading as hydrocele

open access: yesInternational Brazilian Journal of Urology, 2015
Adult testicular granulosa cell tumor is a rare, potentially malignant sex cord-stromal tumor, of which 30 cases have been described to date. We report the case of a 43-year-old male who complained of a left testicular swelling. Scrotal ultrasound showed
Archana George Vallonthaiel   +4 more
doaj   +1 more source

D2-40 immunohistochemistry in the differential diagnosis of seminoma and embryonal carcinoma: A comparative immunohistochemical study with KIT (CD117) and CD30

open access: yes, 2007
The distinction between seminoma and embryonal carcinoma based on morphology alone can sometimes be problematic, requiring the use of immunohistochemistry to facilitate diagnosis.
Weiss, Lawrence M.   +2 more
core   +1 more source

Indications and Efficacy of Progestogen‐Monotherapy as Menopause Hormone Therapy: A Narrative Review

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Menopausal hormone therapy (MHT) remains the most effective treatment for vasomotor symptoms (VMS) and other manifestations of menopause; however, its use is limited in women with contraindications to oestrogen. Progestogen monotherapy, though historically underutilized, represents a viable alternative in this population. This narrative review
Chloe Thomas   +3 more
wiley   +1 more source

UDC: 616.681-006:615.38:616-06 DOI: 10.2298/AOO0902025G

open access: yes, 2014
Testicular neoplasms metastasizing to the retroperitoneum rarely involve the upper gastrointestinal tract. We describe an unusual case of contained small bowel perforation as a complication of chemotherapy treatment of metastatic non seminomatous germ ...
Ehab Helmy   +8 more
core  

CD30 and CD117 (c-kit) Used in Combination Are Useful for Distinguishing Embryonal Carcinoma from Seminoma

open access: yes, 2002
Germ-cell tumors are the most common malignant neoplasms of the testis. Seminomatous and non-seminomatous tumors must be differentiated because the treatment and the prognosis are different.
David Augusto   +3 more
core   +1 more source

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