Results 81 to 90 of about 46,014 (221)

The Role of (Line‐Field Confocal) Optical Coherence Tomography and Reflectance Confocal Microscopy in the Diagnosis of a Malignant Eccrine Differentiated Sweat Gland Tumour With Features of a Porocarcinoma and an Eccrine Spiradenocarcinoma: A Case Report

JEADV Clinical Practice
Malignant eccrine differentiated sweat gland tumours, including porocarcinoma and eccrine spiradenocarcinoma, are rare and aggressive neoplasms that pose diagnostic and therapeutic challenges.
Sandra Schuh, Marco Mozaffari, Kristina Fünfer, Wera Heinz, Oliver Jonas Mayer, Sophia Schlingmann, Martha Paola Mireles Canales, Deborah Winkler, Karisa Thölken, Uta Bachter, Julia Welzel   +10 more
doaj   +1 more source

Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53

Advanced Science, EarlyView.
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore, Andrea Basile, Stefano Freddi, Irene Schiano Lomoriello, Carlo Ribelle Zucca, Giuseppe Ciossani, Luigi Scietti, Alessandro Cuomo, Simona Ronzoni, Simone Pelicci, Mario Faretta, Elena Zaccheroni, Giuliana Pelicci, Vittoria Matafora, Angela Bachi, Rosalind Helen Gunby, Salvatore Pece, Sara Sigismund, Letizia Lanzetti, Ivan Nicola Colaluca, Pier Paolo Di Fiore   +20 more
wiley   +1 more source

Real‐Time In Vivo Cellular‐Level Imaging During Puncture

Advanced Science, EarlyView.
We present an artificial‐intelligence‐empowered integrative‐light‐field microendoscopy (AIM) needle that delivers real‐time in vivo, diffraction‐limited cellular‐level imaging during puncture and visualizes layered microstructures along the needle path. As a microscopic complement to CT/ultrasound, it improves sampling localization and adds preliminary
Huifang Gao, Jiakang Shao, Quanzhi Li, Yizhou Tan, Liangliang Huang, Xiaorong Xu, Ji Qi, Julin Xiao, Wenwen Li, Zhong Wen, Le Wang, Xu Liu, Qing Yang, Ying Gu   +13 more
wiley   +1 more source

Cohort‐Scale Spatial Autocorrelation for Tumor Prediction in Mid‐Infrared Pathology and Spatial Biomarker Discovery Using MALDI Imaging Lipidomics

Advanced Science, EarlyView.
Computational annotation of various tissue types in heterogeneous samples such as colorectal cancer liver metastasis (CRLM) using spatial autocorrelation analysis on non‐destructive mid‐infrared (MIR) imaging data enabled correlative multimodal mass spectrometry imaging (MSI) for spatial investigation of lipid tumor marker candidates. The method can be
Miriam F. Rittel, Nikolas Ebert, Denis Abu Sammour, Sebastian Graf, Björn C. Fröhlich, Emrullah Birgin, Shad A. Mohammed, Nuh N. Rahbari, Axel Wellmann, Oliver Wasenmüller, Cleo‐Aron Weis, Stefan Schmidt, Carsten Hopf   +12 more
wiley   +1 more source

Pigmented Bowen’s disease presenting clinically as longitudinal melanonychia

Revista da Sociedade Portuguesa de Dermatologia e Venereologia
Bowen’s disease (BD) is a squamous cell carcinoma, which affects more the elderly population and is more prevalent in light-skinned individuals. It affects most frequently sun-exposed areas and generally manifests as a single erythematous, scaly, or ...
Lucas S. Madureira, Vivian W. Lederman, Julia C. K. El Dib, Paula F. M. Madureira, Lucas K. Fernandes, Eduardo C.N. Constantino   +5 more
doaj  

Primary cutaneous signet ring cell carcinoma expressing cytokeratin 20 immunoreactivity [PDF]

, 2006
Primary cutaneous signet ring cell carcinoma (PCSRCC) is a very unusual but distinctive clinicopathologic entity that can simulate metastatic adenocarcinomas.
59244, 59245, 59246, 59247, 59248, ANSAI, Shinichi, KIYOHARA, Takahiro, KOURABA, Sachio, KUMAKIRI, Masanobu, TOKURIKI, Atsushi   +9 more
core   +1 more source

His‐MMDM: Multi‐Domain and Multi‐Omics Translation of Histopathological Images with Diffusion Models

Advanced Science, EarlyView.
His‐MMDM is a diffusion model‐based framework for scalable multi‐domain and multi‐omics translation of histopathological images, enabling tasks from virtual staining, cross‐tumor knowledge transfer, and omics‐guided image editing. ABSTRACT Generative AI (GenAI) has advanced computational pathology through various image translation models.
Zhongxiao Li, Tianqi Su, Bin Zhang, Wenkai Han, Sibin Zhang, Guiyin Sun, Yuwei Cong, Xin Chen, Jiping Qi, Yujie Wang, Shiguang Zhao, Hongxue Meng, Peng Liang, Xin Gao   +13 more
wiley   +1 more source

Análise da expressão do antígeno CD83 no fibroadenoma mamário humano e no tecido adjacente [PDF]

, 2011
CONTEXT AND OBJECTIVE: Dendritic cell maturation is considered essential for starting an immune response. The CD83 antigen is an important marker of dendritic cell maturation.
Borges, Marcus Nascimento, Facina, Gil, Nazário, Afonso Celso Pinto, Silva, Ismael Dale Cotrim Guerreiro da, Waitzberg, Angela Flávia Logullo   +4 more
core   +1 more source

Laparoscopic and Endoscopic Cooperative Surgery for Gastric Cancer as an Alternative Treatment in Elderly Patients: A Prospective Observational Study

Annals of Gastroenterological Surgery, EarlyView.
In a prospective study of 20 elderly gastric cancer patients who declined gastrectomy, laparoscopic and endoscopic cooperative surgery (LECS) was technically safe and preserved postoperative function. However, as oncological curability cannot be assured in advanced cases, careful selection and informed consent are essential.
Marie Washio, Keishi Yamashita, Takuya Wada, Mikiko Sakuraya, Hiroki Harada, Tadashi Higuchi, Koshi Kumagai, Yasushi Orihashi, Chika Kusano, Naoki Hiki   +9 more
wiley   +1 more source

Can Diffusion weighted MR imaging add diagnostic information in the evaluation of uterine tumor? [PDF]

, 2012
Purpose: to evaluate the role of DW imaging in the detection of cervical and endometrial cancers and correlate the histopathological grading and ADC values. Materials and Methods: 53 women with positive biopsy for cervical and endometrial cancer enrolled
FRUZZETTI, ELENA
core