Results 131 to 140 of about 533,074 (342)

miR-184 represses β-catenin and behaves as a skin tumor suppressor

Cell Death and Disease
miR-184-knockout mice display perturbed epidermal stem cell differentiation. However, the potential role of miR-184 in skin pathology is unclear. Here, we report that miR-184 controls epidermal stem cell dynamics and that miR-184 ablation enhances skin ...
Lubov Turovsky, Ghazal Kheshaiboun, Gharam Yassen, Sara Nagosa, Ilanit Boyango, Aya Amitai-Lange, Swarnabh Bhattacharya, Neta Ilan, Israel Vlodavsky, Daniel Aberdam, Ruby Shalom-Feuerstein, Emily Avitan-Hersh   +11 more
doaj   +1 more source

Model‐informed precision dosing of carboplatin in cancer patients by leveraging myelosuppression data from electronic health records

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims This study aimed to develop and validate a population pharmacokinetic‐pharmacodynamic (pop‐PK‐PD) model to describe carboplatin‐induced myelosuppression in cancer patients and support dose individualization. Methods Data from 580 cancer patients treated with carboplatin at Amsterdam UMC between 2019 and 2022 were used for model ...
Alessandro De Carlo, Elena Maria Tosca, Mirjam Crul, Tim Schutte, Lia van Zuijlen, Idris Bahce, Medhat M. Said, Jan Buter, Harmen Huls, Paolo Magni, Imke Bartelink   +10 more
wiley   +1 more source

Claudin-1 and Ki-67 expression in oral leukoplakia and oral squamous cell carcinoma

RUDN Journal of Medicine, 2010
The correlation was investigated between the level of cell proliferation and the intensity of claudin-1 expression in oral Leukoplakia with different grade of cell neoplastic transformation (according to WHO classification 2005, - SIN - Squamous ...
A A Katushkina, V A Koviazin, I I Babichenko, A S Grigorian   +3 more
doaj  

Althaea rosea Cavanil and Plantago major L. suppress neoplastic cell transformation through the inhibition of epidermal growth factor receptor kinase.

Molecular Medicine Reports, 2012
Eun‐Sun Choi, Sung-Dae Cho, Ji-Ae Shin, K. Kwon, N. Cho, J. Shim   +5 more
semanticscholar   +1 more source

Immortalization without neoplastic transformation of human mesenchymal stem cells by transduction with HPV16 E6/E7 genes [PDF]

, 2004
Shih‐Chieh Hung, Den‐Mei Yang, Ching‐Fang Chang, Ruey‐Jen Lin, Jih‐Shiuan Wang, Larry L.-T. Ho, Wen Yang   +6 more
openalex   +1 more source

Harnessing nanomaterials to precisely regulate the immunosuppressive tumor microenvironment for enhanced immunotherapy

BMEMat, EarlyView.
The immunosuppressive tumor microenvironment, characterized by hypoxia, redox imbalance, elevated interstitial fluid pressure, and acidity, was comprehensively elucidated. This review discussed the etiology and consequences of the characteristics of the immunosuppressive tumor microenvironment, and analyzed the recent advancements in nanomaterials for ...
Wen Zhang, Xueyin Hu, Wei Cheng, Lumeng Zhang, Yuanfang Chen, Qinrui Fu, Luntao Liu, Saijun Fan   +7 more
wiley   +1 more source

3D bioprinting in oral and craniomaxillofacial tissue regeneration: Progress, challenges, and future directions

BMEMat, EarlyView.
This paper summarized the application of 3D bioprinting in the regeneration of various tissues in the oral and craniomaxillofacial fields, including the required biomaterials and printing techniques. Abstract Oral and craniomaxillofacial tissues are essential for maintaining oral functions, including respiration, mastication, swallowing, and speech ...
Huilu Zhan, Haohao Ni, Xingge Yu, Mazaher Gholipourmalekabadi, Tianqi Wang, Kaili Lin, Jinsong Pan, Changyong Yuan   +7 more
wiley   +1 more source

Identification of tumor initiating cells and early marker genes in normal colonic epithelium that lead to neoplastic transformation [PDF]

Sangeeta Jaiswal, Stephanie The, Tse-Shao Chang, Jiaqi Shi, Thomas D. Wang   +4 more
openalex   +1 more source

Alteration of cell cycle kinase complexes in human papillomavirus E6- and E7-expressing fibroblasts precedes neoplastic transformation.

, 2020
Yue Xiong
openalex   +1 more source

Hemangioblastomas might derive from neoplastic transformation of neural stem cells/progenitors in the specific niche [PDF]

, 2010
Dexuan Ma, Mingchang Zhang, Liang Chen, Qisheng Tang, Xu Tang, Ying Mao, Liangfu Zhou   +6 more
openalex   +1 more source