Results 151 to 160 of about 7,162,308 (203)
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Neoplastic transformation of primary tracheal epithelial cell cultures
Carcinogenesis, 1983Primary cultures of rat tracheal epithelial cells were treated with the chemical carcinogen N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) to quantitatively study the early events during neoplastic transformation. Epithelial cells were dissociated from tracheas of specific-pathogen-free Fischer-344 rats and were plated on collagen-coated tissue culture ...
S B, Pai, V E, Steele, P, Nettesheim
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Neoplastic transformation of rabbit cells by murine sarcoma viruses
International Journal of Cancer, 1982AbstractNeoplastic transformation of rabbit cells by Kirsten murine sarcoma virus (Ki‐MSV), the Ki‐MSV pseudotype of baboon endogenous virus (Ki‐MSV[BaEV]) and the Moloney‐MSV pseudotype of feline leukemia virus (M‐MSV[FeLV]) is reported. Rabbit cells can be readily transformed by Ki‐MSV, Ki‐MSV(BaEV) and M‐MSV(FeLV). Rabbit cells transformed by Ki‐MSV
Rhim, J S, Bedigian, H G, Fox, R R
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Cell Surfaces in Neoplastic Transformation
1971Publisher Summary This chapter describes the properties, and the chemical and physiological aspects of cell surfaces in neoplastic transformation. Immunological surface disparities between normal and tumor cells have been studied for decades, while attempts to bring them into the realm of biochemistry have been extremely rare.
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Quantitative Neoplastic Transformation in C3H/10T1/2 Cells
1985The development of mammalian cell culture systems in which neoplastic transformation can be induced by exposure to chemical and physical carcinogens provided a major stimulus to the study of carcinogenic mechanisms. Furthermore, the potential ability to quantitate the induction of neoplasia on a per cell basis has allowed the study of factors ...
J S, Bertram, J E, Martner
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Transforming growth factors and control of neoplastic cell growth
Journal of Cellular Biochemistry, 1987AbstractTransforming growth factors (TGFs) are peptides that affect the growth and phenotypic of cultured cells and bring about in nonmalignant fibroblastic cells phenotypic properties that resemble those of malignant cells. Two types of TGFs have been well characterized.
J, Keski-Oja +4 more
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Neoplastic transformation of hamster embryo cells by heavy ions
Advances in Space Research, 1998We have studied the induction of morphological transformation of Syrian hamster embryo cells by low doses of heavy ions with different linear energy transfer (LET), ranging from 13 to 400 keV/micrometer. Exponentially growing cells were irradiated with 12C or 28Si ion beams generated by the Heavy Ion Medical Accelerator in Chiba (HIMAC), inoculated to ...
Z, Han +6 more
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Some Characteristics of Neoplastic Cell Transformation in Transgenic Mice
1996The role of the expression of different cellular genes and viral oncogenes in malignant cell transformation is discussed. We pay special attention to the role of the genes for growth factors and their receptors and homeobox genes in oncogenesis. Based on both the literature and our own data, specific features of tumors developed in transgenic mice are ...
I N, Shvemberger, A N, Ermilov
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The Pathway of Neoplastic Transformation of Human Breast Epithelial Cells
Radiation Research, 2001The morphological analysis of breast cancer development indicates this to be a multistep process that progressively evolves from ductal hyperplasia and atypical ductal hyperplasia, which represent the initial stages of neoplastic growth, to carcinoma in situ, invasive carcinoma, and ultimately metastasis, as has been documented for a number of other ...
J, Russo, I H, Russo
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Infrared parameters in the characterization of the neoplastic cell transformation
Microchemical Journal, 1992Abstract In this paper we report the results on the characterization of neoplastic cells by means of FT-IR spectroscopy. Spectral differences have been found in examining normal and leukemic lymphocytes. Through analyzing also nuclei extracted from normal and leukemic lymphocytes an increase of DNA with respect to proteic components was observed in ...
Enzo Benedetti +7 more
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Epigenetic Transformation by RNA from Human Neoplastic Cells
Oncology, 2009The study of biologic properties of nucleic acids from either normal or malignant cells transcends the search for subviral infectivity. The differing results obtained in studying the behavior of nucleic acids from human malignant cells on primary cultures are critically reviewed in the light of the methodology involved.
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