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In Which Cells Does Neoplastic Transformation Occur in Myelomatosis?
1992Myelomatosis is strictly a neoplasm of plasma cells in bone marrow. It does not involve other sites of antibody production; thus, even when the monoclonal protein produced by the neoplastic clone is IgA1 or IgA2 the neoplastic cells are not found in the lamina propria of the gut (Leonard et al 1979).
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[Differentiation and the neoplastic transformation of normal cells].
Tsitologiia, 1984It is suggested that blastomogenic factors can be considered as the means isolating normal cells from each other. Carcinogenic substances caused cell functions to disturb, to inhibit or to intensify the synthesis of specific substances, to change the cell surface disrupted contacts of interactions between cells, pressing cells to become on the way of ...
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Neoplastic transformation of human cells in vitro.
Critical reviews in oncogenesis, 1993Efforts to investigate the progression of events that lead normal human cells in culture to become neoplastic in response to carcinogenic agents have been aided by the development of the suitable in vitro model systems. For initial human cell transformation studies, a flat, nontumorigenic clonal line, originally derived from a human osteosarcoma (HOS),
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Positive Mediators of Cell Proliferation in Neoplastic Transformation
2002Cancer is not a single disease, but a collection of diseases all of which are related by a common root cause: the loss of controlled cell growth. Cancer begins as a clonal disease, that is, it stems from the genetic corruption of a single cell. This conversion of a normal cell into the neoplastic state is a multi-step phenomenon called neoplastic ...
James N. Welch, Susan A. Chrysogelos
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NEOPLASTIC TRANSFORMATION OF RAT LIVER EPITHELIAL CELLS IN CULTURE*
Annals of the New York Academy of Sciences, 1980R, Montesano +5 more
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THE CELL CYCLE AND THE NEOPLASTIC TRANSFORMATION
1974Jung-Chung Lin, Renato Baserga
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Diagnosis and Treatment of Neoplastic Effusions
Ca-A Cancer Journal for Clinicians, 1962John E Ultmann
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