Results 81 to 90 of about 7,162,308 (203)

Spontaneous neoplastic transformation frequency in the progeny of bystander C3H 10T½ MEFs.

, 2013
Co-culture of bystander C3H 10T½ MEFs with MEFs exposed to 0 or 25 cGy of 1 GeV/nucleon iron ions results in increased frequency of spontaneous neoplastic transformation in the distant progeny of the bystander cells. Neoplastic transformation frequencies
Manuela Buonanno (349029), Sonia M. de Toledo (349031), Edouard I. Azzam (349032)   +2 more
core   +1 more source

Constitutive activation of the CD40 pathway promotes cell transformation and neoplastic growth

, 2005
CD40, a tumour necrosis factor (TNF) receptor family member, is expressed in a variety of cell types, including B lymphocytes, macrophages, fibroblasts, endothelial and epithelial cells, and this widespread expression is likely to account for its central
Stewart, Suzanne, Young, Lawrence, Baxendale, Amanda, Gordon, John, Murray, Paul, Eliopoulos, Aristides, Mudaliar, V, Dawson, Christopher, Reynolds, Gary; id_orcid   +8 more
core   +1 more source

miR-184 represses β-catenin and behaves as a skin tumor suppressor

Cell Death and Disease
miR-184-knockout mice display perturbed epidermal stem cell differentiation. However, the potential role of miR-184 in skin pathology is unclear. Here, we report that miR-184 controls epidermal stem cell dynamics and that miR-184 ablation enhances skin ...
Lubov Turovsky, Ghazal Kheshaiboun, Gharam Yassen, Sara Nagosa, Ilanit Boyango, Aya Amitai-Lange, Swarnabh Bhattacharya, Neta Ilan, Israel Vlodavsky, Daniel Aberdam, Ruby Shalom-Feuerstein, Emily Avitan-Hersh   +11 more
doaj   +1 more source

Diffusion and binding data.

, 2017
(A) Line plot of EGFP diffusion vs. cancer cell type (neoplastic transformation). (B) Line plot of the pseudo-equilibrium constant K* for MutSα-EGFP as a function of cancer cell type (neoplastic transformation) for both cell regions.
Karin Scarpinato (3710359), Josiah Low (3710356), Tracey Pu (3710353), Daniel Nelli (3710344), Justin Sigley (3710347), Martin Guthold (270306), Keith Bonin (227243), John Jarzen (3710350)   +7 more
core   +1 more source

The Autoimmune Gastritis Puzzle: Emerging Cellular Crosstalk and Molecular Pathways Driving Parietal Cell Loss and ECL Cell Hyperplasia

Cells
Autoimmune gastritis (AIG) is a chronic, organ-specific autoimmune disease characterized by progressive destruction of gastric parietal cells driven by autoreactive CD4+ T-cells, epithelial stress pathways, and microbial factors.
Sara Massironi, Elena Oriani, Giuseppe Dell’Anna, Silvio Danese, Federica Facciotti   +4 more
doaj   +1 more source

Oncogenic Kit controls neoplastic mast cell growth through a Stat5/PI3-kinase signaling cascade

, 2008
International audienceThe D816V-mutated variant of Kit triggers multiple signaling pathways and is considered essential for malignant transformation in mast cell (MC) neoplasms.
Kerenyi, Marc, Gouilleux, Fabrice, Katrin Friedbichler, Isabelle Dusanter-Fourt, Gondry, Jean, Valérie Gouilleux-Gruart, Martin-Lannerée, Séverine, Séverine Martin-Lannerée, Boudot, Cedric, Valent, Peter, Laurence Bénit, Gouilleux-Gruart, Valérie, Bénit, Laurence, Noria Harir, Marc Kerenyi, Rudin Kondo, Jean Gondry, Richard Moriggl, Peter Valent, Lukas Kenner, Lassoued, Kaiss, Harir, Noria, Moriggl, Richard, Saliha Yahiaoui, Friedbichler, Katrin, Karoline Sonneck, Yahiaoui, Saliha, Kondo, Rudin, Sonneck, Karoline, Dusanter-Fourt, Isabelle, Cédric Boudot, Fabrice Gouilleux, Kenner, Lukas, Kaïss Lassoued   +33 more
core   +1 more source

Claudin-1 and Ki-67 expression in oral leukoplakia and oral squamous cell carcinoma

RUDN Journal of Medicine, 2010
The correlation was investigated between the level of cell proliferation and the intensity of claudin-1 expression in oral Leukoplakia with different grade of cell neoplastic transformation (according to WHO classification 2005, - SIN - Squamous ...
A A Katushkina, V A Koviazin, I I Babichenko, A S Grigorian   +3 more
doaj  

E.: Neoplastic transformation of mouse and hamster cells in vitro with and without polyoma virus

, 1967
SUMMARY-Several cell lines were examined under different culture conditions in an effort to find one that would not undergo "spontaneous" neoplastic transformation but could be transformed by polyoma virus.
Katherine K. Sanford, Robert E. Hoemann, Sanford, K K, Hoemann, R E   +3 more
core  

Neoplastic transformation by truncated alleles of human NOTCH1/TAN1 and NOTCH2

, 1997
The Notch genes of Drosophila melanogaster and vertebrates encode transmembrane receptors that help determine cell fate during development. Although ligands for Notch proteins have been identified, the signaling cascade downstream of the receptors ...
Bishop, J M, Artavanis-Tsakonas, S, Capobianco, A J, Blaumueller, C M, Zagouras, P   +4 more
core   +1 more source

Unveiling cell-type-specific microRNA networks through alternative polyadenylation in glioblastoma

BMC Biology
Background Glioblastoma multiforme (GBM) is characterized by its cellular complexity, with a microenvironment consisting of diverse cell types, including oligodendrocyte precursor cells (OPCs) and neoplastic CD133 + radial glia-like cells.
Mert Cihan, Greta Schmauck, Maximilian Sprang, Miguel A. Andrade-Navarro   +3 more
doaj   +1 more source