Results 151 to 160 of about 330,598 (225)

Blood tumor load: combining biomarkers to increase the proportion of informative patients. [PDF]

open access: yesESMO Open
Dathathri E   +7 more
europepmc   +1 more source

Oxytocin Enhances Demethylation Through TET Enzyme Expression in Neurons of Aged Mice: Oxytocin as a Potential Antiaging Peptide

open access: yesAging Cell, EarlyView.
DNA methylation, mitochondrial dysfunction, inflammation, and senescence interact to form a vicious cycle. Here we report that oxytocin interrupts this vicious cycle by increasing TET2 expression, inducing DNA demethylation in aged neurons and raising plasma oxytocin levels, decreasing systemic inflammation.
Yuko Maejima   +8 more
wiley   +1 more source

Prognosis of Invasive Lobular Carcinoma and Effectiveness of Eribulin in Clinical Practice: A Post Hoc Analysis of a 2‐Year Post‐Marketing Surveillance

open access: yesAsia-Pacific Journal of Clinical Oncology, EarlyView.
This post hoc analysis of a post‐marketing surveillance evaluated the prognosis of patients with invasive lobular carcinoma (ILC) or invasive ductal carcinoma (IDC) treated with eribulin. Overall survival (OS) from the first‐line chemotherapy was shorter for ILC than IDC cases, but OS from the first date of eribulin administration were similar between ...
Yuko Tanabe   +10 more
wiley   +1 more source

Personalized Cancer Vaccines in the Clinical Trial Pipeline

open access: yesAsia-Pacific Journal of Clinical Oncology, EarlyView.
This study analyzes the current landscape of personalized cancer vaccine clinical trials, highlighting trends in vaccine platforms, trial phases, and geographic distribution. Peptide and dendritic cell vaccines dominate early‐stage research, with promising immune responses observed in melanoma, glioblastoma, and urothelial cancer trials.
Liudmila Iamukova, Elena Alferova
wiley   +1 more source

IgG4‐Related Disease: Emerging Roles of Novel Genetic Variants, Immune Cell Subsets and Therapeutic Targets

open access: yesAllergy, EarlyView.
ABSTRACT IgG4, the least abundant IgG subclass in humans, is increasingly recognised for its involvement in allergic and autoimmune pathologies. Its unique properties, such as the tendency to form half‐molecules (one heavy chain and one light chain) and its generally non‐inflammatory nature, distinguish it from other IgG subclasses.
Louisa Tedesco   +8 more
wiley   +1 more source

Tumor Microenvironment in Melanoma Brain Metastasis: A New Potential Target? [PDF]

open access: yesInt J Mol Sci
Caruso G   +7 more
europepmc   +1 more source

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