Results 11 to 20 of about 217,168 (254)
Heterogeneity of Circulating Tumor Cell Neoplastic Subpopulations Outlined by Single-Cell Transcriptomics [PDF]
Fatal metastasis occurs when circulating tumor cells (CTCs) disperse through the blood to initiate a new tumor at specific sites distant from the primary tumor. CTCs have been classically defined as nucleated cells positive for epithelial cell adhesion molecule and select cytokeratins (EpCAM/CK/DAPI), while negative for the common lymphocyte marker ...
Christine M. Pauken +5 more
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Current Status and Prospects of Liquid Biopsy for Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths globally. Early detection and treatment response monitoring of HCC are vital for improved outcomes.
Jumi Kang, Soon Sun Kim
doaj +1 more source
In vitro assessment of antiproliferative action selectivity of dietary isothiocyanates for tumor versus normal human cells [PDF]
Background/Aim. Numerous epidemiological studies have shown beneficial effects of cruciferous vegetables consumption in cancer chemoprevention.
Konić-Ristić Aleksandra +6 more
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Circulating Cell-Free DNA in Dogs with Mammary Tumors: Short and Long Fragments and Integrity Index. [PDF]
Circulating cell-free DNA (cfDNA) has been considered an interesting diagnostic/prognostic plasma biomarker in tumor-bearing subjects. In cancer patients, cfDNA can hypothetically derive from tumor necrosis/apoptosis, lysed circulating cells, and some ...
Giorgia Beffagna +14 more
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Cancer remains a significant cause of mortality in developed countries, due in part to difficulties in early detection, understanding disease biology, and assessing treatment response. If effectively harnessed, circulating biomarkers promise to fulfill these needs through non-invasive “liquid” biopsy.
Thomas L. Sutton +6 more
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Epithelial cell adhesion molecule (EpCAM) is a transmembrane protein expressed at intercellular junctions in epithelial cells. As an epithelial biomarker, it used for immunologic-based capture of epithelial-derived circulating tumor cells (CTCs) in human
Christa Y. Heyward +4 more
doaj +1 more source
Relevance of circulating hybrid cells as a non-invasive biomarker for myriad solid tumors
Metastatic progression defines the final stages of tumor evolution and underlies the majority of cancer-related deaths. The heterogeneity in disseminated tumor cell populations capable of seeding and growing in distant organ sites contributes to the ...
Matthew S. Dietz +33 more
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Background We tested the hypothesis that radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC) promotes tumor cell release and explored a method for reducing these effects.
Bowen Zhuang +8 more
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An updated portrait of monocyte-macrophages in classical Hodgkin lymphoma
Classical Hodgkin lymphoma (cHL) is a unique neoplastic ecosystem characterized by a heterogeneous immune infiltrate surrounding the rare malignant Hodgkin Reed-Sternberg cells.
Isacco Ferrarini +5 more
doaj +1 more source
Nuclear morphometry and ploidy of normal and neoplastic haemocytes in mussels. [PDF]
Haemic neoplasia (HN) in bivalves has been reported in association with mass mortality events in various species of molluscs. The aim of this work was to quantify the nuclear morphometry and DNA content of neoplastic cells of mussels Mytilus ...
Francesca Carella +2 more
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