Results 11 to 20 of about 508,130 (309)

Circulating Neoplastic-Immune Hybrid Cells Predict Metastatic Progression in Uveal Melanoma

Cancers, 2022
Background: Uveal melanoma is an aggressive cancer with high metastatic risk. Recently, we identified a circulating cancer cell population that co-expresses neoplastic and leukocyte antigens, termed circulating hybrid cells (CHCs). In other cancers, CHCs
Michael S Parappilly, Yuki Chin, Riley M Whalen   +2 more
exaly   +5 more sources

Neoplastic circulating endothelial cells in multiple myeloma with 13q14 deletion

Blood, 2006
In multiple myeloma (MM), circulating endothelial cells (CECs) represent a vascular marker of angiogenesis and may reflect tumor mass. In this report, we showed that, in 5 MM patients with 13q14 deletion, CECs carried the same chromosome aberration as ...
Gian Matteo Rigolin, Massimo Negrini, Gianluigi Castoldi   +2 more
exaly   +7 more sources

Circulating Cells with Macrophage-like Characteristics in Cancer: The Importance of Circulating Neoplastic-Immune Hybrid Cells in Cancer

Cancers, 2022
SIMPLE SUMMARY: In cancer, disseminated neoplastic cells circulating in blood are a source of tumor DNA, RNA, and protein, which can be harnessed to diagnose, monitor, and better understand the biology of the tumor from which they are derived ...
Wong, Melissa H., Thomas L. Sutton, Anderson, Ashley N., Whalen, Riley, Melissa H. Wong, Ranish K. Patel, Giske, Nicole R., Sutton, Thomas L., Patel, Ranish K., Stephen G. Bowden, Bowden, Stephen G., Ashley N. Anderson, Nicole R. Giske, Riley Whalen   +13 more
core   +4 more sources

Label-free enrichment of rare unconventional circulating neoplastic cells using a microfluidic dielectrophoretic sorting device [PDF]

Communications Biology, 2021
Montoya Mira & Sapre et al. design a microfluidic device utilizing dielectrophoresis for the enrichment of circulating neoplastic cells that possess both epithelial and immune-like characteristics. They optimized the device using in vitro models and then
Jose Montoya Mira, Ajay A. Sapre, Brett S. Walker, Jesus Bueno Alvarez, Kyle T. Gustafson, Eugene Tu, Jared M. Fischer, Melissa H. Wong, Sadik Esener, Yu-Jui Chiu   +9 more
doaj   +5 more sources

Flow cytometry in the detection of circulating tumor cells in neoplastic effusions

Clinica Chimica Acta, 2023
Despite its limitations, the cytology of body fluids is widely used in diagnosing neoplastic cells. Flow cytometry detects and identifies individual cells, enabling the detection of circulating tumor cells and facilitating diagnosis. This study compared the diagnostic utility of flow cytometry and cytology for detecting cancer cells in peritoneal and ...
Karol Gostomczyk, Marek Zdrenka, Łukasz Szylberg   +2 more
exaly   +4 more sources

Extragenital transmissible venereal tumour associated with circulating neoplastic cells in an immunologically compromised dog

Veterinary and Comparative Oncology, 2006
An adult male intact boxer was presented because of diffuse cutaneous nodules. Fine-needle aspirate revealed transmissible venereal tumour (TVT) cells. Neoplastic cells were also observed in the peripheral blood. Associated simultaneous diseases included
Albanese, F, Giordano, S, Marconato, L, Salerni, F L   +3 more
core   +5 more sources

Circulating angiogenic cells in glioblastoma: toward defining crucial functional differences in CAC-induced neoplastic versus reactive neovascularization [PDF]

Neuro-Oncology Advances, 2020
Background: In order to identify suitable therapeutic targets for glioma anti-angiogenic therapy, the process of neovascularization mediated by circulating angiogenic cells (CACs) needs to be scrutinized.
Andrea Sacchetti, Sigrid Swagemakers, Peter J Van Der Spek   +2 more
exaly   +7 more sources

Detection of circulating neoplastic cells by reverse-transcriptase polymerase chain reaction in malignant melanoma: association with clinical stage and prognosis.

Journal of Clinical Oncology, 1996
PURPOSE Circulating melanoma cells can be detected in peripheral blood by means of tyrosinase mRNA amplification by reverse-transcriptase polymerase chain reaction (RT-PCR).
B Mellado, M Muñoz, J J Grau, J L Vives-Corrons, E Carballo, J M Mascaró, T Castel, D Colomer, M Galán, J Estapé   +9 more
core   +4 more sources

Exploratory Analyses of Circulating Neoplastic-Immune Hybrid Cells as Prognostic Biomarkers in Advanced Intrahepatic Cholangiocarcinoma

International Journal of Molecular Sciences
Existing clinical biomarkers do not reliably predict treatment response or disease progression in patients with advanced intrahepatic cholangiocarcinoma (ICC).
Ranish K Patel, Michael S Parappilly, Brett S Walker   +2 more
exaly   +4 more sources

Heterogeneity of Circulating Tumor Cell Neoplastic Subpopulations Outlined by Single-Cell Transcriptomics [PDF]

Cancers, 2021
Fatal metastasis occurs when circulating tumor cells (CTCs) disperse through the blood to initiate a new tumor at specific sites distant from the primary tumor. CTCs have been classically defined as nucleated cells positive for epithelial cell adhesion molecule and select cytokeratins (EpCAM/CK/DAPI), while negative for the common lymphocyte marker ...
Christine M. Pauken, Shelby Ray Kenney, Kathryn J. Brayer, Yan Guo, Ursa A. Brown-Glaberman, Dario Marchetti   +5 more
semanticscholar   +4 more sources