Results 11 to 20 of about 247,318 (300)

Circulating Neoplastic-Immune Hybrid Cells Predict Metastatic Progression in Uveal Melanoma

Cancers, 2022
Background: Uveal melanoma is an aggressive cancer with high metastatic risk. Recently, we identified a circulating cancer cell population that co-expresses neoplastic and leukocyte antigens, termed circulating hybrid cells (CHCs). In other cancers, CHCs are more numerous and better predict oncologic outcomes compared to circulating tumor cells (CTCs).
Michael S. Parappilly, Yuki Chin, Riley M. Whalen, Ashley N. Anderson, Trinity S. Robinson, Luke Strgar, Thomas L. Sutton, Patrick Conley, Christopher Klocke, Summer L. Gibbs, Young Hwan Chang, Guanming Wu, Melissa H. Wong, Alison H. Skalet   +13 more
openaire   +4 more sources

Neoplastic circulating endothelial cells in multiple myeloma with 13q14 deletion

Blood, 2006
Abstract In multiple myeloma (MM), circulating endothelial cells (CECs) represent a vascular marker of angiogenesis and may reflect tumor mass. In this report, we showed that, in 5 MM patients with 13q14 deletion, CECs carried the same chromosome aberration as the neoplastic plasma cells (11%-32% of CECs with 13q14 deletion). Most of the
RIGOLIN, Gian Matteo, FRAULINI, Chiara, CICCONE, Maria, MAURO, Endri, BUGLI, Anna Maria, DE ANGELI, Cristiano, NEGRINI, Massimo, CUNEO, Antonio, CASTOLDI, Gianluigi   +8 more
openaire   +6 more sources

Flow cytometry in the detection of circulating tumor cells in neoplastic effusions

Clinica Chimica Acta
Despite its limitations, the cytology of body fluids is widely used in diagnosing neoplastic cells. Flow cytometry detects and identifies individual cells, enabling the detection of circulating tumor cells and facilitating diagnosis. This study compared the diagnostic utility of flow cytometry and cytology for detecting cancer cells in peritoneal and ...
Karol Gostomczyk, Ewelina Łukaszewska, Jędrzej Borowczak, Anita Bator, Marek Zdrenka, Magdalena Bodnar, Łukasz Szylberg   +6 more
openaire   +4 more sources

Exploratory Analyses of Circulating Neoplastic-Immune Hybrid Cells as Prognostic Biomarkers in Advanced Intrahepatic Cholangiocarcinoma

International Journal of Molecular Sciences
Existing clinical biomarkers do not reliably predict treatment response or disease progression in patients with advanced intrahepatic cholangiocarcinoma (ICC). Circulating neoplastic-immune hybrid cells (CHCs) have great promise as a blood-based biomarker for patients with advanced ICC.
Ranish K. Patel, Michael S. Parappilly, Brett S. Walker, Robert T. Heussner, Alice Fung, Young Hwan Chang, Adel Kardosh, Charles D. Lopez, Skye C. Mayo, Melissa H. Wong   +9 more
openaire   +4 more sources

Radiofrequency ablation induces tumor cell dissemination in a mouse model of hepatocellular carcinoma

European Radiology Experimental, 2023
Background We tested the hypothesis that radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC) promotes tumor cell release and explored a method for reducing these effects.
Bowen Zhuang, Xi Zhu, Jinhua Lin, Fuli Zhang, Bin Qiao, Jihui Kang, Xiaohua Xie, Xunbin Wei, Xiaoyan Xie   +8 more
doaj   +1 more source

An updated portrait of monocyte-macrophages in classical Hodgkin lymphoma

Frontiers in Oncology, 2023
Classical Hodgkin lymphoma (cHL) is a unique neoplastic ecosystem characterized by a heterogeneous immune infiltrate surrounding the rare malignant Hodgkin Reed-Sternberg cells.
Isacco Ferrarini, Andrea Bernardelli, Ester Lovato, Alberto Schena, Mauro Krampera, Carlo Visco   +5 more
doaj   +1 more source

Nuclear morphometry and ploidy of normal and neoplastic haemocytes in mussels. [PDF]

PLoS ONE, 2017
Haemic neoplasia (HN) in bivalves has been reported in association with mass mortality events in various species of molluscs. The aim of this work was to quantify the nuclear morphometry and DNA content of neoplastic cells of mussels Mytilus ...
Francesca Carella, Gionata De Vico, Gabriel Landini   +2 more
doaj   +1 more source

Circulating angiogenic cells in glioblastoma: toward defining crucial functional differences in CAC-induced neoplastic versus reactive neovascularization [PDF]

Neuro-Oncology Advances, 2020
AbstractBackgroundIn order to identify suitable therapeutic targets for glioma anti-angiogenic therapy, the process of neovascularization mediated by circulating angiogenic cells (CACs) needs to be scrutinized.MethodsIn the present study, we compared the expression of neovascularization-related genes by 3 circulating CAC subsets (hematopoietic ...
Huizer, Karin, Sacchetti, Andrea, Swagemakers, Sigrid, Van Der Spek, Peter J., Dik, Wim, Mustafa, Dana A., Kros, Johan M.   +6 more
openaire   +4 more sources

Circulating Cells with Macrophage-like Characteristics in Cancer: The Importance of Circulating Neoplastic-Immune Hybrid Cells in Cancer

Cancers, 2022
Cancer remains a significant cause of mortality in developed countries, due in part to difficulties in early detection, understanding disease biology, and assessing treatment response. If effectively harnessed, circulating biomarkers promise to fulfill these needs through non-invasive “liquid” biopsy.
Thomas L. Sutton, Ranish K. Patel, Ashley N. Anderson, Stephen G. Bowden, Riley Whalen, Nicole R. Giske, Melissa H. Wong   +6 more
openaire   +2 more sources

Clinical Significance of Circulating Tumor Cells in Gastric Cancer

The Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2018
Cancer specimens obtained via surgical resection or biopsy are generally used to understand tumor-associated alterations; however, those approaches cannot always be performed because of their invasive nature, and they may fail to reflect current tumor ...
Hye Kyung Jeon, Gwang Ha Kim
doaj   +1 more source