Results 201 to 210 of about 432,951 (336)

Thermo‐Chemically Modified Silk Scaffolds Reveal Niche‐Driven Regulation of Hematopoiesis and Fibrosis

Small, EarlyView.
We introduce a versatile 3D platform that recreates key physical and biological features of the human bone marrow. By integrating tunable silk biomaterials, stromal cells, and human hematopoietic progenitors, the model captures both healthy and diseased microenvironments, analysis of blood formation, and its disruption in pathological conditions ...
Christian A. Di Buduo, Carolina P. Miguel, Giulia Della Rosa, Vittorio Abbonante, Santo Diprima, Delfina Tosi, Marta Filibian, Daniele Cattaneo, Jugal Kishore Sahoo, Nicola Tirelli, Alessandra Iurlo, Umberto Gianelli, David L. Kaplan, Alessandra Balduini   +13 more
wiley   +1 more source

I. Enhanced Autologous Immune Enhancement Therapy (AIET) for Cancer Treatment in Vietnam: From Clinical Trials to Broader. [PDF]

J Stem Cells Regen Med
Liem NT.
europepmc   +1 more source

Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state

, 2011
Christine L. Chaffer, Ines Brueckmann, Christina Scheel, Alicia J. Kaestli, Paul A. Wiggins, Leonardo O. Rodrigues, Mary W. Brooks, Ferenc Reinhardt, Ying Su, Kornélia Polyák, Lisa M. Arendt, Charlotte Kuperwasser, Brian Bierie, Robert A. Weinberg   +13 more
openalex   +2 more sources

Deciphering diverse cell‐death patterns to predict the prognosis and potential therapy target of hepatocellular carcinoma patients

VIEW, EarlyView.
Abstract Ninety percent of all primary liver malignancies are hepatocellular carcinomas (HCC), making liver cancer the third most common cause of cancer‐associated mortality. Different patterns of programmed cell death (PCD) are crucial for the survival of tumors, and they might serve as a prognostic marker for HCC.
Lin Ding, Qian Li, Wenjing Yang, Te Liu, Tongtong Tian, Yu Liu, Chunyan Zhang, Baishen Pan, Beili Wang, Fan Wu, Wei Guo   +10 more
wiley   +1 more source

Exploration of the Prognostic Role of Apoptosis-Related Genes in Glioblastoma. [PDF]

Stem Cells Int
Wang H, Yang L, Lu Y, Nair S.
europepmc   +1 more source

Single‐cell RNA sequencing revealed the T‐cell heterogeneity and exhaustion subsets of Helicobacter pylori‐induced gastritis‐to‐cancer transformation

VIEW, EarlyView.
H. pylori infection is a major cause of stomach cancer, but its effect on immune cells in tumors is unclear. Using single‐cell sequencing, we mapped the stomach tumor environment and discovered a specific exhausted T‐cell subtype, marked by the FYB1 gene, that is abundant in H. pylori‐positive tumors and linked to patient prognosis. Our findings reveal
Yanhui Yang, Yanxia Liu, Xiaole Guo, Zhaorun Li, Ziyu Liu, Shuming Zhang, Yuma Yang, Jun Liu, Shoucheng Ma, Linke Ma, Xianmei Chen, Xue Li, Yuanyuan Tang, Xiaoling Ding, Xiaofei Li, Qian Hao, Yanjie You, Tingting Yang, Qingrui Li, Xue Zhang, Sihan Zhang, Hengjun Gao, Shengjuan Hu   +22 more
wiley   +1 more source

Machine learning-based identification of kbhb-affected tumor cell subsets as prognostic and therapeutic targets in breast cancer. [PDF]

J Transl Med
Yuan Q, Sha Y, Ye R, Yu H, Ni L, Han J, Deng L.   +6 more
europepmc   +1 more source

Vascular Supply of Laryngeal Paragangliomas: Case Report and Systematic Review

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Laryngeal paragangliomas are rare, highly vascularized, neuroendocrine tumors. Although surgical resection of these vascular neoplasms is associated with a known risk of significant hemorrhage, the vascular supply of laryngeal paragangliomas has been poorly characterized. Data Sources MEDLINE Ovid, Embase, Scopus, and Google Scholar.
Jane Y. Tong, Talia Guardia, Emilie Ludeman, Kyle Hatten   +3 more
wiley   +1 more source

Tissue-Resident Myeloid and Histiocytic Cells in Health and Disease: Novel Emerging Concepts. [PDF]

Am J Hematol
Valent P, Wojta J, Kovanen PT, Hermine O, Fend F, Sotlar K, Greinix H, Geissler K, Hartmann K, Schwaab J, Herling M, Boccuni L, Kazianka L, John MV, Sperr WR, Zierfuss C, Tzankov A, Sillaber C, Minkov M, Hoermann G, Collin M, Horny HP, Haferlach T, Sibilia M, Haroche J, La Rosée P, Orfao A, Arock M.   +27 more
europepmc   +1 more source

Chinese Guidelines for Diagnosis and Treatment of Chronic Rhinosinusitis (2024)

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Chronic rhinosinusitis (CRS), a complex inflammatory disease with heterogeneous pathogenesis, demands evolving evidence‐based strategies. Since the 2018 Chinese guidelines and EPOS2020, international advances in CRS immunopathology and biologics have revolutionized therapeutic approaches, particularly through phenotype–endotype classification ...
Subspecialty Group of Rhinology, Editorial Board of Chinese Journal of Otorhinolaryngology Head and Neck Surgery, Subspecialty Group of Rhinology, Society of Otorhinolaryngology Head and Neck Surgery, Chinese Medical Association   +4 more
wiley   +1 more source